Results 31 to 40 of about 12,750 (218)
International Journal of Cardiology: Heart & Vasculature, 2021 Objectives: Soluble suppression of tumorigenicity 2 (sST2) is a member of the interleukin-1 receptor family. It is raised in various cardiovascular diseases, but its value in predicting disease severity or mortality outcomes has been controversial ...
Christina Ip +14 more
doaj +1 more source
Association of IL1R1 Coding Variant With Plasma-Level Soluble ST2 and Risk of Aortic Dissection
Frontiers in Cardiovascular Medicine, 2021 Objective: Aortic dissection (AD) is characterized by an acute onset, rapid progress, and high mortality. Levels of soluble ST2 (sST2) on presentation are elevated in patients with acute AD, which can be used to discriminate AD patients from patients ...
Wenxi Jiang +23 more
doaj +1 more source
Effects of canagliflozin on cardiovascular biomarkers in older adults with type 2 diabetes [PDF]
, 2017 Background: Sodium glucose co-transporter 2 (SGLT2) inhibitors may reduce cardiovascular and heart failure risk in patients with type 2 diabetes mellitus (T2DM).
Butler, Javed +6 more
core +1 more source
EJNMMI Research, 2020 Purpose Although somatostatin receptor (SST) is a promising theranostic target and is widely expressed in tumors of various organs, the indication for therapies targeting SST is limited to typical gastroenteropancreatic neuroendocrine tumors (NETs). Thus,
Hyunjong Lee +7 more
doaj +1 more source
ST2 in Stable and Unstable Ischemic Heart Diseases [PDF]
, 2015 Circulating suppression of tumorigenicity 2 (ST2) predicts cardiovascular outcomes and mortality in ischemic heart disease (IHD). ST2 does not correlate with traditional risk indicators as closely as N-terminal pro–brain natriuretic peptide (NT-proBNP ...
DI SOMMA, Salvatore +2 more
core +1 more source
PLoS ONE, 2020 BackgroundProinflammatory interleukin-33 (IL-33) binds to its receptor ST2L and is involved in inflammation and the malignant behavior of cancer cells.
Keizo Takenaga +3 more
doaj +1 more source
Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy
Medicina, 2022 Background and Objectives: A prognosis for kids with pediatric dilated cardiomyopathy (PDCM) is urgently needed to identify high-risk patients. This study aimed to determine the association of levels and soluble suppression of tumorigenicity 2 (sST2) and
Meng Jiao +7 more
doaj +1 more source
Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1
Cells, 2020 Circulating levels of soluble interleukin 1 receptor-like 1 (sST2) are increased in heart failure and associated with poor outcome, likely because of the activation of inflammation and fibrosis.
Lara Matilla +14 more
doaj +1 more source
Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window [PDF]
, 2020 During the implantation window, the endometrium becomes poised to transition to a pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC).
Brighton, Paul (Paul J.) +12 more
core +1 more source
The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling [PDF]
Journal of Biological Chemistry, 1997 Activation of the somatostatin receptor sst2, a member of the Gi protein-coupled receptor family, results in the stimulation of a protein-tyrosine phosphatase activity involved in the sst2-mediated growth inhibitory signal. Here, we report that SHP-1, a cytoplasmic protein-tyrosine phosphatase containing two Src homology 2 domains constitutively ...
F, Lopez +8 more
openaire +2 more sources