Results 141 to 150 of about 111,466 (171)

Emerging role for SRC family kinases in junction dynamics during spermatogenesis. [PDF]

Reproduction, 2019
Xiao X, Yang Y, Mao B, Cheng CY, Ni Y.
europepmc   +1 more source

Src family kinases (SFKs) and cell polarity in the testis. [PDF]

Semin Cell Dev Biol, 2018
Xiao X, Ni Y, Yu C, Li L, Mao B, Yang Y, Zheng D, Silvestrini B, Cheng CY.   +8 more
europepmc   +1 more source

Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans. [PDF]

Proc Natl Acad Sci U S A, 2019
Abe K, Cox A, Takamatsu N, Velez G, Laxer RM, Tse SML, Mahajan VB, Bassuk AG, Fuchs H, Ferguson PJ, Hrabe de Angelis M.   +10 more
europepmc   +1 more source

Src family kinases in lung cancer

, 2010
Rupniewska, E, Watling, D, Mauri, FA, Pardo, OE, Seckl, MJ   +4 more
openaire   +1 more source

Src Family Kinases in Intracerebral Hemorrhage

, 2014
openaire   +3 more sources

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Encodable Activators of Src Family Kinases

Journal of the American Chemical Society, 2006
There is considerable current interest in the design of encodable molecules that regulate intracellular protein circuitry and/or activity, ideally with a high level of specificity. Src homology 3 (SH3) domains are ubiquitous components of multidomain signaling proteins, including many kinases, and are attractive drug targets because of the important ...
Crystal D, Zellefrow, Jennifer S, Griffiths, Sarmistha, Saha, Abby M, Hodges, Jessica L, Goodman, Joshiawa, Paulk, Joshua A, Kritzer, Alanna, Schepartz   +7 more
openaire   +2 more sources

Structures of Src-family tyrosine kinases

Current Opinion in Structural Biology, 1997
The crystal structures of three Src-family tyrosine kinases have been determined recently. The structure of the catalytic domain of Lck has been determined in the active autophosphorylated state. The structures of larger constructs of c-Src and Hck, containing the SH3, SH2 and catalytic domains, as well as a C-terminal regulatory tail, have been ...
F, Sicheri, J, Kuriyan
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CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

Annual Review of Cell and Developmental Biology, 1997
▪ Abstract  Src family protein tyrosine kinases are activated following engagement of many different classes of cellular receptors and participate in signaling pathways that control a diverse spectrum of receptor-induced biological activities. While several of these kinases have evolved to play distinct roles in specific receptor pathways, there is ...
S M, Thomas, J S, Brugge
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GPCRs Signaling Directly Through Src-Family Kinases

Science's STKE, 2007
A wide range of extracellular signals are transduced by G protein–coupled receptors (GPCRs). When activated by ligands, GPCRs can activate associated heterotrimeric guanine nucleotide–binding proteins (G proteins), which in turn act on various effectors.
Deirdre, McGarrigle, Xin-Yun, Huang
openaire   +2 more sources

New Src-Family Kinase Activator

Science's STKE, 2003
Members of the Src familiy of protein kinases contribute to signals emanating from various receptors on the cell membrane, but the mechanisms by which the receptors modulate kinase activity is unclear. Members of the Src family show interactions between protein domains that are thought to control kinase activity.
openaire   +2 more sources