Results 51 to 60 of about 16,281 (217)
Malaria: A sporozoite runs through it [PDF]
Current Biology, 2001 A recent study reveals new insights into the development of Plasmodium sporozoites, the infectious agents of malaria. These findings may lead to changes in the approach to malaria vaccines and novel interpretations of the mechanisms of immunity to malaria.
Krettli, Antoniana U., Miller, Louis H.
openaire +2 more sources
Medical and Veterinary Entomology, EarlyView.Densities of all Anopheles species were approximately comparable across all IRS regimes. No differences observed between treatment regimes regarding species composition of the Anopheles funestus group or An. gambiae complex. This operational pilot demonstrates the practical feasibility of IRS micro‐mosaics, despite the inherent increase in deployment ...
Dingani Chinula +9 more
wiley +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Distinct Functional Contributions by the Conserved Domains of the Malaria Parasite Alveolin IMC1h
Frontiers in Cellular and Infection Microbiology, 2019 Invasive, motile life cycle stages (zoites) of apicomplexan parasites possess a cortical membrane skeleton composed of intermediate filaments with roles in zoite morphogenesis, tensile strength and motility.
Michael P. Coghlan +5 more
doaj +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Month wise results of sporozoite ELISA test.
, 2015 Month wise results of sporozoite ELISA test.
Venkatachalam Udhyakumar (738524) +8 more
core +1 more source
Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice
Cell Reports, 2017 Malaria sporozoites are deposited into the skin by mosquitoes and infect hepatocytes. The molecular basis of how Plasmodium falciparum sporozoites migrate through host cells is poorly understood, and direct evidence of its importance in vivo is lacking ...
Annie S.P. Yang +14 more
doaj +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.This graphical abstract summarizes a systematic review and meta‐analysis of Toxoplasma gondii in Ethiopia (2012–2025). The study estimated pooled prevalence in ruminants (42.0%) and humans (61.0%) using random‐effects models. Female and adult animals, rural residence, and cat ownership were identified as significant risk factors. The findings emphasize
Ambachew Motbaynor Wubaye +17 more
wiley +1 more source
eLife, 2015 Malaria infection starts with injection of Plasmodium sporozoites by an Anopheles mosquito into the skin of the mammalian host. How sporozoites locate and enter a blood vessel is a critical, but poorly understood process.
Christine S Hopp +6 more
doaj +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.Eimeria tenella is one of the main causes of coccidiosis in poultry, with increasing drug resistance highlighting the need for alternate control strategies. This study identified Eimeria tenella AMA1 (EtAMA1) as a promising vaccine candidate through structural analysis, epitope prediction, immune simulation, and molecular docking, which demonstrated ...
Nooran Mahomed Rafeer +2 more
wiley +1 more source