White matter microstructure predicts measures of clinical symptoms in chronic back pain patients
Chronic back pain (CBP) has extensive clinical and social implications for its sufferers and is a major source of disability. Chronic pain has previously been shown to have central neural factors underpinning it, including the loss of white matter (WM ...
Jason W. Robertson +2 more
doaj +1 more source
Global White Matter Damage in Focal Brainstem Injury Patients With Disorders of Consciousness: A Diffusion Tensor Tractography Study. [PDF]
ABSTRACT Background Disorders of consciousness (DoC) pose significant challenges in clinical diagnosis and treatment. This study aims to investigate the relationship between consciousness levels and the brainstem‐cortical white matter tracts in DoC patients resulting from focal brainstem injury using diffusion tensor imaging (DTI).
Wang M +12 more
europepmc +2 more sources
Neuronal circuitry for pain processing in the dorsal horn [PDF]
Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception.
A Dhaka +159 more
core +1 more source
Complex Regional Pain Syndrome of Non-hemiplegic Upper Limb in a Stroke Patient: A Case Report [PDF]
Complex regional pain syndrome (CRPS) type I in stroke patients is usually known to affect the hemiplegic upper limb. We report a case of CRPS presented in an ipsilesional arm of a 72-year-old female patient after an ischemic stroke at the left middle ...
Ahry Lee +3 more
doaj +1 more source
Thermosensory thalamus: parallel processing across model organisms
The thalamus acts as an interface between the periphery and the cortex, with nearly every sensory modality processing information in the thalamocortical circuit.
Tobias M. Leva +5 more
doaj +1 more source
Co-Localization of p-CREB and p-NR1 in Spinothalamic Neurons in a Chronic Muscle Pain Model [PDF]
Activation of the cAMP pathway is an important mediator of chronic muscle pain. This study examined phosphorylation of the transcription factor cAMP-response-element-binding protein (p-CREB) and the NR1 subunit of the NMDA receptor (p-NR1) in the spinal ...
Bement, Marie K. Hoeger +1 more
core +2 more sources
Excitatory postsynaptic potentials in rat neocortical neurons in vitro. III. Effects of a quinoxalinedione non-NMDA receptor antagonist [PDF]
1. Intracellular microelectrodes were used to obtain recordings from neurons in layer II/III of rat frontal cortex. A bipolar electrode positioned in layer IV of the neocortex was used to evoke postsynaptic potentials.
Hablitz, John H., Sutor, Bernd
core +1 more source
Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch [PDF]
Date of Acceptance: 08/07/2015 Acknowledgements This work was supported by grants from the Ministry of Science and Technology of China (2012CB966904, 2011CB51005), National Natural Science Foundation of China (31271182, 81200692, 91232724, 81200933 ...
Chai, Guo-Dong +11 more
core +1 more source
OPEN ANTERIOR CORDOTOMY AS A POSSIBLE TECHNIQUE FOR PAIN RELIEF IN CANCER PATIENT: AN EXPERIENCE WITH SEVEN CASES [PDF]
Seven patients who had intractable pain of the pelvis and lower extremities were scheduled for cordotomy of the spinothalamic tracts after preliminary investigations.
Sheikhrezai +4 more
doaj +1 more source
Orbitofrontal cortex mediates pain inhibition by monetary reward [PDF]
Pleasurable stimuli, including reward, inhibit pain, but the level of the neuraxis at which they do so and the cerebral processes involved are unknown. Here, we characterized a brain circuitry mediating pain inhibition by reward.
Apkarian +65 more
core +2 more sources

