Results 181 to 189 of about 53,406 (189)
SF3B1 thermostability as an assay for splicing inhibitor interactions. [PDF]
J Biol ChemAmorello AN +5 more
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RNA Splicing by the Spliceosome.
Annual Review of Biochemistry, 2019The spliceosome removes introns from messenger RNA precursors (pre-mRNA). Decades of biochemistry and genetics combined with recent structural studies of the spliceosome have produced a detailed view of the mechanism of splicing.
M. E. Wilkinson, C. Charenton, K. Nagai
semanticscholar +1 more source
How Is Precursor Messenger RNA Spliced by the Spliceosome?
Annual Review of Biochemistry, 2019Splicing of the precursor messenger RNA, involving intron removal and exon ligation, is mediated by the spliceosome. Together with biochemical and genetic investigations of the past four decades, structural studies of the intact spliceosome at atomic ...
R. Wan, R. Bai, X. Zhan, Yigong Shi
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Mechanism for the initiation of spliceosome disassembly.
NatureMatthias K. Vorländer +9 more
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Mechanistic insights into precursor messenger RNA splicing by the spliceosome
Nature reviews. Molecular cell biology, 2017Yigong Shi
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Cryo-EM structure of a human spliceosome activated for step 2 of splicing
Nature, 2017K. Bertram +9 more
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Structure of a yeast activated spliceosome at 3.5 Å resolution
Science, 2016Chuangye Yan +4 more
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