Results 151 to 160 of about 7,687,875 (261)

Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review). [PDF]

Mol Med Rep
Nyalambisa A, Basera A, Xelwa N, Fadebi O, Dlamini Z, Marima R.   +5 more
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

The FUS(s) about splicing

, 2014
Fused in sarcoma (FUS), also called translocated in liposarcoma (TLS), is a ubiquitously expressed DNA/RNA binding protein belonging to the TET family and predominantly localized in the nucleus.
Ruepp, Marc-David
core  

Acidosis promotes exon skipping through sequestering SR-rich splicing factors in nuclear speckles. [PDF]

Front Mol Biosci
Shtork AS, Rubtsov PV, Kazakova AN, Pavlova II, Ivanova OM, Illarionova SE, Bogomiakova ME, Sizova SV, Proshkina GM, Strokach AA, Klimina KM, Shender VO, Deyev SM, Arapidi GP, Varizhuk AM.   +14 more
europepmc   +1 more source

The Role of Splicing Factors in Adipogenesis and Thermogenesis. [PDF]

Mol Cells, 2023
Naing YT, Sun L.
europepmc   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Herpesvirus-encoded lncRNA targets host splicing by interacting with splicing factors. [PDF]

PLoS Pathog
Hong Y, Shekhar R, McMahon S, Keil N, Baddoo M, Watkins JM, Keshishian H, Stanclift C, Carr SA, Munschauer M, Burke JM, Flemington EK, Renne R.   +12 more
europepmc   +1 more source

Bamboo‐Slip‐Inspired Conformal Reconfigurable Metasurfaces

Advanced Science, EarlyView.
Bamboo‐slip‐inspired conformal reconfigurable metasurface system. The structure is mainly composed of three parts, which are conformal metasurface, pattern reconfigurable antenna, and control components (such as Field Programmable Gate Array (FPGA)). Conformal metasurfaces draw inspiration from the design of ancient Chinese bamboo slips.
Qifan Li, Shaofeng Zhang, Qiang Feng, Dexiao Xia, Yajie Mu, Xiangjin Ma, Jiaqi Han, Haixia Liu, Guangyao Liu, Long Li   +9 more
wiley   +1 more source

Cytoplasmic RBM20 granules modulate non-RBM20 target splicing through interactions with other splicing factors. [PDF]

Nucleic Acids Res
Zhang Y, Gregorich ZR, Liu C, Larson EJ, Ge Y, Guo W.   +5 more
europepmc   +1 more source