Results 141 to 150 of about 1,205 (207)

Exploiting spirooxindoles for dual DNA targeting/CDK2 inhibition and simultaneous mitigation of oxidative stress towards selective NSCLC therapy; synthesis, evaluation, and molecular modelling studies. [PDF]

RSC Med Chem
Islam MS, Al-Jassas RM, Al-Majid AM, Haukka M, Nafie MS, Abu-Serie MM, Teleb M, El-Yazbi A, Alayyaf AMA, Barakat A, Shaaban MM.   +10 more
europepmc   +1 more source

Natural product-inspired [3 + 2] cycloaddition-based spirooxindoles as dual anticancer agents: synthesis, characterization, and biological evaluation by in vitro and in silico methods. [PDF]

RSC Med Chem
Nivetha N, Don Hamid J, Simha N A, Devegowda D, Ramu R, Velmathi S.   +5 more
europepmc   +1 more source

Utilizing MEDT analysis of [3 + 2] cycloaddition reaction: x-ray crystallography of spirooxindole linked with thiophene/furan heterocycles and triazole framework. [PDF]

BMC Chem
Alayyaf AA, Ali M, Alwehaibi MA, Al-Muhanna MK, Soliman SM, Ríos-Gutiérrez M, Haukka M, Barakat A.   +7 more
europepmc   +1 more source

Recent advances in microwave-assisted multicomponent synthesis of spiro heterocycles. [PDF]

RSC Adv
Javahershenas R, Makarem A, Klika KD.
europepmc   +1 more source

Recent Advances in the Enantioselective Organocatalytic [4+2] Cycloadditions. [PDF]

Molecules
Bauer T.
europepmc   +1 more source

Recent Breakthroughs in Cyclizations of <i>Ortho</i>-Quinone Methides. [PDF]

Molecules
Wang D, Guo J, Tan L, Qiu L, Reddy CVS, Xia W.   +5 more
europepmc   +1 more source

Editorial: Five-membered ring heterocyclic compounds as anticancer drug candidates. [PDF]

Front Chem
Mermer A, Orhan İE, Ye G, Kumar NA, Danac R.   +4 more
europepmc   +1 more source

Synthesis of novel spiro[chromeno[2,3-d][1,3,4]thiadiazolo[3,2-a] pyrimidines via an isatin-based three-component reaction. [PDF]

Sci Rep
Khalili M, Esmaeili AA.
europepmc   +1 more source

Promoted synthesis of spirooxindoles in the presence of chitosan containing an acidic ionic liquid bridge in aqueous medium. [PDF]

RSC Adv
Amiri M, Seyedi N, Shirini F, Tajik H.
europepmc   +1 more source

The Development of Biologically Important Spirooxindoles as New Antimicrobial Agents

Current Medicinal Chemistry, 2018
Background: Antibiotic resistance is one of the biggest threats to global health today, leading to higher medical costs and increased mortality. Because of the emergence and rapid spread of new resistance mechanisms globally, a growing number of ...
Guochao Liao, Bin Yu
exaly   +2 more sources