Results 51 to 60 of about 29,426 (187)
A novel role for the GTPase-activating protein Bud2 in the spindle position checkpoint. [PDF]
PLoS ONE, 2012 The spindle position checkpoint (SPC) ensures correct mitotic spindle position before allowing mitotic exit in the budding yeast Saccharomyces cerevisiae. In a candidate screen for checkpoint genes, we identified bud2Δ as deficient for the SPC. Bud2 is a
Scott A Nelson +3 more
doaj +1 more source
Human kinetochores are swivel joints that mediate microtubule attachments
eLife, 2016 Chromosome segregation is a mechanical process that requires assembly of the mitotic spindle – a dynamic microtubule-based force-generating machine.
Chris A Smith +2 more
doaj +1 more source
Hydrodynamic mechanism for stable spindle positioning in meiosis II oocytes [PDF]
PRX Life 2, 043003 (2024)Cytoplasmic streaming, the persistent flow of fluid inside a cell, induces intracellular transport, which plays a key role in fundamental biological processes. In meiosis II mouse oocytes (developing egg cells) awaiting fertilisation, the spindle, which is the protein structure responsible for dividing genetic material in a cell, must maintain its ...
arxiv +1 more source
Stabilization of turning processes using spindle feedback with state-dependent delay [PDF]
, 2017 We develop a stabilization strategy of turning processes by means of delayed spindle control. We show that turning processes which contain intrinsic state-dependent delays can be stabilized by a spindle control with state-dependent delay, and develop analytical description of the stability region in the parameter space.
arxiv +1 more source
The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment
Stem Cell Reports, 2017 Summary: The spindle assembly checkpoint plays a pivotal role in preventing aneuploidy and transformation. Many studies demonstrate impairment of this checkpoint in cancer cells.
Andreas Brown +9 more
doaj
Improving Performance of Iterative Methods by Lossy Checkponting [PDF]
, 2018 Iterative methods are commonly used approaches to solve large, sparse linear systems, which are fundamental operations for many modern scientific simulations. When the large-scale iterative methods are running with a large number of ranks in parallel, they have to checkpoint the dynamic variables periodically in case of unavoidable fail-stop errors ...
arxiv +1 more source
PEBP1/RKIP: from multiple functions to a common role in cellular processes [PDF]
arXiv, 2018 PEBPs (PhosphatidylEthanolamine Binding Proteins) form a protein family widely present in the living world since they are encountered in microorganisms, plants and animals. In all organisms PEBPs appear to regulate important mechanisms that govern cell cycle, proliferation, differentiation and motility.
arxiv
Thymoquinone disrupts the microtubule dynamics in fission yeast Schizosaccharomyces pombe
AIMS Genetics, 2016 Mad2 deletion strain of Schizosaccharomyces pombe was found to be sensitive to thymoquinone, a signature molecule present in Nigella sativa in a dose-dependent manner.
Nusrat Masood +3 more
doaj +1 more source
arXiv, 2014 In this paper, spindle starshaped sets are introduced and investigated, which apart from normalization form an everywhere dense subfamily within the family of starshaped sets. We focus on proving spindle starshaped analogues of recent theorems of Bobylev, Breen, Toranzos, and Zamfirescu on starshaped sets.
arxiv
Optimal Multi-Level Interval-based Checkpointing for Exascale Stream Processing Systems [PDF]
arXiv, 2019 State-of-the-art stream processing platforms make use of checkpointing to support fault tolerance, where a "checkpoint tuple" flows through the topology to all operators, indicating a checkpoint and triggering a checkpoint operation. The checkpoint will enable recovering from any kind of failure, be it as localized as a process fault or as wide spread ...
arxiv