Results 181 to 190 of about 168,331 (269)

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Reviewer #2 (Public Review): Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

open access: gold
Ling Zhou   +16 more
openalex   +1 more source

A Novel Approach to Regionalize Country‐Level GDP Projections

open access: yesJournal of Forecasting, EarlyView.
ABSTRACT Socioeconomic projections are policy support tools that are often limited to country‐level data, making them insufficient for policy areas that require a more nuanced, sub‐national perspective. For granular geographical analyses in a multicountry setting, international organizations often rely on straightforward regionalization techniques ...
Riccardo Curtale   +2 more
wiley   +1 more source

Efzimfotase Alfa Improves Respiratory Capacity in Muscle Tissue From a Mouse Model of HPP. [PDF]

open access: yesJIMD Rep
Devore D   +10 more
europepmc   +1 more source

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