Results 11 to 20 of about 457,484 (165)

Pirfenidone: An Encouraging Therapeutic Approach For Enhancing Lateral Spinothalamic Tract Function After Spinal Cord Compression Injury [PDF]

Journal of Rawalpindi Medical College
Objective: The objective of this study was to investigate whether intraperitoneally administered pirfenidone could enhance the sensory activity of the lateral spinothalamic tract in rats after compression injury to the spinal cord.
Noman Ullah Wazir, Ambereen Humayun, Irum Javaid, Asma Amir, Nayyab Khattak, Ayesha Iftikhar   +5 more
doaj   +2 more sources

Injury of the Spinothalamic Tract Following Whiplash Injury: A Diffusion Tensor Tractography Study

Journal of Integrative Neuroscience, 2023
Objectives: Using diffusion tensor tractography (DTT), we demonstrated the spinothalamic tract (STT) injury in patients with central pain following whiplash injury.
Sung Ho Jang, Kyong Kim, You Sung Seo
doaj   +2 more sources

Sensory Function and Chronic Pain in Multiple Sclerosis

Pain Research and Management, 2018
Objective. To examine whether hypoesthesia and chronic pain are related in patients with MS. Methods. Sixty-seven MS patients with pain and 80 persons without MS were included. Sensory functioning was tested by bedside neurological examination.
Rogier J. Scherder, Neeltje Kant, Evelien T. Wolf, Bas C. M. Pijnenburg, Erik J. A. Scherder   +4 more
doaj   +2 more sources

Thermal Stimulation Changes Diffusivity of the Spinothalamic Tract. [PDF]

Spine (Phila Pa 1976), 2018
Study designAn experimental study.ObjectiveThis study aimed to investigate task-dependent changes in fractional anisotropy (FA) within the spinal cord during painful stimulation.Summary of background dataEarlier experiments by Mandl et al (2008, 2013 ...
Lin JC, Mueller C, Younger JW.
europepmc   +2 more sources

The human spinothalamic tract: lessons from cordotomy. [PDF]

Brain Commun
The spinothalamic tract has long been known as a primary conductor of nociceptive information, with its anatomical and physiological understanding evolving over centuries of research.
Allam AK, Larkin MB, Patel IA, Hasen M, Mears D, Dougherty P, Viswanathan A.   +6 more
europepmc   +2 more sources

An atypical pontine infarction presenting with segmental sensory disturbance and uncrossed sensory symptomatology: case report

Heliyon, 2020
We reported a patient who presented with analgesia and thermanaesthesia from the face to T4 dermatome on the contralateral side to the lesion due to infarction of the dorsal tegmentum of the caudal pons, which was inconsistent with classical dorsolateral
Liumin Wang, Tongchao Geng, Shucheng Gang   +2 more
doaj   +1 more source

17. Cancer Pain: Part I: Cordotomy for Unilateral Pain due to Cancer. [PDF]

Pain Pract
ABSTRACT Introduction Despite advancements in pharmacological and intrathecal treatment of oncological pain, it remains a significant challenge, affecting 44.5% of patients with cancer, with 30.6% experiencing moderate‐to‐severe pain. Methods This scoping review provides a summary of the literature from 2016 to 2024, focusing on percutaneous cordotomy ...
Huisman B, Puylaert M, Liem L, Sharma M, Ket JCF, Cohen SP, Vissers K, Steegers M.   +7 more
europepmc   +2 more sources

Cervical Cordotomy in Terminal Cancer: Pain Relieving in Oncological Treatment

Brazilian Neurosurgery, 2021
Cordotomy consists in the discontinuation of the lateral spinothalamic tract (LST) in the anterolateral quadrant of the spinal cord, which aims to reduce the transference of nociceptive information in the dorsal horn of the gray matter of the spinal cord
Maria Clara Cardoso Seba, Henrique Nicola Santo Antonio Bernardo, Natally Marques Santiago Sarturi, Thania Gonzalez Rossi, Newton Maciel de Oliveira, Paulo Henrique Pires de Aguiar   +5 more
doaj   +1 more source

Affective Touch: The Enigmatic Spinal Pathway of the C-Tactile Afferent

Neuroscience Insights, 2020
C-tactile afferents are hypothesized to form a distinct peripheral channel that encodes the affective nature of touch. Prevailing views indicate they project, as with other unmyelinated afferents, in lamina I-spinothalamic pathways that relay ...
Andrew G Marshall, Francis P McGlone
doaj   +1 more source

Changes in Diffuse Tensor Imaging and Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation in Traumatic Brain Injury with Central Pain

Brain Sciences, 2020
Post-trauma chronic pain characterized by central pain is a symptom following traumatic brain injury (TBI). Studies on the effect of repetitive transcranial magnetic stimulation (rTMS) on central pain and the association between central pain and ...
Dong-Ha Kang, Gi-Wook Kim
doaj   +1 more source