Human Papillomavirus Oncoproteins E6 and E7 Independently Abrogate the Mitotic Spindle Checkpoint [PDF]
, 1998 Jennifer T. Thomas, Laimonis A. Laimins
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G3: Genes, Genomes, Genetics, 2017 Relatively little is known about the cross-talk between the spindle assembly checkpoint and the DNA damage response, especially in multicellular organisms.
Simone Bertolini +4 more
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The Bub2p Spindle Checkpoint Links Nuclear Migration with Mitotic Exit [PDF]
, 2000 Gislene Pereira
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Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities
Cell Proliferation, EarlyView.ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou +7 more
wiley +1 more source
Optimal Checkpointing for Secure Intermittently-Powered IoT Devices [PDF]
arXiv, 2017 Energy harvesting is a promising solution to power Internet of Things (IoT) devices. Due to the intermittent nature of these energy sources, one cannot guarantee forward progress of program execution. Prior work has advocated for checkpointing the intermediate state to off-chip non-volatile memory (NVM).
arxiv
Chromosomal Instability Syndrome of Total Premature Chromatid Separation with Mosaic Variegated Aneuploidy Is Defective in Mitotic-Spindle Checkpoint [PDF]
, 2000 Shinya Matsuura +5 more
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The Prognostic Significance of Tumoral Melanosis
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background Tumoral melanosis (TM) is a histological term to describe a nodular aggregation of macrophages containing melanin pigment (melanophages) that is devoid of viable melanocytes. It is most often identified in skin, where it may be appreciated clinically as a pigmented lesion; however, it can also be found in other organs such as lymph ...
Alison J. Potter +7 more
wiley +1 more source
Dual Targeting of Pim and PI3 Kinases in Mature T‐Cell Lymphoma
European Journal of Haematology, EarlyView.ABSTRACT Provirus Integration site for Moloney leukemia virus (Pim) family members are well‐known oncogenes, with an expression that is restricted to few cell types including hematopoietic cells in adult organisms, making it a promising target for lymphoma treatment.
M. Lohrberg +13 more
wiley +1 more source
PLoS Genetics, 2016 The spindle checkpoint is a mitotic surveillance system which ensures equal segregation of sister chromatids. It delays anaphase onset by inhibiting the action of the E3 ubiquitin ligase known as the anaphase promoting complex or cyclosome (APC/C).
Judith Zich +11 more
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A Human REV7 Homolog That Interacts with the Polymerase ζ Catalytic Subunit hREV3 and the Spindle Assembly Checkpoint Protein hMAD2 [PDF]
, 2000 Yoshiki Murakumo +6 more
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