Results 31 to 40 of about 3,974,865 (310)

In silico evaluation of the interaction between ACE2 and SARS-CoV-2 Spike protein in a hyperglycemic environment

open access: yesScientific Reports, 2021
The worse outcome of COVID-19 in people with diabetes mellitus could be related to the non-enzymatic glycation of human ACE2, leading to a more susceptible interaction with virus Spike protein.
Giovanni Sartore   +5 more
doaj   +1 more source

Elucidating Interactions Between SARS-CoV-2 Trimeric Spike Protein and ACE2 Using Homology Modeling and Molecular Dynamics Simulations

open access: yesFrontiers in Chemistry, 2021
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). As of October 21, 2020, more than 41.4 million confirmed cases and 1.1 million deaths have been reported.
Sugunadevi Sakkiah   +8 more
doaj   +1 more source

Sea Urchin Pigments as Potential Therapeutic Agents Against the Spike Protein of SARS-CoV-2 Based on in Silico Analysis [PDF]

open access: yes, 2020
Several studies have been published regarding the interaction between the spike protein of the novel coronavirus SARS-CoV-2 and ACE2 receptor in the host cells.
Jimena Pía, Fernandez   +9 more
core   +5 more sources

Mutations and Evolution of the SARS-CoV-2 Spike Protein

open access: yesViruses, 2022
The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the viral infection that leads to various levels of COVID-19 severities. Positive evolutionary selection of mutations within the spike protein has led to the genesis
Nicholas Magazine   +5 more
doaj   +1 more source

Production and secretion of functional SARS-CoV-2 spike protein in Chlamydomonas reinhardtii

open access: yesFrontiers in Plant Science, 2022
The spike protein is the major protein on the surface of coronaviruses. It is therefore the prominent target of neutralizing antibodies and consequently the antigen of all currently admitted vaccines against SARS-CoV-2.
Anna Maria Kiefer   +4 more
doaj   +1 more source

HUMAN SARS CoV-2 SPIKE PROTEIN MUTATIONS [PDF]

open access: yes, 2020
The human SARS-CoV-2 spike protein sequences from Asia, Africa, Europe, North America, South America and Oceania were analyzed by comparing with the reference SARS-CoV-2 protein sequence from Wuhan-Hu-1, China.
Lalitha, Guruprasad
core   +1 more source

The avian coronavirus spike protein

open access: yesVirus Research, 2014
Avian coronaviruses of the genus Gammacoronavirus are represented by infectious bronchitis virus (IBV), the coronavirus of chicken. IBV causes a highly contagious disease affecting the respiratory tract and, depending on the strain, other tissues including the reproductive and urogenital tract.
I.N. Ambepitiya Wickramasinghe   +3 more
openaire   +5 more sources

A Fusion Peptide in the Spike Protein of MERS Coronavirus [PDF]

open access: yesViruses, 2019
Coronaviruses represent current and emerging threats for many species, including humans. Middle East respiratory syndrome-related coronavirus (MERS-CoV) is responsible for sporadic infections in mostly Middle Eastern countries, with occasional transfer elsewhere.
Entedar A. J. Alsaadi   +2 more
openaire   +4 more sources

Targeting the Interaction Between Spike Protein and Nucleocapsid Protein for Suppression and Detection of Human Coronavirus OC43

open access: yesFrontiers in Immunology, 2022
Human coronavirus OC43 (HCoV-OC43) is the coronavirus most associated with “common colds”, infections of the upper respiratory tract. Previously, we reported that direct interactions of nucleocapsid (N) protein and C-terminal domain of Spike protein ...
Jinsoo Kim   +11 more
doaj   +1 more source

Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis [PDF]

open access: yes, 2014
Recent evidence suggests that a mutation in the spike protein gene of feline coronavirus (FCoV), which results in an amino acid change from methionine to leucine at position 1058, may be associated with feline infectious peritonitis (FIP).
Tasker, S   +21 more
core   +1 more source

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