Results 51 to 60 of about 412,161 (357)

Xorbiting the spindle [PDF]

open access: yesThe Journal of Cell Biology, 2006
The Xorbit microtubule-binding protein, say Hannak and Heald (page 19), keeps the spindle from getting away from its passenger DNA. Figure Dominant-negative Xorbit (green) results in short spindles and chromosome (blue) alignment defects. Xorbit is a spindle-localized microtubule plus-end binding protein whose loss causes defects in ...
openaire   +2 more sources

Spindle pole bodies [PDF]

open access: yesCurrent Biology, 2013
What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Christian Seybold, Elmar Schiebel
openaire   +3 more sources

Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]

open access: yes, 2017
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R.   +9 more
core   +2 more sources

Mechanotransduction in the muscle spindle [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2014
The focus of this review is on the principal sensory ending of the mammalian muscle spindle, known as the primary ending. The process of mechanosensory transduction in the primary ending is examined under five headings: (i) action potential responses to defined mechanical stimuli-representing the ending's input-output properties; (ii) the receptor ...
Bewick, Guy S., Banks, Robert W.
openaire   +5 more sources

Strong static magnetic field delayed the early development of zebrafish [PDF]

open access: yesOpen Biology, 2019
One of the major topics in magnetobiology is the biological effects of strong static magnetic field (SMF) on living organisms. However, there has been a paucity of the comprehensive study of the long-term effects of strong SMF on an animal's development.
Shuchao Ge   +6 more
doaj   +1 more source

Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest

open access: yesBMC Genetics, 2011
Background Metaphase cells have short spindles for efficient bi-orientation of chromosomes. The cohesin proteins hold sister chromatids together, creating Sister Chromatid Cohesion (SCC) that helps in the maintenance of short spindle lengths in metaphase.
Sanyal Kaustuv   +4 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Spindle configurations of skew lines

open access: yes, 2004
We prove a conjecture of Crapo and Penne which characterizes isotopy classes of skew configurations with spindle-structure. We use this result in order to define an invariant, spindle-genus, for spindle-configurations.
Borobia   +11 more
core   +2 more sources

A comparative study of using spindle motor power and eddy current for the detection of tool conditions in milling processes [PDF]

open access: yes, 2015
This paper investigates the use of the power of the driving motor of a CNC spindle in comparison to two perpendicular eddy current sensors for the detection of tool wear in milling processes. Monitoring the power through the current profile is a low cost
Abbass, JK, Al-Habaibeh, A
core   +1 more source

The elegans of spindle assembly [PDF]

open access: yesCellular and Molecular Life Sciences, 2010
The Caenorhabditis elegans one-cell embryo is a powerful system in which to study microtubule organization because this large cell assembles both meiotic and mitotic spindles within the same cytoplasm over the course of 1 h in a stereotypical manner. The fertilized oocyte assembles two consecutive acentrosomal meiotic spindles that function to reduce ...
Eileen T. O'Toole   +3 more
openaire   +3 more sources

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