Results 101 to 110 of about 512,141 (378)
Phosphorylation of a Src Kinase at the Autophosphorylation Site in the Absence of Src Kinase Activity [PDF]
Journal of Biological Chemistry, 2000 Exposure of cells to oxidants increases the phosphorylation of the Src family tyrosine protein kinase Lck at Tyr-394, a conserved residue in the activation loop of the catalytic domain. Kinase-deficient Lck expressed in fibroblasts that do not express any endogenous Lck has been shown to be phosphorylated at Tyr-394 following H(2)O(2) treatment to an ...
Gary G. Chiang +2 more
openaire +3 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Australian and New Zealand Journal of Public Health, 2015 Objective: Obesity is the single biggest public health threat to developed and developing economies. In concert with healthy public policy, multi‐strategy, multi‐level community‐based initiatives appear promising in preventing obesity, with several ...
Jillian Whelan +9 more
doaj +1 more source
Frontiers in Psychology, 2016 According to theories of addictive behaviors, approach and attentional biases towards smoking-related cues play a crucial role in tobacco dependence.
Marcella Lydia Woud +5 more
doaj +1 more source
Collaborative Representation based Classification for Face Recognition [PDF]
, 2014 By coding a query sample as a sparse linear combination of all training samples and then classifying it by evaluating which class leads to the minimal coding residual, sparse representation based classification (SRC) leads to interesting results for ...
Feng, Xiangchu +4 more
core
Confident Kernel Sparse Coding and Dictionary Learning
, 2019 In recent years, kernel-based sparse coding (K-SRC) has received particular attention due to its efficient representation of nonlinear data structures in the feature space.
Hammer, Barbara, Hosseini, Babak
core +1 more source
Characterization of anti-leukemia components from Indigo naturalis using comprehensive two-dimensional K562/cell membrane chromatography and in silico target identification. [PDF]
, 2016 Traditional Chinese Medicine (TCM) has been developed for thousands of years and has formed an integrated theoretical system based on a large amount of clinical practice.
Cao, Yan +9 more
core +1 more source
Nature Communications, 2014 Duchenne muscular dystrophy (DMD) is a fatal degenerative muscle disease resulting from mutations in the dystrophin gene. Increased oxidative stress and altered Ca2+ homeostasis are hallmarks of dystrophic muscle.
Rituraj Pal +8 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz +2 more
wiley +1 more source
4 open, 2019 The attempt to restore homeostasis, once disrupted, such that complex signaling, crosstalk between ubiquitous proteins, and a diverse range of pathways gone awry is near impossible, especially in the presence of an ongoing pathogenic stimuli with ...
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source