Results 121 to 130 of about 51,274 (213)

TTK Overexpression: A Negative Prognostic Biomarker in Anaplastic Thyroid Carcinoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Given threonine and tyrosine kinase (TTK)'s oncogenic role in various cancers and its understudied status in thyroid cancer, this study investigates TTK expression in thyroid lesions to assess its diagnostic and therapeutic potential. Methods We analyzed differential TTK expression levels using public datasets (n = 143) and clinical
Yan Guo, Zhidong Sun, Xiao Liu, Xianni Liu, Haiwen Chen, Menglan Zhang, Weibo Mao, Yuan Cao   +7 more
wiley   +1 more source

The cohesin-associated protein Pds5A governs the meiotic spindle assembly via deubiquitination of Kif5B in oocytes. [PDF]

Sci Adv
Zhang Y, Bai J, Xiong B.
europepmc   +1 more source

Docetaxel‐Induced Serositis Mimicking Malignant Pleural Effusion

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pleural effusions are common in patients with cancer. Although their development may signal progressive malignant disease, drug‐induced effusions are a rare and often overlooked cause of exudative pleural effusions. We describe a 50‐year‐old woman with recurrent granulosa cell tumor of the ovary who developed bilateral pleural and pericardial ...
Muhammad Anees, Kevin Chiu, Stephen Goertzen, Carlos A. Jimenez, Saadia A. Faiz   +4 more
wiley   +1 more source

A Microtubule-Associated Protein Functions in Preventing Oocytes from Evading the Spindle Assembly Checkpoint. [PDF]

Adv Sci (Weinh)
Zhou C, Zhang X, Xu G, Ran Y, Wang H, Xie X, Li A, Li F, Li X, Ding J, Zhang M, Sun QY, Ou XH.   +12 more
europepmc   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, Volume 83, Issue 6, Page 328-336, June 2026.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

Dynamics of spindle assembly and position checkpoints: Integrating molecular mechanisms with computational models. [PDF]

Comput Struct Biotechnol J
Ibrahim B.
europepmc   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, Volume 83, Issue 6, Page 337-353, June 2026.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana , many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Evolutionary adaptation to hyperstable microtubules selectively targets tubulins and is empowered by the spindle assembly checkpoint. [PDF]

Cell Rep
Macaluso F, Bos T, Chiroli E, Bonaiuti P, Apuan JC, Gross F, Pompei S, Rice LM, Ciliberto A.   +8 more
europepmc   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, Volume 83, Issue 6, Page 354-375, June 2026.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Arabidopsis KNL1 recruits type one protein phosphatase to kinetochores to silence the spindle assembly checkpoint. [PDF]

Sci Adv
He Y, Tang X, Fu H, Tang Y, Lin H, Deng X.   +5 more
europepmc   +1 more source