Results 51 to 60 of about 534,301 (305)
Mechanisms of Mitotic Spindle Assembly.
Annual Review of Biochemistry, 2016 Life depends on cell proliferation and the accurate segregation of chromosomes, which are mediated by the microtubule (MT)-based mitotic spindle and ∼200 essential MT-associated proteins.
Sabine Petry
semanticscholar +1 more source
Components of the yeast spindle and spindle pole body. [PDF]
The Journal of cell biology, 1990 Yeast spindle pole bodies (SPBs) with attached nuclear microtubles were enriched approximately 600-fold from yeast cell extracts. 14 mAbs prepared against this enriched SPB fraction define at least three components of the SPB and spindle. Immunofluorescent staining of yeast cells showed that throughout the cell cycle two of the components (110 and 90 ...
Michael P. Rout, John V. Kilmartin
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LET-99 functions in the astral furrowing pathway, where it is required for myosin enrichment in the contractile ring. [PDF]
, 2017 The anaphase spindle determines the position of the cytokinesis furrow, such that the contractile ring assembles in an equatorial zone between the two spindle poles.
Price, Kari L, Rose, Lesilee S
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Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex
Nature Cell Biology, 2017 ASPM (known as Asp in fly and ASPM-1 in worm) is a microcephaly-associated protein family that regulates spindle architecture, but the underlying mechanism is poorly understood.
K. Jiang +10 more
semanticscholar +1 more source
Telocytes in neuromuscular spindles [PDF]
Journal of Cellular and Molecular Medicine, 2013 AbstractA new cell type named telocyte (TC) has recently been identified in various stromal tissues, including skeletal muscle interstitium. The aim of this study was to investigate by means of light (conventional and immunohistochemical procedures) and electron microscopy the presence of TCs in adult human neuromuscular spindles (NMSs) and lay the ...
Díaz-Flores, Lucio +4 more
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Latrunculin A delays anaphase onset in fission yeast by disrupting an ase1-independent pathway controlling mitotic spindle stability [PDF]
, 2008 It has been proposed previously that latrunculin A, an inhibitor of actin polymerization, delays the onset of anaphase by causing spindle misorientation in fission yeast.
Meadows, John C., Millar, Jonathan B. A.
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Meiotic spindle assembly and chromosome segregation in oocytes
Journal of Cell Biology, 2016 Centrosomes play a key role in organizing the microtubule spindle that separates chromosomes during mitosis. Bennabi et al. review how microtubule spindle formation and chromosomal segregation also occur in oocytes during cell division by meiosis despite
Isma Bennabi, M. Terret, M. Verlhac
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Completion of the first meiosis is an essential prerequisite for producing a functionally normal egg for fertilization and embryogenesis, but the precise mechanisms governing oocyte meiotic progression remains largely unclear.
Hong Yin +12 more
doaj +1 more source
SciPost PhysicsWe study the spindle compactification of families of AdS_55 consistent truncations corresponding to M5 branes wrapped on complex curves in Calabi-Yau three-folds. From the AdS/CFT correspondence these models are dual to \mathcal{N}=1𝒩=1 SCFTs obtained by gluing of T_NTN blocks.
Amariti, Antonio +4 more
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Current Biology, 2013 What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Christian Seybold, Elmar Schiebel
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