Results 111 to 120 of about 4,116 (226)
The spindle checkpoint and chromosome segregation in meiosis [PDF]
The FEBS Journal, 2015 The spindle checkpoint is a key regulator of chromosome segregation in mitosis and meiosis. Its function is to prevent precocious anaphase onset before chromosomes have achieved bipolar attachment to the spindle. The spindle checkpoint comprises a complex set of signaling pathways that integrate microtubule dynamics, biomechanical forces at the ...
openaire +2 more sources
Microscopy Research and Technique, EarlyView.ABSTRACT Haloxyfop‐R‐methyl (HRM) is extensively employed to control annual and perennial grass weeds. This study aimed to investigate the cyto‐genotoxic effects of HRM at concentrations of 1.19, 2.38, and 4.76 mg/L over various time intervals (24, 48, 72, and 96 h) on Allium cepa root.
Recep Liman +4 more
wiley +1 more source
Journal of the Formosan Medical Association, 2009 Aneuploidy is a major manifestation of chromosomal instability, which is defined as a numerical abnormality of chromosomes in diploid cells. It is highly prevalent in a variety of human malignancies. Increased chromosomal instability is the major driving
Wei Dai
doaj +1 more source
Logspace computations for Garside groups of spindle type [PDF]
arXiv, 2013 M. Picantin introduced the notion of Garside groups of spindle type, generalizing the 3-strand braid group. We show that, for linear Garside groups of spindle type, a normal form and a solution to the conjugacy problem are logspace computable. For linear Garside groups of spindle type with homogenous presentation we compute a geodesic normal form in ...
arxiv
ChemistryOpen, EarlyView.[1‐(Ethoxycarbonyl)cyclopropyl] triphenylphosphonium tetrafluoroborate is a limiting key reagent for synthesis of the tricyclic 5,6‐dihydropyrimido[5,4‐e]indolizine and related scaffolds, which are central to First‐in‐Class covalent inhibitors of the protein kinase monopolar spindle 1/threonine tyrosine kinase (TTK).
Leon Rebhan +4 more
wiley +1 more source
Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast [PDF]
arXiv, 2016 Kinesin-8 motor proteins destabilize microtubules. Their absence during cell division is associated with disorganized mitotic chromosome movements and chromosome loss. Despite recent work studying effects of kinesin 8s on microtubule dynamics, it remains unclear whether the kinesin-8 mitotic phenotypes are consequences of their effect on microtubule ...
arxiv
Molecular Ecology Resources, EarlyView.ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty +6 more
wiley +1 more source
Fission Yeast Bub1 Is a Mitotic Centromere Protein Essential for the Spindle Checkpoint and the Preservation of Correct Ploidy through Mitosis [PDF]
, 1998 Pascal Bernard +2 more
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Aging Cell, EarlyView.UVB exposure can trigger senescence in dermal fibroblasts. We show that silencing ATF6α disrupts the establishment of the UVB‐induced senescent phenotype by preventing the onset of several senescent biomarkers and altering the composition of the SASP, consequently affecting its impact on the skin microenvironment.
Joëlle Giroud +19 more
wiley +1 more source
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation [PDF]
, 2001 Bonnie J. Howell +6 more
openalex +3 more sources