Results 11 to 20 of about 54,113 (242)

Toxicity study of SARS-CoV-2 Spike protein expressed on Bacillus subtilis spores [PDF]

BMC Microbiology
Background The SARS-CoV-2 spike protein is the primary antigen used in most COVID-19 vaccines. To improve protection, especially at mucosal surfaces, a robust and safe delivery system capable of inducing both systemic and mucosal immunity is needed ...
Atiqah Hazan, Amalia A. Saperi, Nurfatihah Zulkifli, Nor-Aziyah Mat Rahim, Vunjia Tiong, Hai Yen Lee, Sazaly AbuBakar   +6 more
doaj   +2 more sources

Emerging Applications of Bacterial Spores in Nanobiotechnology [PDF]

Journal of Nanobiotechnology, 2003
Bacterial spores are robust and dormant life forms with formidable resistance properties, in part, attributable to the multiple layers of protein that encase the spore in a protective and flexible shield.
Cutting Simon M, Ricca Ezio
doaj   +5 more sources

Memory of Germinant Stimuli in Bacterial Spores [PDF]

mBio, 2015
Bacterial spores, despite being metabolically dormant, possess the remarkable capacity to detect nutrients and other molecules in their environment through a biochemical sensory apparatus that can trigger spore germination, allowing the return to ...
Shiwei Wang, James R. Faeder, Peter Setlow, Yong-qing Li   +3 more
doaj   +5 more sources

Immunization with Inactivated Bacillus subtilis Spores Expressing TonB-Dependent Receptor (TBDR) Protects Against Multidrug-Resistant Acinetobacter baumannii Infection [PDF]

Vaccines
Background/Objectives: The emergence of multidrug-resistant Acinetobacter baumannii (MDR A. baumannii) as a leading cause of fatal hospital-acquired infections underscores the urgent need for effective vaccines.
Amalia A. Saperi, Atiqah Hazan, Nurfatihah Zulkifli, Hai-Yen Lee, Nor-Aziyah MatRahim, Sazaly AbuBakar   +5 more
doaj   +2 more sources

Probiotic spore-based antigen delivery: a novel oral vaccine strategy against Vibrio infections in aquaculture [PDF]

Microbial Cell Factories
Background Vibriosis is a deadly illness caused by various species of the Vibrio genus. Due to its high incidence in aquaculture plants, vibriosis is responsible for significant economic losses.
Marina De Stefano, Giovanni Di Gregorio Barletta, Simona Morgera, Ylenia De Luca, Chiara Belaeff, Karen Power, Loredana Baccigalupi, Gionata De Vico, Ivan Conte, Ezio Ricca, Anella Saggese   +10 more
doaj   +2 more sources

Progress in Understanding the Molecular Mechanism of Bacterial Spore Germination [PDF]

Shipin Kexue, 2023
In response to nutrient limitation, Bacillus and Clostridium can form metabolically dormant spores, which are extremely resistant to a variety of environmental stresses.
ZHANG Tianyu, LÜ Fengzhi, GUI Meng, WU Xiaomeng, ZHAO Liang, WANG Yongtao, RAO Lei, LIAO Xiaojun
doaj   +1 more source

Oral vaccination of fish against vibriosis using spore-display technology

Frontiers in Immunology, 2022
Oral vaccines are highly demanded by the aquaculture sector, to allow mass delivery of antigens without using the expensive and labor-intensive injectable vaccines. These later require individual handling of fish, provoking stress-related mortalities.One
Gabriela Gonçalves, Gabriela Gonçalves, Rafaela A. Santos, Rafaela A. Santos, Filipe Coutinho, Neide Pedrosa, Maria Curado, Marina Machado, Benjamin Costas, Benjamin Costas, Lourenço Bonneville, Mónica Serrano, António Paulo Carvalho, António Paulo Carvalho, Patricia Díaz-Rosales, Aires Oliva-Teles, Aires Oliva-Teles, Ana Couto, Cláudia R. Serra, Cláudia R. Serra   +19 more
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Phages Bind to Vegetative and Spore Forms of Paenibacillus larvae and to Vegetative Brevibacillus laterosporus

Frontiers in Microbiology, 2021
Paenibacillus larvae is the causative agent of American Foulbrood (AFB), the most destructive bacterial infection in honeybees. Even antibiotic-sensitive strains of P.
T. Scott Brady, Charles R. Roll, Jamison K. Walker, Christopher P. Fajardo, Donald P. Breakwell, Dennis L. Eggett, Sandra Hope   +6 more
doaj   +1 more source

Research Progress on Formation, Germination and Control Methods of Bacterial Spores

Shipin gongye ke-ji, 2023
Bacterial spores are extremely resistant to various processing techniques attributable to its special structure and physiological processes, and often lead to the spoilage of thermally sterilized food. Therefore, it is of great significance to inactivate
Dongchun ZHANG, Yajuan ZHANG, Ying SUN, Haishan SI, Yapeng KANG, Mengge MA, Zhixin WANG, Yawei NING   +7 more
doaj   +1 more source

Comparison of Synergistic Effect of Nisin and Monolaurin on the Inactivation of Three Heat Resistant Spores Studied by Design of Experiments in Milk

Journal of Food Quality, 2021
Spore forming bacteria are special problems for the dairy industry. Heat treatments are insufficient to kill the spores. This is a continuously increasing problem for the industry, but we should be able to control it. In this context, we investigated the
Souhir Kmiha, Chedia Aouadhi, Khouloud Aziza, Awatef Bejaoui, Abderrazak Maaroufi   +4 more
doaj   +1 more source