Results 171 to 180 of about 1,379,565 (255)

Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship. [PDF]

Cell Cycle
Pleuger R, Westermann S.
europepmc   +1 more source

Information‐Theoretic Framework for Allosteric Communication Pathway Prediction From Protein Structure

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Allosteric communication is fundamental to the function of proteins, but identifying the residue‐level pathways through which signals travel and their directionality is still a major challenge. Here we present a multi‐metric information‐theoretic framework that identifies candidate allosteric communication pathways from a single protein ...
Aysima Hacisuleyman, Dirk Fasshauer
wiley   +1 more source

hSpindly dynamics modulate spindle assembly checkpoint signaling, promoting resistance to mitotic inhibitors. [PDF]

iScience
Mora-Santos M, Herrero-Ruiz J, Fennema-Galparsoro D, Belmonte-Fernández A, Ferrandiz N, Romero F.   +5 more
europepmc   +1 more source

Comprehensive analysis of microtubule‐inhibiting herbicides reveals shared subcellular phenotypes and distinct resistance profiles

Pest Management Science, EarlyView.
Using cellular phenotyping and resistance profiling, we show that herbicides across the Herbicide Resistance Action Committee (HRAC) Groups 3 and 23 induce indistinguishable, dose‐dependent microtubule defects. Resistance patterns, rather than cellular phenotypes, reveal distinct sites of action and support reclassifying Group 3 as α‐tubulin binders ...
Katharina Kaprocki, Jennifer Blau, Michael Betz, Jessica Knox, Jens Lerchl, Philipp Johnen, Selene Garcia‐Hernandez   +6 more
wiley   +1 more source

Correction: PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression. [PDF]

Sci Rep
Teye EK, Lu S, Chen F, Yang W, Abraham T, Stairs DB, Wang HG, Yochum GS, Brodsky RA, Pu JJ.   +9 more
europepmc   +1 more source

Recent Advances in Oriented Hydrogels: From Fundamental Mechanisms to Future Challenges

SusMat, EarlyView.
Traditional hydrogels suffer from weak mechanical properties and limited functionality due to their random polymer networks. This review comprehensively summarizes the reinforcement mechanisms of oriented structure for hydrogels, the design/fabrication strategies, and the latest application progress of high‐strength oriented hydrogels.
Chang Xu, Xijing Zhuang
wiley   +1 more source

Modelling of dynamical behavior of a spindle-holder-tool assembly

, 2012
This paper describes the complete procedure for mathematical modeling of dynamic behavior of a spindle - holder - tool assembly. The developed model, in addition to translational, takes into account the rotational degrees of freedom, and therefore can be
Zeljković, Milan, Čiča D., Globočki-Lakić G., Sredanović B.   +3 more
core  

Hyaluronan‐Mediated Motility Receptor Potentiates Colorectal Carcinoma Progression Through PI3K/AKT/mTOR Pathway Modulation

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Hyaluronan‐mediated motility receptor (HMMR) promotes colorectal cancer progression by enhancing proliferation, migration, and invasion through activation of the PI3K/AKT/mTOR pathway. Targeting HMMR effectively suppresses these malignant phenotypes, highlighting its potential as a promising therapeutic target in colorectal carcinoma.
Cheng Shi, Yu Chen, Xinyu Hu, Fujin Jin, Qi Liu, Chongbin Ou, Yecai Lu   +6 more
wiley   +1 more source

Optochemical elucidation of a critical role of the incomplete spindle assembly checkpoint in zebrafish development. [PDF]

Commun Biol
Matsura A, Hosono M, Matsuo K, Tamaoki N, Kotani T, Uehara R.   +5 more
europepmc   +1 more source

Between Gaps and Voids: An Archaeometrical Study of Degraded Fibers in a Sherd From the Cueva dos Chinches Muertas, Siltzul (Raxruha, Alta Verapaz, Guatemala)

Archaeometry, EarlyView.
ABSTRACT In 2019, excavations at the Cueva dos Chinches Muertas carried out by the Raxruha Viejo Project uncovered a small ceramic sherd distinguished by a stratified structure composed of multiple layers of textile imprints, both superficial and transversal.
Marie Ramelet
wiley   +1 more source