Results 101 to 110 of about 58,631 (285)

Initial Characterization of two novel spindle proteins, CHICA and HURP [PDF]

, 2008
During mitotic spindle assembly, the sister chromatids have to be captured by kinetochore (K) -fibers (bundles of kinetochore microtubules; KMTs) to ensure stable attachment of the chromosomes.
Nagel, Susanna
core  

Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry. [PDF]

, 2015
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Rosa, André, Pichaud, Franck, Vlassaks, E, Baum, B, Pichaud, F, Rosa, A, Vlassaks, Evi, Baum, Buzz   +7 more
core   +1 more source

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

Advanced Science
As a major component of the cytoskeleton, intermediate filaments are generally considered to play a supporting role in mitotic cells. They also take part in the regulation of cell motility, proliferation, differentiation, and apoptosis.
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
doaj   +1 more source

Water‐Enabled Ultralong Full‐Color Organic Phosphorescence in Hydrogen‐Bonded Frameworks for 4D Encryption and Bio‐Imaging

Advanced Science, EarlyView.
Water‐induced quenching challenges organic RTP materials, but a counter‐intuitive strategy employs HOF to encapsulate carbonyl guests, where water functions as a structural reinforcer. This achieves water‐enhanced ultralong RTP with full‐color emission (blue to deep red), overcoming intracellular quenching for high‐signal cellular imaging, alongside 4D
Pengcheng Wu, Zenggang Lin, Lu Yang, Weisheng Liu   +3 more
wiley   +1 more source

The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo [PDF]

, 2002
In all eukaryotic organisms, the physical separation of two nascent cells must be coordinated with chromosome segregation and mitotic exit. In Saccharomyces cerevisiae and Schizosaccharomyces pombe this coordination depends on a number of genes that ...
Erich A. Nigg, Gartner, A., Nigg, EA, Glotzer, Michael, Gruneberg, Ulrike, Nigg, E. A., Michael Glotzer, Gartner, A, Gruneberg, U, Ulrike Gruneberg, Nigg, Erich A., Glotzer, M., Anton Gartner, Glotzer, M, Grüneberg, U., Gartner, Anton   +15 more
core   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

Investigation into how mitotic spindle checkpoint function is compromised by Sv40 large T antigen. [PDF]

, 2005
The viral oncoprotein Simian virus 40 large T antigen (LT) efficiently immortalises primary rodent cells and occasionally transforms them to tumourigenicity.
Lock, Rowena Lesley, Lock, R.L.
core  

Phase Transition of Spindle-Associated Protein Regulate Spindle Apparatus Assembly [PDF]

, 2015
SummarySpindle assembly required during mitosis depends on microtubule polymerization. We demonstrate that the evolutionarily conserved low-complexity protein, BuGZ, undergoes phase transition or coacervation to promote assembly of both spindles and ...
Wang, Shusheng, Cui, Honggang, Zheng, Yixian, He, Xiaonan, Zhu, Xueliang, Jiang, Hao, Huang, Yuejia   +6 more
core   +1 more source

Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes.

PLoS Genetics, 2015
In oocytes, where centrosomes are absent, the chromosomes direct the assembly of a bipolar spindle. Interactions between chromosomes and microtubules are essential for both spindle formation and chromosome segregation, but the nature and function of ...
Sarah J Radford, Tranchau L Hoang, A Agata Głuszek, Hiroyuki Ohkura, Kim S McKim   +4 more
doaj   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

Advanced Science, EarlyView.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu, Yalin Liu, Rongyi Wang, Wenwen Xu, Hao Shi, Ning Huang, Junlin Teng, Jin Meng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source