Results 121 to 130 of about 6,735 (249)
Animal Genetics, Volume 57, Issue 5, October 2026.ABSTRACT Environmental stressors in commercial poultry systems can negatively affect bird welfare, although individuals vary considerably in their responses. Neuroplasticity within the hippocampus, measured through the density of doublecortin‐positive (DCX+) neurons, provides a potential biomarker of stress experience in laying hens.
Lindsay Neuert +8 more
wiley +1 more source
Localisation of Neuregulin 1-?3 to different sub-nuclear structures alters gene expression
, 2011 Neuregulins are growth factors that signal via the ErbB3 and ErbB4 receptors. Here we show using immunohistochemistry that they are often expressed in the nucleus of a range of tumour types including soft tissue and breast.
Ming Wang +5 more
core +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo +3 more
wiley +1 more source
Quantitation of Cirtuvivint (SM08502) in Human Plasma by LC–MS/MS
Biomedical Chromatography, Volume 40, Issue 10, October 2026.ABSTRACT CDC‐like kinases (CLK) and dual‐specificity tyrosine‐regulated kinases (DYRK) are protein kinases involved in various cellular functions, mRNA splicing, and DNA damage repair. CLK/DYRK kinases have been implicated in many disorders such as diabetes, neurodegenerative diseases, and cancer.
Julianne L. Holleran +10 more
wiley +1 more source
Relating transcriptomics to protein abundance reveals self‐driven versus interactor‐driven proteins
Protein Science, Volume 35, Issue 10, October 2026.Abstract Statistically modeling the interdependence between transcriptomics and protein abundances remains a persistent challenge in bioinformatics research. Transcriptomic data and proteomic abundances typically display a moderate Pearson's correlation of about 0.5, while in tumor conditions, the correlation may decrease to a much weaker correlation ...
Loulwah Arnaout +2 more
wiley +1 more source
The EMBO JournalThe B complex is a key intermediate stage of spliceosome assembly. To improve the structural resolution of monomeric, human spliceosomal B (hB) complexes and thereby generate a more comprehensive hB molecular model, we determined the cryo-EM structure of
Zhenwei Zhang +6 more
doaj +1 more source
Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 961-971, October 2026.ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du +4 more
wiley +1 more source
Clinical management of clonal hematopoiesis
Cancer, Volume 132, Issue 18, 15 September 2026.ABSTRACT Clonal hematopoiesis, particularly clonal hematopoiesis of indeterminate potential and clonal cytopenia of undetermined significance, is an age‐related premalignant condition characterized by the expansion of hematopoietic clones carrying somatic mutations.
Kelly S. Chien +1 more
wiley +1 more source
Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression
, 2011 Neuregulins are growth factors that signal via the ErbB3 and ErbB4 receptors. Here we show using immunohistochemistry that they are often expressed in the nucleus of a range of tumour types including soft tissue and breast.
Trim, C., Gullick, W., Wang, M.
core +1 more source