Results 21 to 30 of about 542,273 (348)

The Nuclear Mitotic Apparatus (NuMA) Protein: A Key Player for Nuclear Formation, Spindle Assembly, and Spindle Positioning

Frontiers in Cell and Developmental Biology, 2021
The nuclear mitotic apparatus (NuMA) protein is well conserved in vertebrates, and dynamically changes its subcellular localization from the interphase nucleus to the mitotic/meiotic spindle poles and the mitotic cell cortex.
Tomomi Kiyomitsu, Susan Boerner
doaj   +1 more source

Orderly assembly underpinning built-in asymmetry in the yeast centrosome duplication cycle requires cyclin-dependent kinase

eLife, 2020
Asymmetric astral microtubule organization drives the polarized orientation of the S. cerevisiae mitotic spindle and primes the invariant inheritance of the old spindle pole body (SPB, the yeast centrosome) by the bud.
Marco Geymonat, Qiuran Peng, Zhiang Guo, Zulin Yu, Jay R Unruh, Sue L Jaspersen, Marisa Segal   +6 more
doaj   +1 more source

The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals

eLife, 2022
Proteins associated with the spindle apparatus, a cytoskeletal structure that ensures the proper segregation of chromosomes during cell division, experienced an unusual number of amino acid substitutions in modern humans after the split from the ...
Stéphane Peyrégne, Janet Kelso, Benjamin M Peter, Svante Pääbo   +3 more
doaj   +1 more source

Modeling and mechanical perturbations reveal how spatially regulated anchorage gives rise to spatially distinct mechanics across the mammalian spindle

eLife, 2022
During cell division, the spindle generates force to move chromosomes. In mammals, microtubule bundles called kinetochore-fibers (k-fibers) attach to and segregate chromosomes. To do so, k-fibers must be robustly anchored to the dynamic spindle.
Pooja Suresh, Vahe Galstyan, Rob Phillips, Sophie Dumont   +3 more
doaj   +1 more source

DSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation. [PDF]

, 1996
We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the ...
Brady, B, CANDE, W. Zacheus, Foss, M, Wein, H   +3 more
core   +2 more sources

On the stability of high-speed milling with spindle speed variation [PDF]

, 2010
Spindle speed variation is a well-known technique to suppress regenerative machine tool vibrations, but it is usually considered to be effective only for low spindle speeds.
BP Mann, E Al-Regib, E Budak, E Solis, F Yang, Gilles Dessein, Grégoire Peigné, GS Duncan, H Paris, H Zhang, J Tlusty, J Tlusty, JS Sexton, JS Sexton, JS Sexton, Lionel Arnaud, M Zatarain, MA Davies, ML Campomanes, ND Sims, PV Bayly, R Radulescu, RPH Faassen, S Jayaram, S Sastry, S Seguy, S Seguy, S Smith, SA Tobias, SC Lin, SD Merdol, Sébastien Seguy, T Insperger, T Insperger, T Insperger, T Insperger, T Surmann, T Takemura, Tamás Insperger, TC Tsao, XH Long, Y Altintas, Y Altintas, Y Altintas   +43 more
core   +4 more sources

An investigation into reducing the spindle acceleration energy consumption of machine tools [PDF]

, 2016
Machine tools are widely used in the manufacturing industry, and consume large amount of energy. Spindle acceleration appears frequently while machine tools are working. It produces power peak which is highly energy intensive. As a result, a considerable
Jia, Shun, Liu, Ying, Lv, Jingxiang, Tang, Renzhong, Tang, Wangchujun, Zhang, Yingfeng   +5 more
core   +2 more sources

Reduction of the influence on machining surface caused by tool non-repeatable run-out of rolling bearing spindle for machine tools (Improvement of machining surface quality with an excitation system)

Nihon Kikai Gakkai ronbunshu, 2021
In recent years, the demands for mirror finishing by cutting have increased, because the surface quality requirement in die and mold has become severer. In order to realize mirror surface finish by cutting, it is necessary to reduce the influence of tool
Yuta SHOWA, Hayato YOSHIOKA
doaj   +1 more source

Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation

eLife, 2017
Following learning, increased coupling between spindle oscillations in the medial prefrontal cortex (mPFC) and ripple oscillations in the hippocampus is thought to underlie memory consolidation.
Frances Xia, Blake A Richards, Matthew M Tran, Sheena A Josselyn, Kaori Takehara-Nishiuchi, Paul W Frankland   +5 more
doaj   +1 more source

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. [PDF]

, 2015
Correct orientation of the mitotic spindle in stem cells underlies organogenesis. Spindle abnormalities correlate with cancer progression in germ line-derived tumors.
Bucko, Paula, Canton, David, Gelman, Irwin, Hehnly, Heidi, Langeberg, Lorene K, Ogier, Leah, Santana, L Fernando, Scott, John D, Wordeman, Linda   +8 more
core   +1 more source