Results 31 to 40 of about 366,865 (319)
Journal of Developmental Biology, 2023 The sexual fate of honeybees is determined by the complementary sex determination (CSD) model: heterozygosity at a single locus (the CSD locus) determines femaleness, while hemizygosity or homozygosity at the CSD locus determines maleness.
Yukihiro Suzuki +2 more
doaj +1 more source
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements [PDF]
, 2010 Background: polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evidence of aberrant splicing causing Mendelian diseases, the implication of ...
Churbanov, Alexander +8 more
core +1 more source
Diagnostics, 2022 Myelodysplastic syndromes (MDS) are considered to be diseases associated with splicing defects. A large number of genes involved in the pre-messenger RNA splicing process are mutated in MDS.
Nathalie Douet-Guilbert +3 more
doaj +1 more source
Splicing and alternative splicing in rice and humans
BMB Reports, 2013 Rice is a monocot gramineous crop, and one of the most important staple foods. Rice is considered a model species for most gramineous crops. Extensive research on rice has provided critical guidance for other crops, such as maize and wheat. In recent years, climate change and exacerbated soil degradation have resulted in a variety of abiotic stresses ...
Zhiguo E, Lei Wang, Jianhua Zhou
openaire +4 more sources
Identifying differential exon splicing using linear models and correlation coefficients [PDF]
, 2009 Background: With the availability of the Affymetrix exon arrays a number of tools have been developed to enable the analysis. These however can be expensive or have several pre-installation requirements.
Pallas Jacqueline A +7 more
core +1 more source
Splicing-associated epitopes identified using ≤300nM.
, 2021 (A) Distribution of the number of candidate tumor-specific splicing-derived neoepitopes (splicing-epitopes) and splicing-affected self-epitopes that would be depleted in the altered isoform (self-epitopes) using ≤300nM to define candidate epitopes.
Judith Pérez-Granado (11442479) +6 more
core +1 more source
Biotechnology & Biotechnological Equipment, 2016 Cloning of coding sequence (CDS) is an important step for gene function research. Here, we reported a simple and efficient strategy for assembling multiple-exon into an intron-free CDS from genomic DNA (gDNA) by an isothermal recombination reaction-based
Wenxuan Chen +7 more
doaj +1 more source
Exon definitive regions for MPC1 microexon splicing and its usage for splicing modulation
Molecular Therapy: Nucleic Acids, 2023 Alternative splicing of microexons (3–30 base pairs [bp]) is involved in important biological processes in brain development and human cancers. However, understanding a splicing process of non-3x bp microexons is scarce.
Eunjin Koh, Daye Shin, Kyung-Sup Kim
doaj +1 more source
Сахарный диабет, 2019 An erratum on «A synonymous variant in GCK gene as a cause of gestational diabetes mellitus» by Natalya A. Zubkova, Petr M. Rubtsov, Liudmila I. Ibragimova, Nina A. Makretskaya, Evgeny V. Vasiliev, Vasily M. Petrov, Anatoly N. Tiulpakov (2019)
Natalia A. Zubkova +7 more
doaj +1 more source
Cells, 2021 The essential components of splicing are the splicing factors accumulated in nuclear speckles; thus, we studied how DNA damaging agents and A-type lamin depletion affect the properties of these regions, positive on the SC-35 protein.
Soňa Legartová +5 more
doaj +1 more source