Results 91 to 100 of about 7,418 (222)

Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. [PDF]

open access: bronze, 1986
Usha Vijayraghavan   +6 more
openalex   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang   +6 more
wiley   +1 more source

YIPF2 regulates genome integrity

open access: yesCell & Bioscience
Understanding of the mechanisms for genome integrity maintenance can help in developing effective intervention strategies to combat aging. A whole-genome RNAi screen was conducted to identify novel factors involved in maintaining genome stability.
Xiao Zhang, Tao Wang
doaj   +1 more source

Comparative transcriptomic analysis revealed specific modules and hub heat-responsive genes in perennial ryegrass

open access: yesGrass Research
Perennial ryegrass (Lolium perenne) is one of the most important cool-season grasses used for forage and turf purposes. Heat stress is the primary abiotic factor threatening its pasture/turf persistence.
Wenxi Zha   +4 more
doaj   +1 more source

Phosphate Resupply Differentially Impacts the Shoot and Root Proteomes of Arabidopsis thaliana Seedlings

open access: yesPlant, Cell &Environment, Volume 49, Issue 3, Page 1598-1616, March 2026.
ABSTRACT Phosphate (Pi) is an essential macronutrient for plant development that is often limited in soil. Plants have evolved dynamic biochemical, physiological and morphological adaptations to cope with Pi deficiency, known as the Pi starvation response (PSR).
Milena A. Smith   +5 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, Volume 16, Issue 2, Page 299-313, February 2026.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Integrating Phylogenetics With Intron Positions Illuminates the Origin of the Complex Spliceosome [PDF]

open access: gold, 2023
Julian Vosseberg   +3 more
openalex   +1 more source

A Novel N‐Terminal PRPF6 Variant in Autosomal Dominant Retinitis Pigmentosa

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT This report identifies the first N‐terminal PRPF6 variant (c.514C>T) as a cause of autosomal dominant Retinitis Pigmentosa. This novel variant is associated with progressive peripheral vision loss but notably preserved central visual acuity, suggesting a distinct phenotypic expression compared to C‐terminal variants.
Na Li, Yalong Dang
wiley   +1 more source

Real‐world experience with CPX‐351 for secondary acute myeloid leukaemia: Comparison with FLAG‐IDA in a propensity score matching analysis

open access: yes
British Journal of Haematology, EarlyView.
Maria Agustina Perusini   +19 more
wiley   +1 more source

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