Results 31 to 40 of about 5,477 (176)
The Association of Serum IL-33 and sST2 with Breast Cancer [PDF]
Disease Markers, 2015 Breast cancer is one of the most common malignant diseases in women. The main cause of death from breast cancer is its metastases at distant sites in the body. Interleukin-33 (IL-33) is a cytokine of the IL-1 family and found overexpressed in various cancers.
Yang, Zhi-Ping +8 more
openaire +2 more sources
Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1
Cells, 2020 Circulating levels of soluble interleukin 1 receptor-like 1 (sST2) are increased in heart failure and associated with poor outcome, likely because of the activation of inflammation and fibrosis.
Lara Matilla +14 more
doaj +1 more source
PLoS ONE, 2020 BackgroundProinflammatory interleukin-33 (IL-33) binds to its receptor ST2L and is involved in inflammation and the malignant behavior of cancer cells.
Keizo Takenaga +3 more
doaj +1 more source
Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy
Medicina, 2022 Background and Objectives: A prognosis for kids with pediatric dilated cardiomyopathy (PDCM) is urgently needed to identify high-risk patients. This study aimed to determine the association of levels and soluble suppression of tumorigenicity 2 (sST2) and
Meng Jiao +7 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundBoth β1 adrenergic receptor autoantibody (β1-AA) and soluble suppression of tumorigenicity-2 (sST2) take a role in the pathological remodeling of heart failure.
Yanxiang Sun +6 more
doaj +1 more source
Filamin-A is required to mediate SST2 effects in pancreatic neuroendocrine tumours [PDF]
Endocrine-Related Cancer, 2016 Somatostatin receptor type 2 (SST2) is the main pharmacological target of somatostatin (SS) analogues widely used in patients with pancreatic neuroendocrine tumours (P-NETs), this treatment being ineffective in a subset of patients. Since it has been demonstrated that Filamin A (FLNA) is involved in mediating GPCR expression, membrane anchoring and ...
E. Vitali +8 more
openaire +3 more sources
Conflicting vascular and metabolic impact of the IL-33/sST2 axis [PDF]
Cardiovascular Research, 2018 Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra- and extracellularly to either enhance or resolve the inflammatory response. Intracellular IL-33 acts in the nucleus as a regulator of transcription.
Altara, Raffaele +5 more
openaire +3 more sources
Mediators of Inflammation, 2022 Background. Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disease with high heterogeneity and postoperative recidivation. The IL-33/ST2 axis is known to be involved in Th2 immune responses.
Yanni Zhang +8 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Background: Recent studies have suggested that soluble suppression of tumorigenicity-2 (sST2), an inflammation-related protein receptor, is associated with atherosclerotic diseases.
Guqing Luo +9 more
doaj +1 more source
Reply: Interleukin-1β and sST2.
Journal of the American College of Cardiology, 2020 ©2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Accepted version of a Published Work that appeared in final form inJACC: Cardiovascular Imaging.
Pascual Figal, Domingo A. +2 more
openaire +2 more sources