Results 11 to 20 of about 5,477 (176)

WAT-to-BAT communication facilitates the sustained activation of BAT thermogenesis during cold exposure [PDF]

Cell Discovery
The activation of brown adipose tissue (BAT) for thermogenesis represents a crucial physiological mechanism that helps maintain body temperature during cold exposure.
Jieyuan Xue, Ding Chen, Chenfeng Wang, Jue Wang, Jiayu Zhou, Wenyan Li, Junxi Qian, Yuanji Huang, Liang Fang, Hongyong Song, Ben He, Xu-Yun Zhao   +11 more
doaj   +2 more sources

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21 [PDF]

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +2 more sources

Elevated sST2 associates with cardiac involvement and declines after treatment in newly diagnosed patients with idiopathic inflammatory myopathies [PDF]

Arthritis Research & Therapy
Objective Cardiac involvement (CI) is a major determinant of poor prognosis in idiopathic inflammatory myopathies (IIM). Soluble suppression of tumorigenicity 2 (sST2) is a biomarker linked to cardiac inflammation and remodelling, but its role has ...
Balsam Hanna, Ingrid E. Lundberg, Anna-Karin H. Ekwall, Daniel Glinatsi, Egidija Sakiniene, Zhicheng Hu, Rille Pullerits, Tao Jin   +7 more
doaj   +2 more sources

Soluble ST2 levels for predicting the presence and severity of metabolic syndrome

Endocrine Connections, 2021
To explore the relationship between soluble ST2 (sST2) and metabolic syndrome (MetS) and determine whether sST2 levels can predict the presence and severity of MetS.
Xiao Zong, Qin Fan, Hang Zhang, Qian Yang, Hongyang Xie, Qiujing Chen, Ruiyan Zhang, Rong Tao   +7 more
doaj   +1 more source

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? [PDF]

PLoS ONE, 2012
Preliminary data mostly from animal models suggest the sST2/IL-33 pathway may have causal relevance for vascular disease and diabetes and thus point to a potential novel inflammatory link to cardiometabolic disease.
Ashley M Miller, David Purves, Alex McConnachie, Darren L Asquith, G David Batty, Harry Burns, Jonathan Cavanagh, Ian Ford, Jennifer S McLean, Chris J Packard, Paul G Shiels, Helen Turner, Yoga N Velupillai, Kevin A Deans, Paul Welsh, Iain B McInnes, Naveed Sattar   +16 more
doaj   +1 more source

Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation

Frontiers in Cardiovascular Medicine, 2021
Objective: A more extensively fibrotic left atrium contributes to atrial fibrillation (AF) occurrence, persistence, and recurrence. The soluble suppression of tumorigenicity 2 (sST2) has emerged as a ventricular fibrotic biomarker for patients with heart
Ruopeng Tan, Ruopeng Tan, Haixu Yu, Xu Han, Yang Liu, Xiaolei Yang, Yun-Long Xia, Yun-Long Xia, Xiaomeng Yin   +8 more
doaj   +1 more source

Role of soluble ST2 in short-term prediction of acute heart failure in acute ST-elevation myocardial infarction

Российский кардиологический журнал, 2021
Aim. To investigate the relationship of soluble ST2 (sST2) to acute heart failure (AHF) and compare the predictive value of sST2 and brain natriuretic peptide in patients with ST-elevation myocardial infarction (STEMI).Material and methods.
O. S. Donirova, K. V. Protasov, B. A. Donirov, E. V. Batunova   +3 more
doaj   +1 more source

The pro-inflammatory marker soluble suppression of tumorigenicity-2 (ST2) is reduced especially in diabetic morbidly obese patients undergoing bariatric surgery

Cardiovascular Diabetology, 2020
Background High soluble suppression of tumorigenicity-2 (sST2) is a marker of poor prognosis in chronic inflammatory conditions. ST2 and its ligand interleukin (IL)-33 are elevated in adipose tissue of obese individuals.
Svitlana Demyanets, Christoph Kaun, Alexandra Kaider, Walter Speidl, Manfred Prager, Stanislav Oravec, Philipp Hohensinner, Johann Wojta, Gersina Rega-Kaun   +8 more
doaj   +1 more source

The serum levels and clinical significance of interleukin-33 and soluble ST2 in patients with vitiligo

Pifu-xingbing zhenliaoxue zazhi, 2020
Objective: To investigate the clinical significance of interleukin-33(IL-33) and soluble ST2 (sST2) in patients with vitiligo. Methods: The serum concentrations of IL-33 and sST2 were determined by enzyme linked immunosorbent assay (ELISA) respectively ...
Li YANG, Dong-qing LU, Han MA
doaj   +1 more source

Analytical performances of a new rapid assay of soluble ST2 for cardiac and inflammatory diseases and establishment of the reference intervals for children and adolescence in China

Practical Laboratory Medicine, 2023
Background: sST2 has emerged as a potential disease biomarker of cardiac and inflammatory diseases in pediatrics. This study aimed to evaluate the performance of the new Pylon sST2 assay and establish the reference intervals of sST2 in children and ...
Zhicheng Ye, Chuanshu Chen, Shiwei Chen, Menghua Xu, Jin Xu   +4 more
doaj   +1 more source