Results 51 to 60 of about 542,273 (348)

Live cell imaging of meiosis in Arabidopsis thaliana

eLife, 2019
To follow the dynamics of meiosis in the model plant Arabidopsis, we have established a live cell imaging setup to observe male meiocytes. Our method is based on the concomitant visualization of microtubules (MTs) and a meiotic cohesin subunit that ...
Maria A Prusicki, Emma M Keizer, Rik P van Rosmalen, Shinichiro Komaki, Felix Seifert, Katja Müller, Erik Wijnker, Christian Fleck, Arp Schnittger   +8 more
doaj   +1 more source

TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]

, 2015
The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi, Chen, Pin-Hsi, Hwang, Tom, Nelson, Christian R   +3 more
core   +1 more source

Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast

Nature Communications, 2017
Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein.
Sergio A. Rincon, Adam R. Lamson, R. Blackwell, Viktoriya Syrovatkina, V. Fraisier, Anne Paoletti, M. Betterton, P. Tran   +7 more
semanticscholar   +1 more source

PREDICTION THE EVOLUTION OF TEMPERATURE AND VIBRATIONS ON SPINDLE USING ARTIFICIAL NEURAL NETWORKS AND FUZZY LOGIC [PDF]

Annals: Series on engineering sciences (Academy of Romanian Scientists), 2016
Simulation spindle behavior in terms of temperature and vibration at higher speeds is more economical and more secure (avoid undesirable mechanical events) than testing practice.
Daniel Petru GHENCEA, Miron ZAPCIU, Claudiu Florinel BISU   +2 more
doaj  

Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes [PDF]

, 2013
We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation.
Abe, Hiroshi, De Bock, Pieter-Jan, Fujiki, Saburo, Gevaert, Kris, Iwase, Shohei, Kuchitsu, Miyako, Ono, Shoichiro, Sato, Ryuhei, Tawada, Toshinobu, Yamagishi, Yuka   +9 more
core   +1 more source

Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

eLife, 2020
The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study.
Christopher Edelmaier, Adam R Lamson, Zachary R Gergely, Saad Ansari, Robert Blackwell, J Richard McIntosh, Matthew A Glaser, Meredith D Betterton   +7 more
doaj   +1 more source

Pericentric major satellite transcription is essential for meiotic chromosome stability and spindle pole organization

Open Biology, 2023
In somatic cells, mitotic transcription of major satellite non-coding RNAs is tightly regulated and essential for heterochromatin formation and the maintenance of genome integrity.
Claudia Baumann, Xiangyu Zhang, Maria M. Viveiros, Rabindranath De La Fuente   +3 more
doaj   +1 more source

Study on the 2D Equivalent Simulation Model of Bearing and Spindle for Precision Machine Tools

Machines, 2023
Precision spindle and bearings are the key components in precision machine tools. These structures greatly affect the machining accuracy and service life of the machine tools.
Shijun Xiu, Jibo Li, Xiangjun Chen, Yifan Xia, Pei Wang   +4 more
doaj   +1 more source

Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]

, 2017
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R., Bryant, David M., Gao, Lei, Hiremath, Chitkale, Long, Blake, Luby-Phelps, Katherine, Marciano, Denise K., Mostov, Keith E., Yang, Zhufeng, Zimmerman, Susan E.   +9 more
core   +2 more sources

Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans

Journal of Neuroscience, 1995
The role of the endogenous circadian pacemaker in the timing of the sleep-wake cycle and the regulation of the internal structure of sleep, including REM sleep, EEG slow-wave (0.75–4.5 Hz) and sleep spindle activity (12.75–15.0 Hz) was investigated ...
Dj Dijk, C. Czeisler
semanticscholar   +1 more source