Results 11 to 20 of about 16,281 (217)

Prevalence of anti-p: Falciparum sporozoite antibodies in adults in the amapa region of Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 1987
17 of 20 adult sera from the Amapa region of Brazil were active in the inhibition of P. falciparum sporozoite invasion (ISI) assay which has been correlated with protective antibodies. In contrast 11 sera were positive in IFA tests and 6 were positive in
Virgílio Do Rosario, Michael R. Hollingdale   +1 more
doaj   +3 more sources

Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver.

PLoS ONE, 2017
Whole malaria sporozoite vaccine regimens are promising new strategies, and some candidates have demonstrated high rates of durable clinical protection associated with memory T cell responses. Little is known about the anatomical distribution of memory T
Sathit Pichyangkul, Michele D Spring, Kosol Yongvanitchit, Utaiwan Kum-Arb, Amporn Limsalakpetch, Rawiwan Im-Erbsin, Ratawan Ubalee, Pattaraporn Vanachayangkul, Edmond J Remarque, Evelina Angov, Philip L Smith, David L Saunders   +11 more
doaj   +2 more sources

Susceptibility of two karyotypic forms of Anopheles aconitus (Diptera Culicidae) to Plasmodium falciparum and P. vivax [PDF]

, 2005
Four laboratory-raised colonies of two karyotypic forms of Anopheles aconitus, i.e., Form B (Chiang Mai and Phet Buri strains) and C (Chiang Mai and Mae Hong Son strains), were experimentally infected with Plasmodium falciparum and P.
Komalamisra, Narumon, Choochote, Wej, Suwonkerd, Wannapa, Somboon, Pradya, Saejeng, Aungkana, Jariyapan, Narissara, Bates, Paul A, Junkum, Anuluck, Jitpakdi, Atchariya   +8 more
core   +5 more sources

Plasmodium Actin-Like Proteins 3 and 5a Are Required for Subsequent Steps of Mosquito Infection. [PDF]

Mol Microbiol
Actin‐like proteins (Alps) are highly conserved, apicomplexan‐specific members of the actin superfamily. Using reverse genetics, we have identified that Alp3 and Alp5a are required at separate steps of transmission of the malaria parasite to its mosquito host.
Busse C, Kobayashi Y, Diers A, Binder AM, Frischknecht F, Douglas RG.   +5 more
europepmc   +2 more sources

Cryopreservation of Plasmodium Sporozoites

Pathogens, 2022
Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate development in the liver before infecting erythrocytes and causing clinical malaria.
Carson Bowers, Lisa Hancox, Kristen Peissig, Justine C. Shiau, Amélie Vantaux, Benoit Witkowski, Sivchheng Phal, Steven P. Maher, John T. Harty, Dennis E. Kyle, Samarchith P. Kurup   +10 more
openaire   +3 more sources

Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB₂ in malaria exposed individuals [PDF]

, 2009
Background MB2 protein is a sporozoite surface antigen on the human malaria parasite Plasmodium falciparum. MB2 was identified by screening a P. falciparum sporozoite cDNA expression library using immune sera from a protected donor immunized via the ...
James Anthony A, de la Vega, Patricia, John, Chandy C, Thanh V Nguyen, Nguyen, Thanh V, de la Vega, P, John B Sacci, Patricia de la Vega, James, Anthony A, Kang Angray S, John Chandy C, James, AA, Nguyen, T.V., Sacci, John B, Kang, A.S., Sacci John B, de la Vega, P., Nguyen Thanh V, Anthony A James, de la Vega Patricia, John, C.C., Kang, Angray S, Angray S Kang, Sacci, J.B., Patricia Vega, Chandy C John, John, CC, Nguyen, TV, Kang, AS, Jr, SJB, James, A.A.   +30 more
core   +1 more source

Translational Repression in Malaria Sporozoites [PDF]

Microbial Cell, 2016
Malaria is a mosquito-borne infectious disease of humans and other animals. It is caused by the parasitic protozoan, Plasmodium. Sporozoites, the infectious form of malaria parasites, are quiescent when they remain in the salivary glands of the Anopheles mosquito until transmission into a mammalian host.
Oliver Turque, Tiffany Tsao, Thomas Li, Min Zhang   +3 more
openaire   +3 more sources

Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity [PDF]

, 2008
<i>Plasmodium falciparum</i> sporozoites that develop and mature inside an <i>Anopheles</i> mosquito initiate a malaria infection in humans.
Lasonder Edwin, Edwin Lasonder, Khan, Shahid M., Geert-Jan van Gemert, Gunnar R Mair, Stunnenberg Hendrik G., Waters, A.P., Mann, Matthias, Vermunt Adriaan M. W., Mair Gunnar R., Huynen, Martijn A., Shahid M Khan, Kroeze Hans, Stunnenberg, Hendrik G, Mair, Gunnar R., van Gemert, Geert-Jan, Janse, C., van Gemert Geert-Jan, Sauerwein, R., Janse, C.J., Mann, M., Kroeze, H., Vermunt, Adriaan M. W., Bruno G Douradinha, Luty, A., Vermunt, A.M.W., Khan, S., Vermunt, Adriaan M W, Khan, Shahid M, Chris J Janse, Sauerwein Robert W., van Gemert, G.J., Douradinha, Bruno G., Hans Kroeze, Adriaan M W Vermunt, Robert W Sauerwein, Sauerwein, Robert W., Adrian J F Luty, Andrew P Waters, Kroeze, Hans, Sauerwein, Robert W, Douradinha, B.G., Luty, Adrian J F, Mann Matthias, Waters Andrew P., Lasonder, Edwin, van Noort, V., Luty, A.J.F., Sauerwein, R.W., Huynen Martijn A., Gemert, G.J.A. van, Mair, G.R., Douradinha, B., Khan, S.M., van Noort Vera, Huynen, Martijn A, Noort, V. van, Vera van Noort, Mair, Gunnar R, Janse, Chris J., Khan Shahid M., Stunnenberg, H., van Noort, Vera, Hendrik G Stunnenberg, Douradinha Bruno G., Lasonder, E., Janse, Chris J, Mair, G., Huynen, M., Matthias Mann, Waters, Andrew P, Luty Adrian J. F., van Gemert, G., Waters, A., Waters, Andrew P., Stunnenberg, H.G., Douradinha, Bruno G, Janse Chris J., Stunnenberg, Hendrik G., Luty, Adrian J. F., Huynen, M.A., Martijn A Huynen, Vermunt, A., Janse, CJ, et al,, Mair, GR, Lasonder, E, van Gemert, G-J   +87 more
core   +1 more source

Identification of the Eimeria spp. that infect Linnaeus sheep, 1758, and their morphological characteristics (Ovis aries) in Riyadh City, Saudi Arabia [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
The epidemiology of parasitic infections in sheep is a significant problem in the fields of meat production and human health. Coccidiosis in sheep is one of the major problems caused by protozoan parasites from the genus Eimeria.
A.K.A. Alosaimy, M.S. Alyousif, K.E. Ibrahim, M.M. Mares, H. Alzaylaee, H. Ahmed, M. Murshed   +6 more
doaj   +1 more source

Targetome Analysis of Malaria Sporozoite Transcription Factor AP2-Sp Reveals Its Role as a Master Regulator

mBio, 2023
Malaria transmission to humans begins with sporozoite infection of the liver. The elucidation of gene regulation during the sporozoite stage will promote the investigation of mechanisms of liver infection by this parasite and contribute to the ...
Masao Yuda, Izumi Kaneko, Yuho Murata, Shiroh Iwanaga, Tsubasa Nishi   +4 more
doaj   +1 more source