Results 31 to 40 of about 18,335 (219)

Identification of the glycan binding profile of human and rodent Plasmodium sporozoites

, 2021
The transmission of Plasmodium spp. sporozoites to the mammalian host is the first step in the initiation of the mosquito-borne disease known as malaria.
Doolan, Denise L., Groves, Penny L, Day, Christopher J., Stanisic, Danielle, Jennings, Michael P, Tiralongo, Joe, Doolan, Denise L, Hartley-Tassell, Lauren E., Hoffman, Stephen L., Sim, B Kim Lee, Stanisic, Danielle I., Groves, Penny L., Bovin, Nicolai, Chakravarty, Sumana, Lee Sim, B. Kim, Hartley-Tassell, Lauren E, Poole, Jessica, Jennings, Michael P., Day, Christopher J, Hoffman, Stephen L, Lauren E. Hartley-Tassell, Danielle I. Stanisic, Stephen L. Hoffman, Christopher J. Day, Michael P. Jennings, Penny L. Groves, B. Kim Lee Sim, Nicolai Bovin, Denise L. Doolan, Jessica Poole, Sumana Chakravarty, Joe Tiralongo   +31 more
core   +1 more source

Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite-immobilizing antibodies [PDF]

Infection and Immunity, 1986
A monoclonal antibody directed against the circumsporozoite protein on the surface of Plasmodium berghei sporozoites inhibited sporozoite motility in vitro. These immobilized sporozoites could adhere to but not invade target cultured cells. Other sporozoite-immobilizing agents also inhibited sporozoite invasion into cultured cells and did not prevent ...
M J, Stewart, R J, Nawrot, S, Schulman, J P, Vanderberg   +3 more
openaire   +2 more sources

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes [PDF]

, 2008
Difficulties with inducing sterile and long lasting protective immunity against malaria with subunit vaccines has renewed interest in vaccinations with attenuated <i>Plasmodium</i> parasites.
Melissa R van Dijk, Ben C L van Schaijk, Geert-Jan van Gemert, Yalaoui Samir, Schaijk, B.C.L. van, Waters, A.P., van Gemert, G. J., Franetich Jean-Francois, Samir Yalaoui, Shahid M Khan, van de Vegte-Bolmera, M., Silvie, O., Hoffman, S. L., Franetich, J.F., van Gemert Geert-Jan, Janse, C.J., Vegte-Bolmer, M.G. van de, Yalaouic, S., Khan, S. M., Chris J Janse, Stephen L Hoffman, Sauerwein Robert W., Silvie Olivier, Sauerwein, R. W., Robert W Sauerwein, Andrew P Waters, Hoffman, S.L., van Dijk, M. R., Waters Andrew P., Sauerwein, R.W., Jean-Francois Franetich, Gemert, G.J.A. van, van de Vegte-Bolmer Marga, Khan, S.M., Olivier Silvie, Mazier, D., Gegoc, A., Gego, A., Khan Shahid M., Franetich, J. F., Dijk, M.R. van, Dominique Mazier, Audrey Gego, Yalaoui, S., Waters, A. P., Janse, C. J., van Schaijk Ben C. L., van Dijk Melissa R., van Schaijk, B. C. L., Janse Chris J., Gego Audrey, Mazier Dominique, Marga van de Vegte-Bolmer, Hoffman Stephen L.   +53 more
core   +2 more sources

Conoid fibre number variation in sporozoites from pre-excystation sporocysts, freshly excysted and intracellular.

, 2022
A: Segmentation of sporozoite conoids from pre-excystation sporozoites within sporocysts, freshly excysted and intracellular sporozoites. The numbers next to sporocysts indicates matching sporozoites within a sporocyst;. (TIF)
Alana Burrell (6314069), Virginia Marugan-Hernandez (3445442), Flavia Moreira-Leite (5924531), Sue Vaughan (20216), Richard Wheeler (4449133), Fiona M. Tomley (7381571), David J. P. Ferguson (7484639)   +6 more
core   +1 more source

Preservation of Coccidial Sporozoites by Freezing [PDF]

Nature, 1968
MAINTENANCE of cultures of coccidia for experimental purposes is laborious and expensive. To overcome these difficulties, we attempted to freeze and store sporozoites of Eimeria meleagrimitis Tyzzer, 1929, and E. tenella (Railliet and Lucet, 1891) Fantham, 1909, in liquid nitrogen vapour.
D J, Doran, J M, Vetterling
openaire   +2 more sources

Sporozoites display active motility inside the mosquito.

, 2022
Movie showing three sporozoites imaged in close proximity to the salivary gland. Sporozoites appear to be attached to a larger vessel and observed movements might be a combination of active motility and passive hemolymph flow.
Katharina Arnold (2502364), Eric Marois (245559), Dennis Klug (2878652), Raquel Mela-Lopez (13948986), Stéphanie A. Blandin (3661318)   +4 more
core   +1 more source

Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development

Memorias do Instituto Oswaldo Cruz, 2011
CD8+ T cells against malaria liver stages represent a major protective immune mechanism against infection. Following induction in the peripheral lymph nodes by dendritic cells (DCs), these CD8+ T cells migrate to the liver and eliminate parasite infected
Sze-Wah Tse, Andrea J Radtke, Fidel Zavala   +2 more
doaj   +1 more source

In vitro: Anti-coccidia activity of Calotropis procera leaf extract on Eimeria papillata oocysts sporulation and sporozoite

Open Chemistry, 2022
Natural products play an important role as environmentally friendly agents that can be used against parasitic diseases. Many Eimeria species cause eimeriosis in poultry. The negative effects of synthetic anti-coccidiosis medications necessitate the quest
Murshed Mutee, Al-Quraishy Saleh, Qasem Mahmood A.   +2 more
doaj   +1 more source

Infectivity of Symptomatic Patients and Their Contribution for Infectiousness of Mosquitoes following a Membrane Feeding Assay in Ethiopia

Microbiology Spectrum, 2022
The membrane feeding assay is widely used to evaluate the efficacy of transmission-blocking interventions (TBIs) and identify the reservoir of malaria.
Andargie Abate, Soriya Kedir, Mitiku Bose, Jifar Hassen, Laurent Dembele, Lemu Golassa   +5 more
doaj   +1 more source

Malaria: A sporozoite runs through it [PDF]

Current Biology, 2001
A recent study reveals new insights into the development of Plasmodium sporozoites, the infectious agents of malaria. These findings may lead to changes in the approach to malaria vaccines and novel interpretations of the mechanisms of immunity to malaria.
Krettli, Antoniana U., Miller, Louis H.
openaire   +2 more sources