Results 211 to 220 of about 512,141 (378)

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

ChemBioChem, EarlyView.
SLIPT‐PM enables the translocation of tag‐fused proteins from the cytoplasm to the plasma membrane using a synthetic self‐localizing ligand. This user‐friendly system permits reversible control of diverse signaling pathways. This concept article highlights the key features and current applications of SLIPT‐PM as a powerful tool in chemical and ...
Shuya Ohira, Akinobu Nakamura, Kenta Terai, Shinya Tsukiji   +3 more
wiley   +1 more source

Exploring the potential value of SRC in pan cancer based on bioinformatics methods. [PDF]

Discov Oncol
Huang L, Lu Y, Yi L, Zhao Y, Si T, Zhang M.   +5 more
europepmc   +1 more source

Solvent refined coal (SRC) process: Operation of solvent refined coal pilot plant. Quarterly technical progress report, January--March 1978

, 1978
H. Lewis, W. Weber, G. Usnick, W. Hollenack, H. Hooks, R. Boykin   +5 more
openalex   +2 more sources

Activity Analysis of the P2X Receptor Antagonist PPADS against Signal Transducer and Activator of Transcription Proteins

ChemBioChem, EarlyView.
The P2X receptor antagonist PPADS possesses activity against members of the signal transducer and activator of transcription (STAT) family of transcription factors, in particular STAT4, STAT5a, and STAT5b. PPADS protects STAT4 and STAT5a/STAT5b from thermal degradation in cell lysates to a higher extent than STAT3.
Angela Berg, Martin Gräber, Thorsten Berg   +2 more
wiley   +1 more source

Integrin β5 interacts with G3BP1 through activating FAK/Src signaling pathway to promote gastric carcinogenesis. [PDF]

Sci Rep
Liu D, Cao J, Hu K, Peng Z.
europepmc   +1 more source

Solvent refined coal (SRC) process operation of solvent refined coal pilot plant. Annual report, January-December 1978

, 1979
H. Lewis, W. Weber, G. Usnick, W. Hollenack, H. S. Blair, R. Boykin   +5 more
openalex   +2 more sources

Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma

ChemMedChem, EarlyView.
Pyrazolo[1,5‐α]pyrimidinone derivatives exhibit selective cytotoxicity towards glioblastoma (GBM) cells over noncancerous cells. Structure–activity relationship studies identifies a lead compound with significant cytotoxicity activity, inducing apoptosis and necrosis in GBM cells, without affecting noncancerous cells. This demonstrates the potential of
Kate Byrne, Natalia Bednarz, Ciara McEvoy, John C. Stephens, James F. Curtin, Gemma K. Kinsella   +5 more
wiley   +1 more source

Mechanistic insights into the effects of Tris-2-butoxyethyl phosphate on multiple cancers using network toxicology and molecular docking. [PDF]

Sci Rep
Lu H, Huang P, Huang B, He D, Ou X, Xu Z, Li S.   +6 more
europepmc   +1 more source

Studies in coal liquefaction with application to the SRC and related processes. Final summary report, July 1976-July 1878

, 1979
J.A. Guin, A. Tarrer
openalex   +2 more sources

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source