Results 141 to 150 of about 1,562 (203)

Spirocyclic compounds: potential drug leads in the fight against <i>Mycobacterium tuberculosis</i>. [PDF]

open access: yesFuture Med Chem
Kumar P   +7 more
europepmc   +1 more source

Nitrone chemistry: a versatile gateway to diverse heterocycles. [PDF]

open access: yesRSC Adv
Mohapatra S   +4 more
europepmc   +1 more source
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Expeditious entry into carbocyclic and heterocyclic spirooxindoles

Organic & Biomolecular Chemistry, 2022
Recent advances in the chemistry of base-, metal-, nano-metal and organo-catalyst mediated achiral and chiral versions of the structurally diverse and pharmaceutically relevant spirooxindoles are gently reviewed.
Madhu Ganesh, Shammy Suraj
openaire   +2 more sources

Enantioselective Construction of Spirooxindole-Fused Cyclopentanes

The Journal of Organic Chemistry, 2021
The present study reports an asymmetric organocatalytic cascade reaction of oxindole derivates with α,β-unsaturated aldehydes efficiently catalyzed by simple chiral secondary amine. Spirooxindole-fused cyclopentanes were produced in excellent isolated yields (up to 98%) with excellent enantiopurities (up to 99% ee) and moderate to high ...
Vojtěch Dočekal   +7 more
openaire   +2 more sources

A New Route to Spirooxindoles

Organic Letters, 2000
[reaction: see text]Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.
S T, Hilton   +3 more
openaire   +2 more sources

Recent Strategies in the Synthesis of Spiroindole and Spirooxindole Scaffolds

Topics in Current Chemistry, 2021
Spiroindole and spirooxindole scaffolds are very important spiro-heterocyclic compounds in drug design processes. Significant attention has been directed at obtaining molecules based on spiroindole and spirooxindole derivatives that have bioactivity against cancer cells, microbes, and different types of disease affecting the human body.
Mohammad Bayat, Shima Nasri
exaly   +3 more sources

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