Results 261 to 270 of about 58,631 (285)

Spatial gradients controlling spindle assembly

Biochemical Society Transactions, 2015
The mitotic spindle is the macromolecular machine utilized to accurately segregate chromosomes in cells. How this self-organized structure assembles is a key aspect of understanding spindle morphogenesis. In the present review, we focus on understanding mechanisms of spindle self-assembly and address how subcellular signalling gradients, such as Ran ...
Lesley N, Weaver, Claire E, Walczak
openaire   +2 more sources

Mechanisms of Mitotic Spindle Assembly and Function

2008
The mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major structural elements of the spindle are microtubule polymers, whose intrinsic polarity and dynamic properties are critical for bipolar spindle organization and function.
Claire E, Walczak, Rebecca, Heald
openaire   +2 more sources

The spindle assembly checkpoint in budding yeast

1997
Publisher Summary This chapter discusses the spindle assembly checkpoint in budding yeast. As cells proceed through cycles of growth and division they are often challenged by environmental insult and injury as well as spontaneous errors in cellular processes. The response to cell damage requires that cells sense the damage, arrest the cell cycle, and
A F, Straight, A W, Murray
openaire   +2 more sources

Apoptosis and spindle-assembly united

Trends in Cell Biology, 1999
openaire   +2 more sources

Mitotic spindle assembly in animal cells: a fine balancing act

Nature Reviews Molecular Cell Biology, 2017
SUZANNA Prosser, Laurence Pelletier, Prosser SUZANNA L   +2 more
exaly  

Microtubules protect spindle assembly factors

Nature Reviews Molecular Cell Biology, 2014
Katharine H Wrighton, Wrighton Katharine H   +1 more
exaly  

Dissecting the role of Aurora A during spindle assembly

EMBO Journal, 2008
Boryana Petrova, Isabelle Vernos
exaly  

TRIP13 Functions in the Establishment of the Spindle Assembly Checkpoint by Replenishing O-MAD2

Cell Reports, 2018
Randy Y C Poon, Ma Hoi Tang
exaly  

OsMTOPVIB is required for meiotic bipolar spindle assembly

Proceedings of the National Academy of Sciences of the United States of America, 2019
Qiang Ge, Yi Shen, Zhukuan Cheng
exaly  

Ablation of the spindle assembly checkpoint by a compound targeting Mps1

EMBO Reports, 2005
Marc Schmidt, Rob Klompmaker
exaly