Results 51 to 60 of about 14,673 (228)
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Killing of Cryptosporidium sporozoites by Lactoferrin [PDF]
The American Journal of Tropical Medicine and Hygiene, 2017 Intestinal infection caused by Cryptosporidium is a major contributor to diarrhea morbidity and mortality in young children around the world. Current treatments for children suffering from cryptosporidiosis are suboptimal. Lactoferrin is a glycoprotein found in breast milk.
Paredes, Jose Luis +5 more
openaire +3 more sources
Month wise results of sporozoite ELISA test. [PDF]
, 2015 Month wise results of sporozoite ELISA test.
Venkatachalam Udhyakumar (738524) +8 more
core +1 more source
Frontiers in Genetics, 2018 Parasite antigen genetic diversity represents a great obstacle when designing a vaccine against malaria caused by Plasmodium vivax. Selecting vaccine candidate antigens has been focused on those fulfilling a role in invasion and which are conserved, thus
Diego Garzón-Ospina +5 more
doaj +1 more source
Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo +8 more
wiley +1 more source
Motility precedes egress of malaria parasites from oocysts
eLife, 2017 Malaria is transmitted when an infected Anopheles mosquito deposits Plasmodium sporozoites in the skin during a bite. Sporozoites are formed within oocysts at the mosquito midgut wall and are released into the hemolymph, from where they invade the ...
Dennis Klug, Friedrich Frischknecht
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Toxoplasmosis is a parasitic disease affecting human, livestock and cat. Prophylactic strategies would be ideal to prevent infection. In a One Health vaccination approach, the objectives would be the prevention of congenital disease in both women and ...
Marie-Noëlle Mévélec +2 more
doaj +1 more source
Integrative Zoology, EarlyView.In an experimental epidemiology setup, groups of pigeons were exposed to different numbers of infective malaria vectors. Vector number explained the speed of transmission, the final prevalence, and changes in host behavior. ABSTRACT Vector density plays a critical role in the transmission dynamics of vector‐borne diseases and thus in their health and ...
Nayden Chakarov +3 more
wiley +1 more source
Malaria: A sporozoite runs through it [PDF]
Current Biology, 2001 A recent study reveals new insights into the development of Plasmodium sporozoites, the infectious agents of malaria. These findings may lead to changes in the approach to malaria vaccines and novel interpretations of the mechanisms of immunity to malaria.
Krettli, Antoniana U., Miller, Louis H.
openaire +2 more sources
Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells [PDF]
, 2002 East Coast fever (ECF) is a fatal disease of cattle caused by the protozoan parasite Theileria parva. The development of a subunit vaccine, based on the sporozoite-specific surface antigen p67, has been hampered by difficulties in achieving high-level ...
Kaba, S.A. +4 more
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