Results 51 to 60 of about 74,782 (138)

Clinical practice guidelines for the diagnosis and treatment of osteoporosis secondary to ankylosing spondylitis

Rheumatology &Autoimmunity, EarlyView.
Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the axial skeleton and is often associated with secondary osteoporosis. Currently, there are no established international consensus or guidelines for managing AS‐related osteoporosis (AS‐OP). This guideline was jointly developed by several Chinese academic institutions,
Yasong Li, Liang Wang, Hongzhi Wang, Han Wang, Huaxiang Wu, Qifeng Ying, Dongbao Zhao, Lan He, Xuewu Zhang, Jian Zhu, Sanzhong Xu, Yi Yuan, Dun Hong, Peijian Tong, Ping Huang, Zhenchun Zhang, Hongwei Du, Yizhong Li, Xiaochun Zhu, Lijuan Wang, Zhangxuan Shou, Hao Zhang, Feng Huang, Weidong Xu   +23 more
wiley   +1 more source

Seronegative spondyloarthropathies : a review : part I: classification and differential diagnosis [PDF]

, 1993
The seronegative spondyloarthropathies comprise a group of non-rheumatoid disorders with similar clinical, laboratory and genetic features. Recognition of new clinical features has supported the notion that they all form part of a clinical spectrum ...
Borg, Andrew A., Dawes, Peter T., Hothersall, T.E.   +2 more
core  

Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn's disease [PDF]

, 2004
Background: Sacroiliitis is a common extraintestinal manifestation of Crohn's disease but its association with the HLA-B27 phenotype is less evident. Polymorphisms in the CARD15 gene have been linked to higher susceptibility for Crohn's disease.
Coucke, Paul, Cuvelier, Claude, De Keyser, Filip, De Vos, Martine, Laukens, Debby, MARICHAL, DENIS, Mielants, Herman, Peeters, Harald, Remaut, Erik, VAN DEN BERGHE, MARTINA, Vander Cruyssen, Bert   +10 more
core   +2 more sources

Impact of fibromyalgia on patient acceptable symptom state in Thai patients with spondyloarthritis: A cross‐sectional study

Rheumatology &Autoimmunity, EarlyView.
This cross‐sectional study enrolled Thai patients with spondyloarthritis to assess the prevalence and its impact. Fibromyalgia was present in 5.5% and significantly impaired health‐related quality of life and symptom perception. Low disease activity, good sleep quality, and FS < 3 were independently associated with achieving PASS.
Sittikorn Srivorrapattararkul, Praveena Chiowchanwisawakit   +1 more
wiley   +1 more source

Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis, Sandra Philipp, Thomas Mosch, Björn Fritz, Robert Sabat   +4 more
wiley   +1 more source

Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study [PDF]

, 2013
Objectives: To assess long-term golimumab efficacy/safety in patients with active psoriatic arthritis (PsA).<p></p> Methods Adult PsA patients (≥3 swollen, ≥3 tender joints, active psoriasis) were randomly assigned to ...
Beutler, A., Gladman, D.D., Kavanaugh, A., Krueger, G.G., Mack, M., McInnes, I.B., Mease, P.J., Mudivarthy, S., van der Heijde, D., Xu, W., Xu, Z.   +10 more
core   +1 more source

Evaluating Large Language Model Adherence to Targeted Fifth‐Grade Readability Standards in Patient Education on Chronic Conditions

Chronic Diseases and Translational Medicine, EarlyView.
Faheed Shafau, Chase Wahl, Marcus Kado, Garrett Miedema   +3 more
wiley   +1 more source

Exonic Variation in HLA‐C, CFB, and TAP2 Associated With Increased Risk for Comorbid Crohn's Disease and Psoriasis

International Journal of Dermatology, EarlyView.
Our recent work established an association between high polygenic risk scores (PRSes) for both psoriasis and Crohn's disease with the development of comorbid disease. The protein‐coding genetic variation associated with the development of comorbid psoriasis and Crohn's disease is understudied.
Vikram R. Shaw, Jinyoung Byun, Catherine Zhu, Jared Sninsky, Younghun Han, Jeffrey M. Cohen, Christopher I. Amos   +6 more
wiley   +1 more source

Spondyloarthritis: Matrix Metalloproteinasesas Biomarkers of Pathogenesis and Response to Tumor Necrosis Factor (TNF) Inhibitors [PDF]

, 2017
The term spondyloarthritis (SpA) is used to describe a group of multifactorial chronic inflammatory diseases characterized by a predisposing genetic background and clinical manifestations typically involving the sacroiliac joint.
Ada Aita, Breban, Daniela Basso, Giovannini, Leonardo Punzi, Maksymowych, Mario Plebani, Massova, Parma, Roberta Ramonda, Stefania Moz, Woo   +11 more
core   +1 more source

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes

International Journal of Immunogenetics, EarlyView.
ABSTRACT The etiology of ankylosing spondylitis (AS) is complex and not yet fully understood. Interleukin‐6 (IL‐6), vitamin D and the vitamin D receptor (VDR) play an important role in modulating immune response, and Torque teno virus is considered a marker of immune status. This case–control study aimed to investigate the predisposition to AS. A total
Dănuț Cimponeriu, Lavinia‐Mariana Berca, Irina Radu, Mihai Toma, Remus Nica, Silvia Nica, Roxana Măciucă   +6 more
wiley   +1 more source