Results 141 to 150 of about 51,274 (213)

Nicotinamide mononucleotide biosynthesis and the F-actin cytoskeleton regulate spindle assembly and oocyte maturation quality in post-ovulatory aged porcine oocytes. [PDF]

Cell Commun Signal
Park HJ, Yang SG, Shin JH, Yoon SB, Kim JS, Koo DB.   +5 more
europepmc   +1 more source

CDC20 determines the sensitivity to spindle assembly checkpoint (SAC) inhibitors

, 2023
Zheng S, Raz L, Zhou L, Cohen-Sharir Y, Tian R, Wardenaar R, Broekhuis M, Rodriguez MSP, Wobben S, van den Brink A, Bakker P, Foijer F, David U.   +12 more
europepmc   +1 more source

Cell Membrane Vesicles Encapsulating Il24 mRNA With Enriched CD6 Display Exhibit Enhanced Targeted Antitumor Efficacy

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT mRNA‐based therapeutics offer significant potential for cancer treatment owing to their ability to induce transient, non‐integrating expression of therapeutic proteins. However, effective and tumour‐specific delivery remains a major barrier.
Dandan Wang, Ruofan Gao, Duo Liu, Kefan Li, Runkai Wang, Minghe Xu, Shiwei Zhang, Shengjie Jiang, Bin Xia   +8 more
wiley   +1 more source

Revisiting the role of the spindle assembly checkpoint in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae. [PDF]

Genetics
Yao Y, Yin Z, Rosas Bringas FR, Boudeman J, Novarina D, Chang M.   +5 more
europepmc   +1 more source

Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly

Journal of Mass Spectrometry, Volume 61, Issue 6, June 2026.
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede, Anisha Haris, Tomislav Damjanović, Jocky C. K. Kung, Jürgen Müller‐Guhl, Ronja Pogan, Jennifer Rothe, Wiebke Schultze, Sanne Ugelstad, David Eatough, Kevin Giles, Steve Preece, Keith Richardson, Jakub Ujma, Charlotte Uetrecht   +14 more
wiley   +1 more source

The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans. [PDF]

PLoS Genet
Polisetty SD, Bhat K, Das K, Clark I, Hardwick KG, Sanyal K.   +5 more
europepmc   +1 more source

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli, Thatipally Rajeshwar, Sarad Pawar Naik Bukke   +2 more
wiley   +1 more source

Liquid-liquid phase separation of microtubule-binding proteins in the regulation of spindle assembly. [PDF]

Cell Prolif
Sun S, Yang Y, Zhou J, Liu P.
europepmc   +1 more source

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

NSC632839 suppresses esophageal squamous cell carcinoma cell proliferation in vitro by triggering spindle assembly checkpoint-mediated mitotic arrest and CREB-Noxa-dependent apoptosis. [PDF]

Cancer Cell Int
Zhao S, Dong G, Guo Y, Sun Y, Li M, Sha B, Huang W, Zhang Y, Du Y, Yan J, Ma Y, Yang R, Shi J, Li P, Hu T, Chen P.   +15 more
europepmc   +1 more source