Results 31 to 40 of about 325,490 (342)

Numerical study of the behaviour of loop bar splicing in joints of reinforced concrete structures

open access: yesRevista IBRACON de Estruturas e Materiais, 2019
Sometimes straight bar splicing takes up too much space in a reinforced concrete structure due to the required overlapping length. Therefore, in limited space situations, loop joints may be a good solution, which has been spread in civil construction ...
T. D. L.VASCONCELOS, V. G. HAACH
doaj   +2 more sources

Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome

open access: yesKidney Research and Clinical Practice, 2020
Alport syndrome (AS) is a progressive inherited kidney disease characterized by hearing loss and ocular abnormalities. There are three forms of AS depending on inheritance mode: X-linked Alport syndrome (XLAS), autosomal recessive AS (ARAS), and ...
Kandai Nozu   +10 more
doaj   +1 more source

Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60

open access: yeseLife, 2020
Splicing is a vital cellular process that modulates important aspects of animal physiology, yet roles in regulating innate immunity are relatively unexplored. From genetic screens in C.
Chun Kew   +5 more
doaj   +1 more source

The pathobiology of splicing [PDF]

open access: yesThe Journal of Pathology, 2009
AbstractNinety‐four percent of human genes are discontinuous, such that segments expressed as mRNA are contained within exons and separated by intervening segments, called introns. Following transcription, genes are expressed as precursor mRNAs (pre‐mRNAs), which are spliced co‐transcriptionally, and the flanking exons are joined together to form a ...
Amanda J. Ward, Thomas A. Cooper
openaire   +3 more sources

The paternal genome and the health of the assisted reproductive technology child

open access: yesAsian Journal of Andrology, 2015
As a number of children born by assisted reproductive technology (ART) are increasing each year across the developed world, the health of such offspring is a matter of public concern.
Sheena EM Lewis, Kishlay Kumar
doaj   +1 more source

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. [PDF]

open access: yesGenes & Development, 1988
Based on ultrastructural analysis of actively transcribing genes seen in electron micrographs, we present evidence that pre-mRNA splicing occurs with a reasonable frequency on the nascent transcripts of early Drosophila embryo genes and that splice site selection may generally precede polyadenylation.
Yvonne N. Osheim, Ann L. Beyer
openaire   +2 more sources

Inteins: Localized Distribution, Gene Regulation, and Protein Engineering for Biological Applications

open access: yesMicroorganisms, 2018
Inteins are self-splicing polypeptides with an ability to excise themselves from flanking host protein regions with remarkable precision; in the process, they ligate flanked host protein fragments.
Theetha L. Pavankumar
doaj   +1 more source

An operad for splicing [PDF]

open access: yesJournal of Topology, 2012
34 pages, 16 diagrams. V3->V4: Explicit definition of sigma^* \wr G-operads given, and proof included splicing operad is such. Re-wrote proof of Theorem 5.13 to make the equivariance of the maps more explicit. Cut down on extraneous notation.
openaire   +3 more sources

Detection of Spliced mRNA from Human Bocavirus 1 in Clinical Samples from Children with Respiratory Tract Infections

open access: yesEmerging Infectious Diseases, 2013
Human bocavirus 1 (HBoV1) is a parvovirus associated with respiratory tract infections (RTIs) in children, but a causal relation has not yet been confirmed.
Andreas Christensen   +5 more
doaj   +1 more source

Clinical and genetic analysis of classical Ehlers‐Danlos syndrome patient caused by synonymous mutation in COL5A2

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Classical Ehlers‐Danlos syndrome (cEDS) is a heterogeneous connective tissue disorder that mainly results from the germline mutation of COL5A1 and COL5A2.
Na Ma   +10 more
doaj   +1 more source

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