Recent Developments in Azomethine Ylide-Initiated Double Cycloadditions. [PDF]
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Enantioselective synthesis of spiro[indoline-3,1'-pyrazolo[1,2-<i>b</i>]phthalazine] derivatives <i>via</i> an organocatalytic three-component cascade reaction. [PDF]
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Spirocyclic compounds: potential drug leads in the fight against <i>Mycobacterium tuberculosis</i>. [PDF]
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Silica/APTPOSS anchored on MnFe2O4 as an efficient nanomagnetic composite for the preparation of spiro-pyrano [2, 3-c] chromene derivatives. [PDF]
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Fe3O4@gC3N4@Thiamine: a novel heterogeneous catalyst for the synthesis of heterocyclic compounds and microextraction of tebuconazole in food samples. [PDF]
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Nitrone chemistry: a versatile gateway to diverse heterocycles. [PDF]
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Organic & Biomolecular Chemistry, 2022Recent advances in the chemistry of base-, metal-, nano-metal and organo-catalyst mediated achiral and chiral versions of the structurally diverse and pharmaceutically relevant spirooxindoles are gently reviewed.
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Enantioselective Construction of Spirooxindole-Fused Cyclopentanes
The Journal of Organic Chemistry, 2021The present study reports an asymmetric organocatalytic cascade reaction of oxindole derivates with α,β-unsaturated aldehydes efficiently catalyzed by simple chiral secondary amine. Spirooxindole-fused cyclopentanes were produced in excellent isolated yields (up to 98%) with excellent enantiopurities (up to 99% ee) and moderate to high ...
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Recent Strategies in the Synthesis of Spiroindole and Spirooxindole Scaffolds
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