Results 161 to 170 of about 58,631 (285)

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source

The role of fission yeast nuclear actin-related protein in mitosis. [PDF]

, 2005
Nuclear actin-related proteins (Arps) have 20-30% identity to conventional actin and many are found to be in chromatin remodelling complexes. There are two families of chromatin remodelling complexes, one of which carries out covalent modification on ...
Minoda, A., Minoda, Akiko
core  

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

Nano‐Engineered Basalt Fiber Composites With Halloysite Nanotubes: Durability and Drilling Behavior After Acidic Aging

Polymer Composites, EarlyView.
Schematic summary of the drilling damage and microstructural degradation mechanisms in basalt fiber‐reinforced composites after acidic aging. ABSTRACT This study investigates the drilling performance and environmental durability of basalt fiber reinforced polymer (BRC) and halloysite nanotube (HNT) modified basalt nanocomposites (BRnC) exposed to ...
İbrahim Aslan, Harun Yaka, Hasan Ulus, Halil Burak Kaybal   +3 more
wiley   +1 more source

Curling Suppression by Adhesive Tape Enables Direct Processing of Thin Polymer Strips

Polymer Engineering &Science, EarlyView.
Machining‐based approch for processing of polymer strip: A simple adhesive tape applied to the workpiece surface suppresses severe chip curling, enabling the single‐step production of flat, straight polymer strips. ABSTRACT Thin polymer strips and films are critical components in flexible electronics, packaging, and energy storage systems, yet their ...
Debapriya Pinaki Mohanty, Shuta Tsuji, Toshiyuki Enomoto, Tatsuya Sugihara   +3 more
wiley   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Actuation Strategies for Underwater Jet‐Propelled Soft Robots

Journal of Field Robotics, EarlyView.
ABSTRACT This review article examines jet‐propulsion mechanisms in underwater soft robotic systems, focusing exclusively on physically fabricated and experimentally validated robots. Covering research published from 2013 to 2025, this study classifies and evaluates jet‐propulsion robots based on their actuation mechanisms.
Angel Kitone, Mohammed Anteet, Pawandeep S. Matharu, Yara Almubarak   +3 more
wiley   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

Small, EarlyView.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova, Olivera Valentirović Dann, Jennifer B. Schwarzkopf, Tengku I. Maulana, Jamina S. Gerhardus, Leon Kaysan, Katja Meier, Andreas Blaeser, Beate K. Straub, Holger Gerhardt, Ulrike A. Nuber   +10 more
wiley   +1 more source

Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy. [PDF]

Elife
Koch LB, Ghosh T, Spanos C, Marston AL.
europepmc   +2 more sources