Results 11 to 20 of about 12,830 (178)

Cryopreservation of Plasmodium Sporozoites

open access: yesPathogens, 2022
Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate ...
Carson Bowers   +10 more
doaj   +3 more sources

Translational repression in malaria sporozoites [PDF]

open access: yesMicrobial Cell, 2016
Malaria is a mosquito-borne infectious disease of humans and other animals. It is caused by the parasitic protozoan, Plasmodium. Sporozoites, the infectious form of malaria parasites, are quiescent when they remain in the salivary glands of the Anopheles
Oliver Turque   +3 more
doaj   +3 more sources

Vaccination With Sporozoites: Models and Correlates of Protection [PDF]

open access: yesFrontiers in Immunology, 2019
Despite continuous efforts, the century-old goal of eradicating malaria still remains. Multiple control interventions need to be in place simultaneously to achieve this goal.
Yun Shan Goh   +5 more
doaj   +5 more sources

Natural Vector of Avian Haemoproteus asymmetricus Parasite and Factors Altering the Spread of Infection

open access: yesInsects, 2023
Avian haemosporidians (Apicomplexa, Haemosporida) are widespread blood protists, often causing severe haemosporidiosis, pathology, or even mortality in their hosts.
Rita Žiegytė   +2 more
doaj   +1 more source

In Vitro Antiparasitic Activity of Propyl-Propane-Thiosulfinate (PTS) and Propyl-Propane-Thiosulfonate (PTSO) from Allium cepa against Eimeria acervulina Sporozoites

open access: yesMicroorganisms, 2022
Among the alternatives to control avian coccidiosis, alliaceous extracts stand out due to their functional properties. Despite this, most of the references are focused just on garlic.
María Arántzazu Aguinaga-Casañas   +5 more
doaj   +1 more source

Sporozoite immunization: Innovative Translational Science to Support the Fight against malaria

open access: yesExpert Review of Vaccines, 2023
Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especially
Thomas L. Richie   +45 more
doaj   +1 more source

Dynamics of Toxoplasma gondii Oocyst Phagocytosis by Macrophages

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Oocysts are the environmentally resistant stage of the protozoan parasite Toxoplasma gondii. They are responsible for foodborne infections in humans and animals worldwide.
Omar Ndao   +16 more
doaj   +1 more source

Specific EtMIC3-binding peptides inhibit Eimeria tenella sporozoites entry into host cells

open access: yesVeterinary Research, 2021
Avian coccidiosis caused by Eimeria leads to huge economic losses on the global poultry industry. In this study, microneme adhesive repeat regions (MARR) bc1 of E.
Wenjing Chen   +6 more
doaj   +1 more source

The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Hepatocyte invasion by Plasmodium sporozoites represents a promising target for innovative antimalarial therapy, but the molecular events mediating this process are still largely uncharacterized. We previously showed that Plasmodium falciparum sporozoite
Nadia Amanzougaghene   +23 more
doaj   +1 more source

Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies–Activities Against Blood Stage P. falciparum Including PfKI3 C580Y Mutants and Liver Stage P. berghei Parasites

open access: yesFrontiers in Chemistry, 2020
We have demonstrated previously that amino-artemisinins including artemiside and artemisone in which an amino group replaces the oxygen-bearing substituents attached to C-10 of the current clinical artemisinin derivatives dihydroartemisinin (DHA ...
Ho Ning Wong   +12 more
doaj   +1 more source

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