Results 11 to 20 of about 18,335 (219)
Cryopreservation of Plasmodium Sporozoites
Pathogens, 2022 Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate ...
Carson Bowers +10 more
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Translational repression in malaria sporozoites [PDF]
Microbial Cell, 2016 Malaria is a mosquito-borne infectious disease of humans and other animals. It is caused by the parasitic protozoan, Plasmodium. Sporozoites, the infectious form of malaria parasites, are quiescent when they remain in the salivary glands of the Anopheles
Oliver Turque +3 more
doaj +4 more sources
In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites
International Journal for Parasitology: Drugs and Drug Resistance, 2021 The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3 ...
Ali Daneshmand +9 more
doaj +5 more sources
Vaccination With Sporozoites: Models and Correlates of Protection [PDF]
Frontiers in Immunology, 2019 Despite continuous efforts, the century-old goal of eradicating malaria still remains. Multiple control interventions need to be in place simultaneously to achieve this goal.
Yun Shan Goh +5 more
doaj +5 more sources
Dynamics of Toxoplasma gondii Oocyst Phagocytosis by Macrophages
Frontiers in Cellular and Infection Microbiology, 2020 Oocysts are the environmentally resistant stage of the protozoan parasite Toxoplasma gondii. They are responsible for foodborne infections in humans and animals worldwide.
Omar Ndao +16 more
doaj +1 more source
Specific EtMIC3-binding peptides inhibit Eimeria tenella sporozoites entry into host cells
Veterinary Research, 2021 Avian coccidiosis caused by Eimeria leads to huge economic losses on the global poultry industry. In this study, microneme adhesive repeat regions (MARR) bc1 of E.
Wenjing Chen +6 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Hepatocyte invasion by Plasmodium sporozoites represents a promising target for innovative antimalarial therapy, but the molecular events mediating this process are still largely uncharacterized. We previously showed that Plasmodium falciparum sporozoite
Nadia Amanzougaghene +23 more
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Plasmodium Actin-Like Proteins 3 and 5a Are Required for Subsequent Steps of Mosquito Infection. [PDF]
Mol MicrobiolActin‐like proteins (Alps) are highly conserved, apicomplexan‐specific members of the actin superfamily. Using reverse genetics, we have identified that Alp3 and Alp5a are required at separate steps of transmission of the malaria parasite to its mosquito host.
Busse C +5 more
europepmc +2 more sources
The Plasmodium eukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands [PDF]
, 2010 Sporozoites, the invasive form of malaria parasites transmitted by mosquitoes, are quiescent while in the insect salivary glands. Sporozoites only differentiate inside of the hepatocytes of the mammalian host. We show that sporozoite latency is an active
Sullivan, W. J. +49 more
core +1 more source
Frontiers in Chemistry, 2020 We have demonstrated previously that amino-artemisinins including artemiside and artemisone in which an amino group replaces the oxygen-bearing substituents attached to C-10 of the current clinical artemisinin derivatives dihydroartemisinin (DHA ...
Ho Ning Wong +12 more
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