Results 141 to 150 of about 1,379,565 (255)

A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes.

open access: yes, 2019
Mammalian oocytes segregate chromosomes with a microtubule spindle that lacks centrosomes, but the mechanisms by which acentrosomal spindles are organized and function are largely unclear.
Seres, B.   +17 more
core   +1 more source

Scaffold‐Free Living Cellular Structure With Omnidirectional Architectures

open access: yesAdvanced NanoBiomed Research, EarlyView.
Hydrogel lumen confinement enables the direct formation of mechanically stable, scaffold‐free cellular filaments under entirely aqueous, phototoxicity‐free conditions. These processable living building blocks support omnidirectional assembly into complex three‐dimensional architectures, providing a simple and versatile platform for scaffold‐free ...
Jing Ma   +7 more
wiley   +1 more source

Compliant hydrogel cuff coating with real‐time pressure monitoring and antibiofilm capabilities for ventilator‐associated pneumonia prophylaxis

open access: yesBMEMat, EarlyView.
A soft‐compliant hydrogel cuff coating combines real‐time pressure monitoring with intrinsic antibacterial activity for prophylaxis of ventilator‐associated pneumonia. A flexible pressure‐sensing patch is embedded in the coating to enable wireless dynamic monitoring of endotracheal cuff pressure through Bluetooth.
Jin Chai   +11 more
wiley   +1 more source

Substrate stiffness regulates cell fate and its applications in the repair of motor system: From two dimensions to three dimensions

open access: yesBMEMat, EarlyView.
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu   +6 more
wiley   +1 more source

Carbon‐Embedded Fe‐Cu Composite Oxide Nanoparticles Derived From Spindle‐Shaped Bimetallic MOFs for Selective Oxidation of Methane

open access: yesCarbon and Hydrogen, EarlyView.
Fe3Cu1/C (CuFe5O8) was synthesized by high‐temperature carbonization of FexCuyBDC MOF, which exhibited excellent catalytic performance for methane selective oxidation at 80°C. The synergistic effect between Cu and Fe in the derived Fe3Cu1/C (CuFe5O8) composite oxide inhibits deep oxidation compare to Fe/C (Fe3O4), and the reaction proceeds via a free ...
Jiaxin Cai   +7 more
wiley   +1 more source

Research Progress on V2CTx MXene‐Based Composites: Synthetic Strategies, Structure Design, and Multifunctional Applications

open access: yesCarbon Energy, EarlyView.
This review systematically and comprehensively summarizes the latest research progress on V2CTx MXene. Focusing on the structural design strategies, particularly the construction of the V2CTx‐based hetero‐composite structure. Furthermore, widespread applications including electrochemical energy storage and conversion, as well as photocatalytic ...
Wenjun Zhu   +9 more
wiley   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius   +6 more
wiley   +1 more source

Spindle Assembly Factors Cooperatively Regulate Bridging Microtubules

open access: yes
The chromosome-based Ran–GTP gradient activates a set of spindle assembly factors during mitosis. These microtubule-associated proteins individually regulate spindle pole focusing, microtubule branching, kinetochore fibre stabilization, and polar ...
Cedric Castrogiovanni   +3 more
core   +1 more source

Microtubule Destabilizing Kinesins: A Historical Perspective and Thoughts for the Future

open access: yesCytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton plays critical roles in multiple cellular processes such as mitotic spindle assembly and chromosome segregation. Cells contain a number of microtubule‐associated proteins that regulate microtubule dynamics both temporally and spatially in cells. The microtubule depolymerizing kinesins include members of the Kinesin‐
Claire E. Walczak
wiley   +1 more source

Assembly and Maintenance of Myofibrils in the Heart

open access: yesCytoskeleton, EarlyView.
ABSTRACT The assembly of actin and myosin to the paracrystalline arrangement of myofibrils in striated muscle, that is, heart and skeletal, has puzzled many a cell biologist. Different models, based on cultured cardiomyocytes, were proposed for the last 30 years to explain the sequence of events.
Elisabeth Ehler
wiley   +1 more source

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