Results 111 to 120 of about 6,327 (242)

YIPF2 regulates genome integrity

Cell & Bioscience
Understanding of the mechanisms for genome integrity maintenance can help in developing effective intervention strategies to combat aging. A whole-genome RNAi screen was conducted to identify novel factors involved in maintaining genome stability.
Xiao Zhang, Tao Wang
doaj   +1 more source

Comparative transcriptomic analysis revealed specific modules and hub heat-responsive genes in perennial ryegrass

Grass Research
Perennial ryegrass (Lolium perenne) is one of the most important cool-season grasses used for forage and turf purposes. Heat stress is the primary abiotic factor threatening its pasture/turf persistence.
Wenxi Zha, Lingshuang Zeng, Ziyi Zhang, Jing Zhang, Bin Xu   +4 more
doaj   +1 more source

Pentatricopeptide repeat proteins in crops: Advances in functional mechanisms and breeding applications

Journal of Integrative Plant Biology, EarlyView.
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu, Maohong Cai, Rongrong Zhai, Jing Ye, Guofu Zhu, Faming Yu, Shenghai Ye, Xiaoming Zhang   +7 more
wiley   +1 more source

Two spliceosomes can form simultaneously and independently on synthetic double-intron messenger RNA precursors

, 1987
We have investigated the formation of splicing complexes in vitro on mRNA precursors (pre-mRNAs) containing two introns. Sucrose gradient sedimentation analysis revealed that the double-intron substrate becomes associated with 60S structures, which are ...
Christofori, G., Frendewey, D., Keller, W.   +2 more
core  

The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome

, 2009
Metazoan spliceosomes exhibit an elaborate protein composition required for canonical and alternative splicing. Thus, the minimal set of proteins essential for activation and catalysis remains elusive.
Fabrizio, Patrizia, Dube, P., Stark, H., Dannenberg, Julia, Urlaub, Henning, Stark, Holger, Dannenberg, J., Urlaub, H., Dube, Prakash, Fabrizio, P., Kastner, B., Kastner, Berthold, Lührmann, R., Lührmann, Reinhard   +13 more
core   +1 more source

Pangenome analysis reveals the genetic mechanism underlying high‐altitude adaptation in Qinghai–Xizang (Tibet) Plateau Rhododendron

Journal of Integrative Plant Biology, EarlyView.
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou, Zhongping Xu, Fanhuang Zeng, Haiyu Sang, Zhenhua Liu, Miao Sun, Qiang Fu, Kaige Zhao, Daming Tan, Manzhu Bao, Shuangxia Jin, Xiuqun Liu   +11 more
wiley   +1 more source

Optimized TadA‐derived base editors efficiently manipulate mRNA splicing by A‐to‐G and C‐to‐K editing in potato

Journal of Integrative Plant Biology, EarlyView.
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen, Yan Zhang, Jiuzhou Deng, Lumin Zhang, Huiying Zhou, Yaxin Duan, Enle Xiao, Guangtao Zhu, Chunzhi Zhang   +8 more
wiley   +1 more source

Localisation of Neuregulin 1-?3 to different sub-nuclear structures alters gene expression

, 2011
Neuregulins are growth factors that signal via the ErbB3 and ErbB4 receptors. Here we show using immunohistochemistry that they are often expressed in the nucleus of a range of tumour types including soft tissue and breast.
Ming Wang, William J. Gullick, Carol M. Trim, Gullick, William J., Trim, Carol M., Wang, Ming   +5 more
core   +1 more source

Evaluating the Combined Effects of Elevated [CO2] and Accelerated NPQ Relaxation on Yield, Physiology and Transcription in Soybean

Plant, Cell &Environment, EarlyView.
ABSTRACT Improving photosynthesis is proposed as a means of enhancing crop productivity. To assess whether simultaneous increases in light use‐efficiency and carbon assimilation are additive, we investigated the impact of elevated CO2 on the performance of a transgenic soybean line engineered for faster relaxation of photoprotection by overexpression ...
Dilkaran Singh, Amanda P. De Souza, Lynn Doran, Atinder Singh, Jeffrey Hansen, Laurie Beth Leonelli, Steven J. Burgess   +6 more
wiley   +1 more source

Effect of RNase A and transcriptional inhibition on the intranuclear distribution of MUC1.

, 2013
(A) BeWo cells were fixed and permeabilized using methanol and then incubated with RNase A (100 µg/mL) for 2 h as described in Methods. The cells were then stained with antibodies against MUC1 (HMFG1 and B27.29), U2AF65, and spliceosomes as indicated ...
Priyadarsina Kumar (312156), Gordon C. Douglas (312163), Louise Lindberg (312157), Twanda L. Thirkill (312158), Jennifer W. Ji (312159), Lindsay Martsching (312161)   +5 more
core   +1 more source