Plasmodium berghei Kinesin-5 Associates With the Spindle Apparatus During Cell Division and Is Important for Efficient Production of Infectious Sporozoites [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Kinesin-5 motors play essential roles in spindle apparatus assembly during cell division, by generating forces to establish and maintain the spindle bipolarity essential for proper chromosome segregation.
Mohammad Zeeshan +5 more
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The Nuclear Mitotic Apparatus (NuMA) Protein: A Key Player for Nuclear Formation, Spindle Assembly, and Spindle Positioning [PDF]
Frontiers in Cell and Developmental Biology, 2021 The nuclear mitotic apparatus (NuMA) protein is well conserved in vertebrates, and dynamically changes its subcellular localization from the interphase nucleus to the mitotic/meiotic spindle poles and the mitotic cell cortex.
Tomomi Kiyomitsu, Susan Boerner
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A case of oculomotor nerve palsy associated with antimitotic spindle apparatus
Clinical Ophthalmology, 2011 Jong Jin Jung, Ungsoo Samuel KimDepartment of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, KoreaAbstract: In this case report, we describe a case of isolated oculomotor nerve palsy associated with antibodies ...
Kim US, Jung JJ
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Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1) [PDF]
Cancer Cell International, 2022 Background The function of spindle apparatus coiled-coil protein 1 (SPDL1) as a cancer-promoting gene has been reported in a number of studies. However, the pan-cancer analysis of SPDL1 is still lacking.
Peng Song +7 more
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Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length [PDF]
Advanced ScienceThe cytoskeleton is composed of microtubules, microfilaments, and intermediate filaments in cells. While the functions of microtubules and microfilaments have been well elucidated, the roles of intermediate filaments and associated proteins remain ...
Yu Li +6 more
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eLife, 2023 WDR62 is a spindle pole-associated scaffold protein with pleiotropic functions. Recessive mutations in WDR62 cause structural brain abnormalities and account for the second most common cause of autosomal recessive primary microcephaly (MCPH), indicating ...
Claudia Dell'Amico +9 more
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Application of collagen triple helix repeat containing-1 and mitotic spindle apparatus antibody in small cell lung cancer diagnosis. [PDF]
J Clin Lab Anal, 2022 Liu Y +7 more
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Uncommon patterns of antinuclear antibodies recognizing mitotic spindle apparatus antigens and clinical associations. [PDF]
Medicine (Baltimore), 2018 Betancur JF +7 more
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The post-translational modification of NuMA in cancer cells is a new target for cancer eradication [PDF]
Cell Death and DiseaseRecent findings identify a cell-death mechanism in human cancer cells, based on the inhibition of the post-translational modification of NuMA (nuclear mitotic apparatus protein) in cancer cells, which interferes with its protein-binding capacity. NuMA is
Malka Cohen-Armon
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Silencing of spindle apparatus coiled-coil protein 1 suppressed the progression of hepatocellular carcinoma through farnesyltransferase-beta and increased drug sensitivity. [PDF]
HeliyonZhai Y +10 more
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