Results 21 to 30 of about 12,830 (178)

Culicoides segnis and Culicoides pictipennis Biting Midges (Diptera, Ceratopogonidae), New Reported Vectors of Haemoproteus Parasites

Microorganisms, 2022
As bloodsuckers of birds, Culicoides biting midges (Diptera, Ceratopogonidae) play an important role in the transmission of avian haemosporidian (Haemoproteus) parasites, which are prevalent in many bird populations and cause disease, pathology, or even ...
Rita Žiegytė, Rasa Bernotienė, Vaidas Palinauskas   +2 more
doaj   +1 more source

Effect of the Aedes fluviatilis saliva on the development of Plasmodium gallinaceum infection in Gallus (gallus) domesticus

Memorias do Instituto Oswaldo Cruz, 2004
Effect of Aedes fluviatilis saliva on the development of Plasmodium gallinaceum experimental infection in Gallus (gallus) domesticus was studied in distinct aspects.
Ana CVM da Rocha, Érika M Braga, Márcio SS Araújo, Bernardo S Franklin, Paulo FP Pimenta   +4 more
doaj   +1 more source

The mucin-like, secretory type-I transmembrane glycoprotein GP900 in the apicomplexan Cryptosporidium parvum is cleaved in the secretory pathway and likely plays a lubrication role

Parasites & Vectors, 2022
Background Cryptosporidium parvum is a zoonotic parasite and member of the phylum Apicomplexa with unique secretory organelles, including a rhoptry, micronemes and dense granules that discharge their contents during parasite invasion.
Xiaohui Li, Jigang Yin, Dongqiang Wang, Xin Gao, Ying Zhang, Mingbo Wu, Guan Zhu   +6 more
doaj   +1 more source

Immunization with CSP and a RIG-I Agonist is Effective in Inducing a Functional and Protective Humoral Response Against Plasmodium

Frontiers in Immunology, 2022
Malaria is a major public health concern, as a highly effective human vaccine remains elusive. The efficacy of a subunit vaccine targeting the most abundant protein of the sporozoite surface, the circumsporozoite protein (CSP) has been hindered by ...
Ana Rafaela Teixeira, Ana Rafaela Teixeira, Ana Rafaela Teixeira, Begoña Pérez-Cabezas, Begoña Pérez-Cabezas, David M. Costa, David M. Costa, Mónica Sá, Mónica Sá, Mónica Sá, Sylvain Golba, Hélèna Sefiane-Djemaoune, Joana Ribeiro, Joana Ribeiro, Izumi Kaneko, Shiroh Iwanaga, Masao Yuda, Moriya Tsuji, Silvia Beatriz Boscardin, Silvia Beatriz Boscardin, Rogerio Amino, Anabela Cordeiro-da-Silva, Anabela Cordeiro-da-Silva, Anabela Cordeiro-da-Silva, Joana Tavares, Joana Tavares, Joana Tavares   +26 more
doaj   +1 more source

ATG Ubiquitination Is Required for Circumsporozoite Protein to Subvert Host Innate Immunity Against Rodent Malaria Liver Stage

Frontiers in Immunology, 2022
Although exo-erythrocytic forms (EEFs) of liver stage malaria parasite in the parasitophorous vacuole (PV) are encountered with robust host innate immunity, EEFs can still survive and successfully complete the infection of hepatocytes, and the underlying
Hong Zheng, Hong Zheng, Hong Zheng, Xiao Lu, Xiao Lu, Kai Li, Feng Zhu, Chenhao Zhao, Taiping Liu, Yan Ding, Yong Fu, Kun Zhang, Taoli Zhou, Jigang Dai, Yuzhang Wu, Wenyue Xu, Wenyue Xu   +16 more
doaj   +1 more source

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.

PLoS ONE, 2013
BackgroundControlled human malaria infection (CHMI) studies have become a routine tool to evaluate efficacy of candidate anti-malarial drugs and vaccines.
Susanne H Sheehy, Alexandra J Spencer, Alexander D Douglas, B Kim Lee Sim, Rhea J Longley, Nick J Edwards, Ian D Poulton, Domtila Kimani, Andrew R Williams, Nicholas A Anagnostou, Rachel Roberts, Simon Kerridge, Merryn Voysey, Eric R James, Peter F Billingsley, Anusha Gunasekera, Alison M Lawrie, Stephen L Hoffman, Adrian V S Hill   +18 more
doaj   +1 more source

Studies on malarial sporozoites. II. Effect of age and dosage of sporozoites on their infectiousness [PDF]

Experimental Parasitology, 1954
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/32533/1/0000635 ...
Porter, Richard J., Laird, Raymond L., Dusseau, Elizabeth M.   +2 more
openaire   +3 more sources

Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite-immobilizing antibodies [PDF]

Infection and Immunity, 1986
A monoclonal antibody directed against the circumsporozoite protein on the surface of Plasmodium berghei sporozoites inhibited sporozoite motility in vitro. These immobilized sporozoites could adhere to but not invade target cultured cells. Other sporozoite-immobilizing agents also inhibited sporozoite invasion into cultured cells and did not prevent ...
M J, Stewart, R J, Nawrot, S, Schulman, J P, Vanderberg   +3 more
openaire   +2 more sources

Preservation of Coccidial Sporozoites by Freezing [PDF]

Nature, 1968
MAINTENANCE of cultures of coccidia for experimental purposes is laborious and expensive. To overcome these difficulties, we attempted to freeze and store sporozoites of Eimeria meleagrimitis Tyzzer, 1929, and E. tenella (Railliet and Lucet, 1891) Fantham, 1909, in liquid nitrogen vapour.
D J, Doran, J M, Vetterling
openaire   +2 more sources

Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development

Memorias do Instituto Oswaldo Cruz, 2011
CD8+ T cells against malaria liver stages represent a major protective immune mechanism against infection. Following induction in the peripheral lymph nodes by dendritic cells (DCs), these CD8+ T cells migrate to the liver and eliminate parasite infected
Sze-Wah Tse, Andrea J Radtke, Fidel Zavala   +2 more
doaj   +1 more source