Results 31 to 40 of about 14,673 (228)

Evidence of blood stage efficacy with a virosomal malaria vaccine in a Phase IIa clinical trial [PDF]

, 2008
Background Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine.
Zurbriggen, R, Gerd Pluschke, Sarah C. Gilbert, Hill, Adrian, Hutchings, Claire, Gilbert Sarah C., Sinden, Robert, Gilbert, Sarah, Pluschke, G, Gilbert, Sarah C., Zurbriggen Rinaldo, Vogel, Denise, Jack L. Williams, Correa, S, Andrews Laura, Okitsu, SL, Westerfeld Nicole, Andrews, Laura, Vogel, D, David W. Porter, Thompson, Fiona, Okitsu, Shinji, Ian Poulton, Todryk, S, Shinji L. Okitsu, Denise Vogel, Dunachie Susanna, Thompson Fiona M., Berthoud, Tamara, Andrews, L, Sinden, R, Porter David W., Pluschke, Gerd, Sarah C Gilbert, Sinden Robert, Poulton Ian, Fiona M Thompson, Berthoud, T, Zurbriggen, Rinaldo, Rinaldo Zurbriggen, Susanna Dunachie, Westerfeld, Nicole, Tamara Berthoud, Todryk, Stephen, Okitsu Shinji L., Hill Adrian V. S., Correa Simon, Berthoud Tamara, Dunachie, S, Westerfeld, N, David W Porter, Nicole Westerfeld, Todryk Stephen, Porter, David, Correa, Simon, Thompson, FM, Pluschke Gerd, Hutchings, C, Poulton, Ian, Hutchings Claire, Williams, JL, Vogel Denise, Shinji L Okitsu, Fiona M. Thompson, Poulton, I, Jack L Williams, Simon Correa, Laura Andrews, Dunachie, Susanna, Adrian V S Hill, Robert Sinden, Porter, DW, Stephen Todryk, Williams, Jack, Claire Hutchings, Williams Jack L.   +75 more
core   +2 more sources

Kinetics of Mosquito-Injected Plasmodium Sporozoites in Mice: Fewer Sporozoites Are Injected into Sporozoite-Immunized Mice

PLoS Pathogens, 2009
Malaria is initiated when the mosquito introduces sporozoites into the skin of a mammalian host. To successfully continue the infection, sporozoites must invade blood vessels in the dermis and be transported to the liver. A significant number of sporozoites, however, may enter lymphatic vessels in the skin or remain in the skin long after the mosquito ...
Chahnaz Kebaier, Tatiana Voza, Jerome Vanderberg   +2 more
openaire   +4 more sources

Sporozoite immunization schedule. [PDF]

, 2013
Sporozoite immunization schedule.
Walter R. Weiss (333031), Chengyong George Jiang (333032)   +1 more
core   +1 more source

Preservation of Coccidial Sporozoites by Freezing [PDF]

Nature, 1968
MAINTENANCE of cultures of coccidia for experimental purposes is laborious and expensive. To overcome these difficulties, we attempted to freeze and store sporozoites of Eimeria meleagrimitis Tyzzer, 1929, and E. tenella (Railliet and Lucet, 1891) Fantham, 1909, in liquid nitrogen vapour.
D J, Doran, J M, Vetterling
openaire   +2 more sources

Transition of plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein pumilio [PDF]

, 2011
Many eukaryotic developmental and cell fate decisions that are effected post-transcriptionally involve RNA binding proteins as regulators of translation of key mRNAs.
Gunnar R Mair, Waters, Andrew, Waters, A.P., Prudêncio, M., Joanna Braks, Braks, Joanna, Mair Gunnar R., Braks, J., Theresa Feltwell, Prudêncio, Miguel, Mair, Gunnar R., Gomes-Santos, Carina S. S., Feltwell Theresa, Pain, A., Janse, C., Mota, Maria M., Mota, M.M., Céline Carret, Carret, Céline, Shahid Khan, Gomes, Ana Rita, Khan, S., Miguel Prudêncio, Ana Rita Gomes, Carina S S Gomes-Santos, Mota Maria M., Khan Shahid, Carina S. S. Gomes-Santos, Prudêncio Miguel, Maria M. Mota, Waters Andrew, Gomes-Santos Carina S. S., Gomes-Santos, C.S.S., Gomes, A.R., Mair, G.R., Andrew Waters, Gunnar R. Mair, Gomes Ana Rita, Feltwell, T., Carret Céline, Pain, Arnab, Khan, Shahid, Janse, Chris, Chris Janse, Maria M Mota, Carret, C., Janse Chris, Waters, A., Arnab Pain, Pain Arnab, Feltwell, Theresa, Braks Joanna   +51 more
core   +1 more source

