Results 41 to 50 of about 483,589 (358)
Molecular Cell, 2007 A novel study in a recent issue of Molecular Cell (Shi and Manley, 2007) provides insight into a complex signaling pathway that controls the phosphorylation status of an SR-related protein that functions as a splicing repressor following heat shock-dependent dephosphorylation.
Guil, Sonia, Cáceres, Javier F.
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The paternal genome and the health of the assisted reproductive technology child
Asian Journal of Andrology, 2015 As a number of children born by assisted reproductive technology (ART) are increasing each year across the developed world, the health of such offspring is a matter of public concern.
Sheena EM Lewis, Kishlay Kumar
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The pathobiology of splicing [PDF]
The Journal of Pathology, 2009 AbstractNinety‐four percent of human genes are discontinuous, such that segments expressed as mRNA are contained within exons and separated by intervening segments, called introns. Following transcription, genes are expressed as precursor mRNAs (pre‐mRNAs), which are spliced co‐transcriptionally, and the flanking exons are joined together to form a ...
Amanda J. Ward, Thomas A. Cooper
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Microorganisms, 2018 Inteins are self-splicing polypeptides with an ability to excise themselves from flanking host protein regions with remarkable precision; in the process, they ligate flanked host protein fragments.
Theetha L. Pavankumar
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The Annals of Probability, 1983 Let X be a non-empty set, \({\mathcal A}\), \({\mathcal B}\) two \(\sigma\) -algebras on X, \({\mathcal C}_ 0\) the algebra generated by their union, \({\mathcal A}\bigvee {\mathcal B}\) the \(\sigma\) -algebra generated by \({\mathcal C}_ 0\); \(\mu\), \(\nu\) probability measures on \({\mathcal A}\), \({\mathcal B}\), respectively.
Kallianpur, G., Ramachandran, D.
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Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. [PDF]
Genes & Development, 1988 Based on ultrastructural analysis of actively transcribing genes seen in electron micrographs, we present evidence that pre-mRNA splicing occurs with a reasonable frequency on the nascent transcripts of early Drosophila embryo genes and that splice site selection may generally precede polyadenylation.
Yvonne N. Osheim, Ann L. Beyer
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Splicing mutations in human genetic disorders: examples, detection, and confirmation
Journal of Applied Genetics, 2018 Precise pre-mRNA splicing, essential for appropriate protein translation, depends on the presence of consensus “cis” sequences that define exon-intron boundaries and regulatory sequences recognized by splicing machinery.
Abramowicz Anna, Gos Monika
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Emerging Infectious Diseases, 2013 Human bocavirus 1 (HBoV1) is a parvovirus associated with respiratory tract infections (RTIs) in children, but a causal relation has not yet been confirmed.
Andreas Christensen +5 more
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Molecular Genetics & Genomic Medicine, 2021 Background Classical Ehlers‐Danlos syndrome (cEDS) is a heterogeneous connective tissue disorder that mainly results from the germline mutation of COL5A1 and COL5A2.
Na Ma +10 more
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Frontiers in Molecular Biosciences, 2021 An evolutionarily conserved feature of introns is their ability to enhance expression of genes that harbor them. Introns have been shown to regulate gene expression at the transcription and post-transcription level.
Katherine Dwyer +3 more
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