Results 121 to 130 of about 61,341 (287)

Machine learning approach to identify phenotypes in patients with ischaemic heart failure with reduced ejection fraction

European Journal of Heart Failure, EarlyView.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes.
Luca Monzo, Emmanuel Bresso, Kenneth Dickstein, Bertram Pitt, John G.F. Cleland, Stefan D. Anker, Carolyn S.P. Lam, Mandeep R. Mehra, Dirk J. van Veldhuisen, Barry Greenberg, Faiez Zannad, Nicolas Girerd   +11 more
wiley   +1 more source

National survey of the prevalence, incidence, primary care burden, and treatment of heart failure in Scotland [PDF]

, 2004
Objective: To examine the epidemiology, primary care burden, and treatment of heart failure in Scotland, UK. Design: Cross sectional data from primary care practices participating in the Scottish continuous morbidity recording scheme between 1 April ...
Capewell, S., Chalmers, J., Kirkpatrick, M., MacIntyre, K., McAlister, F.A., McMurray, J., Murphy, N.F., Redpath, A., Simpson, C.R., Stewart, S.   +9 more
core   +2 more sources

Minimization or withdrawal of oral pharmacotherapy in chronic heart failure patients with improved myocardial function: A systematic review

European Journal of Heart Failure, EarlyView.
This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy.
Yuxiang Luo, Wenbin Xiao, Yusuf Z. Sener, Wouter C. Meijers, Robert M.A. van der Boon, Elfatih A. Hasabo, Osama Soliman, Rudolf A. de Boer, Kadir Caliskan   +8 more
wiley   +1 more source

Anaemia in patients with heart failure and mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
ABSTRACT Aims Anaemia is common in heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and associated with poor clinical outcomes. While renin–angiotensin system blockers reduce haemoglobin, little is known about the effect of mineralocorticoid receptor antagonists on haemoglobin and in patients with anaemia.
Misato Chimura, Mingming Yang, Alasdair D. Henderson, Pardeep S. Jhund, Kieran F. Docherty, Brian L. Claggett, Akshay S. Desai, Gerasimos Filippatos, Grzegorz Gajos, Katharina Mueller, Andrea Glasauer, Katja Rohwedder, Prabhakar Viswanathan, Carolyn S.P. Lam, Naoki Sato, Michele Senni, Adriaan A. Voors, Faiez Zannad, Mehmet B. Yilmaz, Bertram Pitt, Muthiah Vaduganathan, Scott D. Solomon, John J.V. McMurray, on behalf of the FINEARTS‐HF Committees and Investigators   +23 more
wiley   +1 more source

Benchmarking Deep Learning Architectures for Predicting Readmission to the ICU and Describing Patients-at-Risk

, 2020
Objective: To compare different deep learning architectures for predicting the risk of readmission within 30 days of discharge from the intensive care unit (ICU).
Barbieri, Sebastiano, Gallagher, Martin, Jorm, Louisa, Kemp, James, Kotwal, Sradha, Perez-Concha, Oscar, Ritchie, Angus   +6 more
core   +1 more source

Resistant hypertension? Time to consider this fourth-line drug [PDF]

, 2016
Resistant hypertension? Time to consider this fourth-line drug For most adults with resistant hypertension, spironolactone is superior to doxazosin and bisoprolol as an adjunct to triple therapy.
Kaysin, Alexander, Mounsey, Anne
core   +2 more sources

Dapagliflozin and Spironolactone Improved Clinical Symptoms and CV Outcomes in Patient with HF Preserved Ejection Fraction (HFpEF) in Hard-to-Reach Rural African Population: A Case Series

, 2022
Dominick Mkombozi Raphael, Abdu Hussein Mogella, Elias Edrick Mtalemwa, Beatrice Kabuka   +3 more
openalex   +2 more sources

Albuminuria as a diagnostic criterion and a therapeutic target in heart failure and other cardiovascular disease

European Journal of Heart Failure, EarlyView.
The value of uACR. CKD, chronic kidney disease; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; uACR, urine albumin‐to‐creatinine ratio. Abstract The high disease burden and bidirectional relationship of chronic kidney disease (CKD), heart failure (HF) and other cardiovascular disease (CVD) necessitate the need for early ...
Biykem Bozkurt, Patrick Rossignol, Joseph A. Vassalotti   +2 more
wiley   +1 more source

SPIRONOLACTONE FOR NONRESOLVING CENTRAL SEROUS CHORIORETINOPATHY: A RANDOMIZED CONTROLLED CROSSOVER STUDY. [PDF]

, 2015
PURPOSE: To evaluate the effect of spironolactone, a mineralocorticoid receptor antagonist, for nonresolving central serous chorioretinopathy. METHODS: This is a prospective, randomized, double-blinded, placebo-controlled crossover study. Sixteen eyes of
Batista, R., Behar-Cohen, F., Bergin, C., Beydoun, T., Bousquet, E., Brandely, M.L., Chast, F., Couraud, B., Farman, N., Gaudric, A., Rothschild, P.R., Zhao, M.   +11 more
core   +4 more sources

Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19 [PDF]

, 2020
Flavio Cadegiani, Carlos Gustavo Wambier, Andy Goren   +2 more
openalex   +1 more source