Susceptibility of Anopheles campestris-like and Anopheles barbirostris species complexes to Plasmodium falciparum and Plasmodium vivax in Thailand

Memorias do Instituto Oswaldo Cruz, 2011
Nine colonies of five sibling species members of Anopheles barbirostris complexes were experimentally infected with Plasmodium falciparum and Plasmodium vivax.
Sorawat Thongsahuan, Visut Baimai, Anuluck Junkum, Atiporn Saeung, Gi-Sik Min, Deepak Joshi, Mi-Hyun Park, Pradya Somboon, Wannapa Suwonkerd, Pongsri Tippawangkosol, Narissara Jariyapan, Wej Choochote   +11 more
doaj   +1 more source

Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes [PDF]

, 2012
Malaria is a life-threatening human infectious disease transmitted by mosquitoes. Levels of the salivary gland sporozoites (sgs), the only mosquito stage infectious to a mammalian host, represent an important cumulative index of <i>Plasmodium</i&
Levashina Elena A., Soichot, J., Blandine M Franke-Fayard, Annika Rademacher, Waters Andrew P., Chris J. Janse (12383), Elena A Levashina, Waters, A.P., Jai Ramesar (49002), Chandra Ramakrishnan, Ramakrishnan, C., Andrew P. Waters (15293), Soichot Julien, Costa, G., Costa Giulia, Ramakrishnan Chandra, Levashina, E.A., Giulia Costa (166412), Julien Soichot, Rademacher, A., Janse, C.J., Franke-Fayard Blandine M., Ramesar, J., Annika Rademacher (166404), Elena A. Levashina (160880), Franke-Fayard, B.M., Janse Chris J., Chris J Janse, Jai Ramesar, Rademacher Annika, Ramesar Jai, Blandine M. Franke-Fayard (166421), Giulia Costa, Julien Soichot (166407), Andrew P Waters, Chandra Ramakrishnan (134246)   +35 more
core   +1 more source

Strong concordance between percent inhibition in oocyst and sporozoite intensities in a Plasmodium falciparum standard membrane-feeding assay

Parasites & Vectors, 2019
Background Effective malaria transmission-blocking vaccines (TBVs) can support malaria eradication programmes, and the standard membrane-feeding assay (SMFA) has been used as a “gold standard” assay for TBV development.
Kazutoyo Miura, Bruce J. Swihart, Bingbing Deng, Luwen Zhou, Thao P. Pham, Ababacar Diouf, Michael P. Fay, Carole A. Long   +7 more
doaj   +1 more source

Sporozoite Passage into the Liver Parenchyma [PDF]

, 2013
(A–E) show individual frames extracted from an intravital movie; (F) is a projection visualizing the transmigration path of the GFP P. berghei sporozoite in a Tie2-GFP mouse liver. (G–I) show projections from an intravital movie demonstrating the path of
Herman Yee (120), Ute Frevert (113), Sabine Engelmann (114), Leonard Liebes (119), Kai Matuschewski (118), Jörg Stange (116), Sergine Zougbédé (115), Bruce Ng (117)   +7 more
core   +1 more source

Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

Nature Communications, 2019
Here, the authors report transcriptomes and proteomes of oocyst sporozoite and salivary gland sporozoite stages in rodent-infectious Plasmodium yoelii parasites and human infectious Plasmodium falciparum parasites and define two waves of translational ...
Scott E. Lindner, Kristian E. Swearingen, Melanie J. Shears, Michael P. Walker, Erin N. Vrana, Kevin J. Hart, Allen M. Minns, Photini Sinnis, Robert L. Moritz, Stefan H. I. Kappe   +9 more
doaj   +1 more source