Results 41 to 50 of about 603,390 (338)
GHR gene transcript heterogeneity may explain phenotypic variability in GHR pseudoexon (6Ψ) patients
Endocrine Connections, 2020 Objectives: The homozygous GH receptor (GHR) pseudoexon (6Ψ) mutation leads to growth hormone insensitivity (GHI) with clinical and biochemical heterogeneity.
Sumana Chatterjee +8 more
doaj +1 more source
RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]
, 2011 Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L +2 more
core +3 more sources
The Annals of Probability, 1983 Let X be a non-empty set, \({\mathcal A}\), \({\mathcal B}\) two \(\sigma\) -algebras on X, \({\mathcal C}_ 0\) the algebra generated by their union, \({\mathcal A}\bigvee {\mathcal B}\) the \(\sigma\) -algebra generated by \({\mathcal C}_ 0\); \(\mu\), \(\nu\) probability measures on \({\mathcal A}\), \({\mathcal B}\), respectively.
Kallianpur, G., Ramachandran, D.
openaire +2 more sources
Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. [PDF]
Genes & Development, 1988 Based on ultrastructural analysis of actively transcribing genes seen in electron micrographs, we present evidence that pre-mRNA splicing occurs with a reasonable frequency on the nascent transcripts of early Drosophila embryo genes and that splice site selection may generally precede polyadenylation.
Yvonne N. Osheim, Ann L. Beyer
openaire +2 more sources
Biobanking efforts and new advances in male fertility preservation for rare and endangered species
Asian Journal of Andrology, 2015 Understanding and sustaining biodiversity is a multi-disciplinary science that benefits highly from the creation of organized and accessible collections of biomaterials (Genome Resource Banks).
Pierre Comizzoli
doaj +1 more source
Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries [PDF]
, 1993 The nuclear topography of splicing snRNPs, mRNA transcripts and chromosome domains in various mammalian cell types are described. The visualization of splicing snRNPs, defined by the Sm antigen, and coiled bodies, revealed distinctly different ...
A Monneron +64 more
core +1 more source
Biotechnology & Biotechnological Equipment, 2016 Cloning of coding sequence (CDS) is an important step for gene function research. Here, we reported a simple and efficient strategy for assembling multiple-exon into an intron-free CDS from genomic DNA (gDNA) by an isothermal recombination reaction-based
Wenxuan Chen +7 more
doaj +1 more source
eLife, 2016 Although it is currently understood that the exon junction complex (EJC) is recruited on spliced mRNA by a specific interaction between its central protein, eIF4AIII, and splicing factor CWC22, we found that eIF4AIII and the other EJC core proteins Y14 ...
Subhendu Roy Choudhury +7 more
doaj +1 more source
Cells, 2021 The essential components of splicing are the splicing factors accumulated in nuclear speckles; thus, we studied how DNA damaging agents and A-type lamin depletion affect the properties of these regions, positive on the SC-35 protein.
Soňa Legartová +5 more
doaj +1 more source
The Alternative Choice of Constitutive Exons throughout Evolution [PDF]
, 2007 Alternative cassette exons are known to originate from two processes exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution.
Adi Doron-Faigenboim +9 more
core +5 more sources