Results 41 to 50 of about 14,501 (156)

Avian malaria co-infections confound infectivity and vector competence assays of Plasmodium homopolare. [PDF]

open access: yes, 2018
Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly. In the current study, we experimentally measured the vector competence of several Culex mosquitoes for a newly ...
Barker, Christopher M   +5 more
core   +1 more source

ELISPOT assay to measure antigen-specific murine CD8(+) T cell responses.

open access: yes, 2001
The enzyme-linked immunospot technique (ELISPOT) relies on the visualization of cytokine secretion by individual T cells following in vitro stimulation with antigen. This assay has been developed and standardized for the quantitative detection of antigen-
Carvalho, LH, Hafalla, JC, Zavala, F
core   +1 more source

Killing of Plasmodium Sporozoites by Basic Amphipathic α-Helical Fusion Peptides

open access: yesMicroorganisms
Membranolytic molecules constitute the first line of innate immune defense against pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these cytotoxic molecules in the hemolymph and salivary glands of mosquitoes, as well as in ...
Manuela C. Aguirre-Botero   +6 more
doaj   +1 more source

Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells [PDF]

open access: yes, 2002
East Coast fever (ECF) is a fatal disease of cattle caused by the protozoan parasite Theileria parva. The development of a subunit vaccine, based on the sporozoite-specific surface antigen p67, has been hampered by difficulties in achieving high-level ...
Kaba, S.A.   +4 more
core   +2 more sources

A potent adjuvant effect of a CD1d-binding NKT cell ligand in human immune system mice

open access: yesExpert Review of Vaccines, 2017
Objectives: A CD1d-binding invariant natural killer T (iNKT)-cell stimulatory glycolipid, namely 7DW8-5, is shown to enhance the efficacy of radiation-attenuated sporozoites (RAS)-based malaria vaccine in mice.
Xiangming Li   +6 more
doaj   +1 more source

Dendritic cells in plasmodium infection [PDF]

open access: yes, 2008
Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso   +15 more
core   +2 more sources

Neospora caninum and Bovine Neosporosis: Current Vaccine Research [PDF]

open access: yes, 2017
Neospora caninum, a tissue cyst-forming parasite, is the causative agent of bovine neosporosis. It is considered to be one of the most important transmissible causes of reproductive failure in cattle; abortion and neonatal mortality result in significant
Marugan-Hernandez, V
core   +2 more sources

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

open access: yesSmall, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran   +10 more
wiley   +1 more source

Morphological and Molecular Characterization of Eimeria saudiensis From Arabian Oryx (Oryx leucoryx) Held in Captivity in the Sultanate of Oman 阿曼苏丹国圈养阿拉伯羚羊 (Oryx leucoryx) 体内沙特艾美球虫 (Eimeria saudiensis) 的形态学与分子特征

open access: yesWildlife Letters, EarlyView.
Eimeria saudiensis represents a genus of apicomplexan parasites capable of inducing coccidiosis in Arabian oryx. Our research concentrated on the morphological and molecular investigation of Eimeria spp. in the captive oryx herd in Oman. The therapeutic and management practices employed at the Mammals Breeding Center were reassessed to diminish ...
Khalid Al‐Habsi   +7 more
wiley   +1 more source

Effects of Vector Density on Blood Parasite Spread and Health Consequences for Avian Hosts: An Experimental Epidemiology Blueprint

open access: yesIntegrative Zoology, EarlyView.
In an experimental epidemiology setup, groups of pigeons were exposed to different numbers of infective malaria vectors. Vector number explained the speed of transmission, the final prevalence, and changes in host behavior. ABSTRACT Vector density plays a critical role in the transmission dynamics of vector‐borne diseases and thus in their health and ...
Nayden Chakarov   +3 more
wiley   +1 more source

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