Results 11 to 20 of about 55,024 (303)

Spinal cord conduits for spinal cord injury regeneration

open access: yesEngineered Regeneration, 2023
Spinal cord injury (SCI), which causes irreversible damage in both sensory and motor function, is considered an insurmountable challenge in the field of medicine. The previous researchers have developed many kinds of biomaterials for SCI, and spinal cord conduits (SCCs) are an important classification for bridging spinal cord tissues while performing ...
Yanyu Ma   +12 more
openaire   +2 more sources

Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury

open access: yesResearch, 2023
Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered a barrier for regeneration in the central nervous system.
Bolin Zheng   +8 more
doaj   +1 more source

Identification of immune cells infiltrating in hippocampus and key genes associated with Alzheimer’s disease

open access: yesBMC Medical Genomics, 2023
Alzheimer’s disease (AD) is the most prevalent cause of dementia and is primarily associated with memory impairment and cognitive decline, but the etiology of AD has not been elucidated. In recent years, evidence has shown that immune cells play critical
Chenming Liu   +5 more
doaj   +1 more source

Effects of Rubber Hand Illusion and Excitatory Theta Burst Stimulation on Tactile Sensation: A Pilot Study

open access: yesNeural Plasticity, 2020
Synchronous visuotactile stimulation on the own hidden hand and a visible fake limb can alter bodily self-perception and influence spontaneous neuroplasticity.
Vanessa N. Frey   +7 more
doaj   +1 more source

Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1

open access: yesDisease Models & Mechanisms, 2019
Tendon disorders frequently occur and recent evidence has clearly implicated the presence of immune cells and inflammatory events during early tendinopathy. However, the origin and properties of these cells remain poorly defined.
Christine Lehner   +9 more
doaj   +1 more source

Single collateral reconstructions reveal distinct phases of corticospinal remodeling after spinal cord injury. [PDF]

open access: yes, 2012
Injuries to the spinal cord often result in severe functional deficits that, in case of incomplete injuries, can be partially compensated by axonal remodeling.
Bareyre Florence M.   +11 more
core   +1 more source

Global Responses of Il-1β-Primed 3D Tendon Constructs to Treatment with Pulsed Electromagnetic Fields

open access: yesCells, 2019
Tendinopathy is accompanied by a cascade of inflammatory events promoting tendon degeneration. Among various cytokines, interleukin-1β plays a central role in driving catabolic processes, ultimately resulting in the activation of matrix ...
Renate Gehwolf   +8 more
doaj   +1 more source

A high-glucose diet affects Achilles tendon healing in rats

open access: yesScientific Reports, 2017
Chronic and acute tendinopathies are difficult to treat and tendon healing is generally a very slow and incomplete process and our general understanding of tendon biology and regeneration lags behind that of muscle or bone.
Stefanie Korntner   +10 more
doaj   +1 more source

Tendon vasculature in health and disease.

open access: yesFrontiers in Physiology, 2015
Tendons represent a bradytrophic tissue which is poorly vascularized and, compared to bone or skin, heal poorly. Usually, a vascularized connective scar tissue with inferior functional properties forms at the injury site.
Herbert eTempfer   +3 more
doaj   +1 more source

Nanofibrous Patches for Spinal Cord Regeneration [PDF]

open access: yesAdvanced Functional Materials, 2010
AbstractThe difficulty in spinal cord regeneration is related to the inhibitory factors for axon growth and the lack of appropriate axon guidance in the lesion region. Here scaffolds are developed with aligned nanofibers for nerve guidance and drug delivery in the spinal cord.
Yiqian, Zhu   +6 more
openaire   +2 more sources

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