Results 61 to 70 of about 16,281 (217)
Sporozoite malaria vaccine Where do we stand?
, 2016 A sporozoite malaria vaccine which elicits high levels of antibodies to the circumsporozoite (CS) protein may protect part of the human population in areas of low endemicity.
V. Nussenzweig, S. Nussenzweig
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Following the injection of Plasmodium sporozoites by a female Anopheles mosquito into the dermis, they become engaged on a long journey to hepatic tissue where they must migrate through different types of cell to become established in parasitophorous ...
Gabriela Arévalo-Pinzón +11 more
doaj +1 more source
Malaria parasites differentially sense environmental elasticity during transmission
EMBO Molecular Medicine, 2021 Transmission of malaria‐causing parasites to and by the mosquito relies on active parasite migration and constitutes bottlenecks in the Plasmodium life cycle.
Johanna Ripp +7 more
doaj +1 more source
mBio, 2023 Toxoplasma gondii oocysts, which are shed in large quantities in the feces from infected felines, are very stable in the environment, resistant to most inactivation procedures, and highly infectious. The oocyst wall provides an important physical barrier
David Arranz-Solís +4 more
doaj +1 more source
Trained Immunity in Childhood Vaccination
Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
wiley +1 more source
, 2007 Experimental malaria vaccines based on two sporozoite stage candidate antigens of Plasmodium falciparum, the circumsporozoite protein (CSP) and thrombospondin-related adhesive protein (TRAP), have undergone clinical trials of efficacy.
Sutherland, Colin J +9 more
core +1 more source
Frontiers in Ecology and Evolution, 2019 Although much progress has been made in the fight against malaria, the number of people that contract this disease due to the bite of an Anopheline mosquito remains unacceptably high.
Bianca B. Kojin, Zach N. Adelman
doaj +1 more source
A Genetically Encoded Marker for Imaging of Internal Plasmodium Membranes
Molecular Microbiology, Volume 126, Issue 4, Page 462-472, October 2026.IMMP is a peptide‐based marker that labels internal membranes across multiple stages and species of the malaria‐causing parasite Plasmodium. It works in both live and fixed samples and supports long‐term live‐cell imaging. ABSTRACT Fluorescence microscopy is a powerful tool to analyze the subcellular architecture, and long‐term live‐cell imaging ...
Leah Zink +9 more
wiley +1 more source
Disruption of Plasmodium Sporozoite Transmission by Depletion of Sporozoite Invasion-Associated Protein 1 [PDF]
Eukaryotic Cell, 2009 ABSTRACT Accumulation of infectious Plasmodium sporozoites in Anopheles spp. salivary glands marks the final step of the complex development of the malaria parasite in the insect vector.
Engelmann, S. +2 more
openaire +3 more sources
eLife, 2015 Protection against malaria in humans can be achieved by repeated exposure to infected mosquito bites during prophylactic chloroquine treatment (chemoprophylaxis and sporozoites (CPS)).
Wiebke Nahrendorf +6 more
doaj +1 more source