Results 171 to 180 of about 28,326 (246)

Adding Tat‐Beclin1 to an endurance training program promotes additive improvements in physical function in aged male mice

Physiological Reports, Volume 14, Issue 19, October 2026.
Abstract Autophagy is a hallmark of aging, but it has not been exclusively targeted to attenuate aging‐related physical dysfunction. Here, we combined Tat‐Beclin1 and endurance training to determine its effect on physical function domains in aged male mice.
Thuan Thien Tchen, Shakibur Rahman, Thaysa Ghiarone, Lynn A. Spruce, Hossein Fazelinia, Elizabeth M. Brown, Charalampos Papachristou, Sue C. Bodine, Vitor A. Lira, Kleiton A. S. Silva   +9 more
wiley   +1 more source

Clinical significance of SQSTM1 variants in ALS: report of p.Arg119Cys and literature review. [PDF]

Neurogenetics
Su B, Li L, Zheng X, Ma H, Li X, Feng X.
europepmc   +1 more source

A <i>de novo VPS16</i> missense variant blocks autophagic flux and extends DYT-<i>VPS16</i> into infancy. [PDF]

Autophagy Rep
Gonzalez Saez-Diez E, Xue X, Ebrahimi-Fakhari D.   +2 more
europepmc   +1 more source

The SQSTM1 L341V Variant Associated With Sporadic ALS Promotes the Accumulation of Enlarged Ubiquitin-Positive SQSTM1 Bodies. [PDF]

Genes Cells
Shimakura K, Oka A, Yudahira H, Hama Y, Otomo A, Hadano S.   +5 more
europepmc   +1 more source

Integrative analysis of drug-gene signatures in human pluripotent stem cells reveals prazosin as a novel SQSTM1 regulator for ALS therapeutics. [PDF]

Stem Cell Reports
Roussange F, Gide J, Tournois J, Cailleret M, Boland A, Battail C, Deleuze JF, Polvèche H, Auboeuf D, Brockmann K, Kabashi E, Marian A, El Kassar L, Blondel S, Salachas F, Bruneteau G, Peschanski M, Martinat C, Baghdoyan S.   +18 more
europepmc   +1 more source

SPOP-mediated nuclear ubiquitination degradation of p62/SQSTM1 contributes to HR repair. [PDF]

Oncogene
Yang X, Zhou Y, Huang Q, Wang L, Zhang S, Yang X, Qiu L, Meng Y, Wu H, Zhang B, Xie K, Han J, Zhu Q.   +12 more
europepmc   +1 more source

Autophagy-Ferroptosis Crosstalk in Dry Eye Disease: Context-Dependent Regulation of Ocular Surface Homeostasis. [PDF]

Cells
Zhong Y, Peng J, Peng Q.
europepmc   +1 more source

Rewiring ALS by modulating the autophagy receptor SQSTM1. [PDF]

Stem Cell Reports
Aubry L, Korolchuk VI, Sarkar S.
europepmc   +1 more source

Functionalized Fluorescent Nanodiamonds Reveal Therapeutic Protein Clearance Through ENDOTAC Linked to AUTOTAC. [PDF]

Adv Healthc Mater
Lin YW, Lai YH, Pang JY, Lin YC, Chang TT, Fang IH, Wang RH, Chang CJ, Chiang IH, Wu SY, Lin HH, Chen LY, Su LJ, Chao JI.   +13 more
europepmc   +1 more source

Myoclonus and Gaze Palsy in Childhood-Onset SQSTM1-Related Neurodegeneration. [PDF]

J Mov Disord
Ganguly J, Roychowdhury S, Keshav R, Dutta D, Mukherjee S, Basu P, Kumar H.   +6 more
europepmc   +1 more source