Results 31 to 40 of about 55,024 (303)
Kinect-based objective evaluation of bradykinesia in patients with Parkinson's disease
Digital Health, 2023 Objective To quantify bradykinesia in Parkinson's disease (PD) with a Kinect depth camera-based motion analysis system and to compare PD and healthy control (HC) subjects. Methods Fifty PD patients and twenty-five HCs were recruited.
Zhuang Wu +15 more
doaj +1 more source
Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]
, 2003 The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Todd, A.J. +7 more
core +1 more source
Frontiers in Cellular Neuroscience, 2022 Spinal cord injury (SCI) is caused by an external force, leading to severe dysfunction of the limbs below the injured segment. The inflammatory response plays a vital role in the prognosis of SCI.
Xu Zhu +9 more
doaj +1 more source
Regeneration in the spinal cord
Current Opinion in Neurobiology, 1998 Important advances have been made in our understanding of conditions that influence the intrinsic capacity of mature CNS neurons to initiate and maintain a regrowth response. The combination of exogenous neurotrophic support with strategies to alter the terrain at the injury site itself suggests that there are important interactions between them that ...
openaire +2 more sources
Why Would the Brain Need Dormant Neuronal Precursors?
Frontiers in Neuroscience, 2022 Dormant non-proliferative neuronal precursors (dormant precursors) are a unique type of undifferentiated neuron, found in the adult brain of several mammalian species, including humans.
Bruno Benedetti +5 more
doaj +1 more source
Science, 1996 A paper in this week's issue of Science (Cheng and Olson, p. 510 ) reports the first hint that truly functional regeneration of the adult spinal cord may be possible, at least in the rat. In his Perspective, Young describes why this demonstration of regeneration is so important but cautions ...
openaire +4 more sources
CXCR1 drives the pathogenesis of EAE and ARDS via boosting dendritic cells-dependent inflammation
Cell Death and Disease, 2023 Chemokines secreted by dendritic cells (DCs) play a key role in the regulation of inflammation and autoimmunity through chemokine receptors. However, the role of chemokine receptor CXCR1 in inflammation-inducing experimental autoimmune encephalomyelitis (
Wei Zhuang +14 more
doaj +1 more source
Developmental Biology, 2017 Repairing injured tissues / organs is one of the major challenges for the maintenance of proper organ function in adulthood. In mammals, the central nervous system including the spinal cord, once established during embryonic development, has very limited capacity to regenerate.
Akira, Tazaki +2 more
openaire +2 more sources
Cell therapy for spinal cord regeneration [PDF]
Advanced Drug Delivery Reviews, 2008 This review presents a summary of the various types of cellular therapy used to treat spinal cord injury. The inhibitory environment and loss of axonal connections after spinal cord injury pose many obstacles to regenerating the lost tissue. Cellular therapy provides a means of restoring the cells lost to the injury and could potentially promote ...
Stephanie M, Willerth +1 more
openaire +2 more sources
Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations
Neural Plasticity, 2014 Speculations on the involvement of hippocampal neurogenesis, a form of neuronal plasticity, in the aetiology of depression and the mode of action of antidepressive therapies, started to arise more than a decade ago.
Peter Rotheneichner +7 more
doaj +1 more source