Results 71 to 80 of about 208,874 (142)

Role Of SRSF3 In Aging Periodontal Ligament Stem Cells

open access: yesInternational Dental Journal
Aim or purpose: Alternative RNA splicing generates multiple mRNA isoforms by combining different splice sites, encoding proteins with diverse functions and expanding protein expression diversity. Aging in periodontal tissues impairs their basic functions,
Liu Miaomiao, Zhu Jiaye
doaj   +1 more source

Alternative Splicing: Emerging Roles in Anti-Aging Strategies

open access: yesBiomolecules
Alternative splicing plays a fundamental role in gene expression and protein complexity. Aberrant splicing impairs cell homeostasis and is closely associated with aging and cellular senescence.
Lingyue Gao, Rong Jia
doaj   +1 more source

De novo variants in the splicing factor gene SF3B1 are associated with neurodevelopmental disorders. [PDF]

open access: yesNat Commun
Uguen K   +66 more
europepmc   +1 more source

Splicing factor FUS facilitates the progression of PIT1-lineage PitNETs by upregulating MDM2. [PDF]

open access: yesTheranostics
Wang X   +12 more
europepmc   +1 more source

The splicing factor PTBP1 interacts with RUNX1 and is required for leukemia cell survival. [PDF]

open access: yesLeukemia
Dhir A   +12 more
europepmc   +1 more source

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