Results 141 to 150 of about 6,327 (242)

Sketching microprotein portraits

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The illustrations of intricate molecular machineries inside cells created by David Goodsell continue to inspire the scientific community. Here, we aim to extend his artworks to include microproteins, a newly recognized class of small proteins with less than 100 amino acids, encoded by small open reading frames.
Gabriel Diaz, Philippe Valenti, Marc Gueroult, Simon Marques‐Prieto, Kenza Benachenhou, Jennifer Zanet, Matthieu Chavent   +6 more
wiley   +1 more source

Spliceosome [PDF]

Science-Business eXchange, 2009
openaire   +2 more sources

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto, Lucia Buccarello, Giuseppe Carota, Rocco Salvatore Calabrò, Carmela Rifici, Emanuela Esposito, Alessio Ardizzone, Giuseppe Caruso   +7 more
wiley   +1 more source

Update on Nuclear Speckles in Plants Localization and Dynamics of Nuclear Speckles in Plants 1

, 2020
The generation of mature mRNAs from most genes (about 80%-90%) in autotrophic eukaryotes requires the removal of noncoding sequences (introns) and splicing of the coding regions (exons; SPLICING REGULATORS pre-mRNAs splicing takes place ...

core  

Genome‐wide association study reveals the genetic architecture of drought tolerance in maize using yield‐based resistance indices and transcriptomic evidence

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Drought is a major environmental factor limiting maize (Zea mays L.) production worldwide. Unraveling the genetic basis of drought tolerance and pinpointing key loci and candidate genes are fundamental to the molecular breeding of maize with enhanced drought resistance.
Haoyang Li, Xurong Hu, Pengyan Zhang, Yueying Zhao, Yinglu Song, Zheng Zhang, Huahu Bu, Jianzhong Chang   +7 more
wiley   +1 more source

A Bayesian‐Based Integrative Bioinformatics Analysis Nominates Oncogenic Drivers in Neuroblastoma

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Identifying targetable oncogenic drivers remains a challenge in neuroblastoma, the most common extracranial solid malignancy in children. We applied a Bayesian algorithm for integrative analysis of expression and copy‐number, iExCN, to nominate oncogenic drivers in neuroblastoma.
Lin Xu, Arhanti Sadanand, Evan W. Neczypor, Yen‐Ting Liu, Erin Butler, Kelley Moore, Flannery Bowman, Yamin Mazumder, Arlene Naranjo, Alexandre Chlenski, Xue Xiao, Lei Guo, Susan L. Cohn, Mark A. Applebaum, Stephen X. Skapek   +14 more
wiley   +1 more source

Phosphate starvation induces root cell‐type‐specific transcriptional responses and alternative splicing

New Phytologist, Volume 250, Issue 5, Page 3212-3229, June 2026.
Summary Phosphate (Pi) is an essential nutrient for plant growth, and understanding how Arabidopsis thaliana root cells respond to Pi deficiency is crucial to decipher whole plant responses. We perform high‐resolution transcriptomic profiling across five distinct root cell types, identifying differentially expressed genes (DEGs) and differential ...
Mary‐Paz González‐García, Mónica Lanza, Victoria Baca‐González, Estefano Bustillo‐Avendaño, Laura Serrano‐Ron, Sara González‐Bodi, Jose M. García‐Mina, Ángel M. Zamarreño, María Garnica, Miguel A. Moreno‐Risueno, Elena Caro, Juan C. del Pozo   +11 more
wiley   +1 more source

Comprehensive analysis of the critical transcript function of the <i>DAZAP2</i> gene in porcine testis. [PDF]

Arch Anim Breed
Zhang X, Huo H, Li H, Zhai L, Huo J.
europepmc   +1 more source

Multiple splicing factors are released from endogenous complexes during in vitro pre-mRNA splicing

, 1989
Pre-mRNA splicing occurs in a macromolecular complex called the spliceosome. Efforts to isolate spliceosomes from in vitro splicing reactions have been hampered by the presence of endogenous complexes that copurify with de novo spliceosomes formed on ...
Conway, G. C., Spector, D. L., Krainer, A. R., Roberts, R. J.   +3 more
core  

Loss of U11/U12 spliceosome gene <i>ZCRB1</i> leads to aberrant ciliogenesis and WNT signaling. [PDF]

Life Sci Alliance
Pirzada MUR, Powell-Rodgers G, Richee J, Norppa AJ, Jungers CF, Colijn S, Frilander MJ, Stratman AN, Djuranovic S.   +8 more
europepmc   +1 more source