Results 11 to 20 of about 5,690 (176)

Sex and age differences in sST2 in cardiovascular disease

open access: yesFrontiers in Cardiovascular Medicine, 2023
AimsThe goal of this study was to determine whether sex and age differences exist for soluble ST2 (sST2) for several cardiovascular diseases (CVDs).MethodsWe examined sST2 levels using an ELISA kit for myocarditis (n = 303), cardiomyopathy (n = 293 ...
Danielle J. Beetler   +30 more
doaj   +3 more sources

Prognostic Value of sST2 in Heart Failure

open access: yesJournal of Clinical Medicine, 2023
In recent years, there has been growing interest in the risk stratification for heart failure, and the use of multiple biomarkers to identify different pathophysiological processes associated with this condition. One such biomarker is soluble suppression of tumorigenicity-2 (sST2), which has shown some potential for integration into clinical practice ...
Sciatti E.   +9 more
openaire   +3 more sources

Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation

open access: yesFrontiers in Cardiovascular Medicine, 2021
Objective: A more extensively fibrotic left atrium contributes to atrial fibrillation (AF) occurrence, persistence, and recurrence. The soluble suppression of tumorigenicity 2 (sST2) has emerged as a ventricular fibrotic biomarker for patients with heart
Ruopeng Tan   +8 more
doaj   +1 more source

Role of soluble ST2 in short-term prediction of acute heart failure in acute ST-elevation myocardial infarction

open access: yesРоссийский кардиологический журнал, 2021
Aim. To investigate the relationship of soluble ST2 (sST2) to acute heart failure (AHF) and compare the predictive value of sST2 and brain natriuretic peptide in patients with ST-elevation myocardial infarction (STEMI).Material and methods.
O. S. Donirova   +3 more
doaj   +1 more source

The pro-inflammatory marker soluble suppression of tumorigenicity-2 (ST2) is reduced especially in diabetic morbidly obese patients undergoing bariatric surgery

open access: yesCardiovascular Diabetology, 2020
Background High soluble suppression of tumorigenicity-2 (sST2) is a marker of poor prognosis in chronic inflammatory conditions. ST2 and its ligand interleukin (IL)-33 are elevated in adipose tissue of obese individuals.
Svitlana Demyanets   +8 more
doaj   +1 more source

The serum levels and clinical significance of interleukin-33 and soluble ST2 in patients with vitiligo

open access: yesPifu-xingbing zhenliaoxue zazhi, 2020
Objective: To investigate the clinical significance of interleukin-33(IL-33) and soluble ST2 (sST2) in patients with vitiligo. Methods: The serum concentrations of IL-33 and sST2 were determined by enzyme linked immunosorbent assay (ELISA) respectively ...
Li YANG, Dong-qing LU, Han MA
doaj   +1 more source

Analytical performances of a new rapid assay of soluble ST2 for cardiac and inflammatory diseases and establishment of the reference intervals for children and adolescence in China

open access: yesPractical Laboratory Medicine, 2023
Background: sST2 has emerged as a potential disease biomarker of cardiac and inflammatory diseases in pediatrics. This study aimed to evaluate the performance of the new Pylon sST2 assay and establish the reference intervals of sST2 in children and ...
Zhicheng Ye   +4 more
doaj   +1 more source

The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling [PDF]

open access: yesJournal of Biological Chemistry, 1997
Activation of the somatostatin receptor sst2, a member of the Gi protein-coupled receptor family, results in the stimulation of a protein-tyrosine phosphatase activity involved in the sst2-mediated growth inhibitory signal. Here, we report that SHP-1, a cytoplasmic protein-tyrosine phosphatase containing two Src homology 2 domains constitutively ...
F, Lopez   +8 more
openaire   +2 more sources

The IL-33/sST2 Axis in Thromboangiitis Obliterans.

open access: yesJournal of inflammation research, 2020
Until recently, it remains unknown whether thromboangiitis obliterans (TAO) is a type of systemic vasculitis. A high level of IL-33 and its soluble decoy receptor sST2 in the acute phase of systemic vasculitis has been demonstrated.The serum level of IL-33 and sST2 in 50 TAO patients, 20 age- and smoking habit-matched controls and 19 age-matched non ...
Sharebiani,Hiva   +3 more
openaire   +4 more sources

A pan-cancer analysis of the clinical and genetic portraits of somatostatin receptor expressing tumor as a potential target of peptide receptor imaging and therapy

open access: yesEJNMMI Research, 2020
Purpose Although somatostatin receptor (SST) is a promising theranostic target and is widely expressed in tumors of various organs, the indication for therapies targeting SST is limited to typical gastroenteropancreatic neuroendocrine tumors (NETs). Thus,
Hyunjong Lee   +7 more
doaj   +1 more source

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