Results 41 to 50 of about 29,426 (187)
Illuminating spindle convex bodies and minimizing the volume of spherical sets of constant width [PDF]
Discrete and Computational Geometry 47/2 (2012), 275-287, 2011 A subset of the d-dimensional Euclidean space having nonempty interior is called a spindle convex body if it is the intersection of (finitely or infinitely many) congruent d-dimensional closed balls. The spindle convex body is called a "fat" one, if it contains the centers of its generating balls.
arxiv +1 more source
TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching
eLife, 2015 The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Qiaozhen Ye +5 more
doaj +1 more source
Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis. [PDF]
PLoS Genetics, 2007 During cell division all chromosomes must be segregated accurately to each daughter cell. Errors in this process give rise to aneuploidy, which leads to birth defects and is implicated in cancer progression.
Josefin Fernius, Kevin G Hardwick
doaj +1 more source
Spindle configurations of skew lines [PDF]
Geom. Topol. 11 (2007) 1049-1081, 2002 We prove a conjecture of Crapo and Penne which characterizes isotopy classes of skew configurations with spindle-structure. We use this result in order to define an invariant, spindle-genus, for spindle-configurations. We also slightly simplify the exposition of some known invariants for configurations of skew lines and use them to define a natural ...
arxiv +1 more source
Frontiers in Physiology, 2021 Mitosis proceeds through a defined series of events that is largely conserved, but the amount of time needed for their completion can vary in different cells and organisms.
Mathew Bloomfield +2 more
doaj +1 more source
On-off intermittency of thalamo-cortical oscillations in the electroencephalogram of rats with genetic predisposition to absence epilepsy [PDF]
Brain research. 1436 (2012) 147-156, 2013 Spike-wave discharges (SWD) are electroencephalographic hallmarks of absence epilepsy. SWD are known to originate from thalamo-cortical neuronal network that normally produce sleep spindle oscillations. Although both sleep spindles and SWD are considered as thalamo-cortical oscillations, functional relationship between them is still uncertain.
arxiv +1 more source
Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint
Cells, 2015 The segregation of the chromosomes during mitosis is an important process, in which the replicated DNA content is properly allocated into two daughter cells.
Ikram Mossaid, Birthe Fahrenkrog
doaj +1 more source
Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint. [PDF]
PLoS ONE, 2007 Mitotic progression is controlled by proteolytic destruction of securin and cyclin. The mitotic E3 ubiquitin ligase, known as the anaphase promoting complex or cyclosome (APC/C), in partnership with its activators Cdc20p and Cdh1p, targets these proteins
Emma M J King +2 more
doaj +1 more source
Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
Nature Communications, 2017 The spindle assembly checkpoint delays mitotic progression until sister chromatids are bi-oriented. Here the authors show that moderate delays in mitotic progression induce centrosome fragmentation and centriole disengagement and that spindle bipolarity ...
Menuka Karki +2 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2008 CHFR is an E3 ubiquitin ligase and an early mitotic checkpoint protein implicated in many cancers and in the maintenance of genomic stability. To analyze the role of CHFR in genomic stability, by siRNA, we decreased its expression in genomically stable ...
Lisa M. Privette +4 more
doaj +1 more source