Results 221 to 230 of about 58,017 (329)

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review). [PDF]

Oncol Rep
Zhu W, Wu Z, Luv C, Bao B, Zhao W, Chen G, Yang H, Ai H, Liu F, Li Z.   +9 more
europepmc   +1 more source

The Spliceosome [PDF]

Molecular Cell, 2002
openaire   +1 more source

Decision letter: Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation

, 2016

openalex   +1 more source

Identification of miRNAs Expression Characteristics and Biomarkers in Serum‐Derived Exosomes of Wilson’s Disease Patients

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Wilson’s disease (WD), caused by mutations in the ATP7B gene, leads to copper accumulation and multi‐organ damage. Exosomal microRNAs (miRNAs) play a crucial role in cell‐to‐cell communication and the pathogenesis of diseases, yet their study in WD remains unreported.
Hong Chen, Xie Wang, Ying Ma, Yue Pu, Hao Ye, Juan Zhang, Duo Zhang   +6 more
wiley   +1 more source

KAT2A-driven succinylation of SRSF11 enforces spliceosome-mediated RAD52 splicing to promote homologous recombination and radioresistance in hepatocellular carcinoma [PDF]

Jun Wu, Jingsheng Yuan, Zijian Liu, Yongjie Zhou, Bingbo Zhang, Yahong Xu, Qiwen Zeng, Zhenru Wu, Lingxiang Kong, Jinliang Wang, Bohan Zhang, Jian Yang, Tao Lv, Yujun Shi, Jiayin Yang   +14 more
openalex   +1 more source

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease

Alzheimer's & Dementia, 2019
Y. Hsieh, Caiwei Guo, H. Yalamanchili, Measho H. Abreha, Rami al-Ouran, Yarong Li, E. Dammer, J. Lah, A. Levey, D. Bennett, P. D. De Jager, N. Seyfried, Zhandong Liu, J. Shulman   +13 more
semanticscholar   +1 more source

Likely Pathogenic/Pathogenic Variants in the Spliceosome Complex Genes SNRNP200, SF3B1, SF3B2, and SF3B4 Implicated in Nonsyndromic Orofacial Cleft. [PDF]

Hum Mutat
Ranji P, Pairet E, Helaers R, Brouillard P, Bayet B, Gerdom A, Revencu N, Vikkula M.   +7 more
europepmc   +1 more source

Supplementary Table S2 from <i>RBM10</i> Loss Promotes <i>EGFR</i>-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition

Yufang Bao, Sirui Zhang, Xiaoyu Zhang, Yunjian Pan, Yueren Yan, Ning Wang, Yunpeng Ren, Ji Zuo, Wei‐Xing Zong, Zefeng Wang, Yongbo Wang   +10 more
openalex   +1 more source

RNA-Seq Reveals Spliceosome and Proteasome Genes as Most Consistent Transcripts in Human Cancer Cells

, 2013
Tara MacRae, Tobias Sargeant, Sébastien Lemieux, Josée Hébert, Éric Deneault, Guy Sauvageau   +5 more
openalex   +2 more sources

Data from Targeting the Deregulated Spliceosome Core Machinery in Cancer Cells Triggers mTOR Blockade and Autophagy

, 2023
Virginie Quidville, Samar Alsafadi, Aïcha Goubar, Frédéric Commo, Véronique Scott, Catherine Pioche‐Durieu, Isabelle Girault, Sonia Baconnais, Éric Le Cam, Vladimir Lazar, Suzette Delaloge, Mahasti Saghatchian, Patricia Pautier, Philippe Morice, Philippe Dessen, Stéphan Vagner, Fabrice André   +16 more
openalex   +1 more source