Results 31 to 40 of about 5,690 (176)

Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1

Cells, 2020
Circulating levels of soluble interleukin 1 receptor-like 1 (sST2) are increased in heart failure and associated with poor outcome, likely because of the activation of inflammation and fibrosis.
Lara Matilla, Vanessa Arrieta, Eva Jover, Amaia Garcia-Peña, Ernesto Martinez-Martinez, Rafael Sadaba, Virginia Alvarez, Adela Navarro, Amaya Fernandez-Celis, Alicia Gainza, Enrique Santamaria, Joaquín Fernandez-Irigoyen, Patrick Rossignol, Faiez Zannad, Natalia Lopez-Andres   +14 more
doaj   +1 more source

Filamin-A is required to mediate SST2 effects in pancreatic neuroendocrine tumours [PDF]

Endocrine-Related Cancer, 2016
Somatostatin receptor type 2 (SST2) is the main pharmacological target of somatostatin (SS) analogues widely used in patients with pancreatic neuroendocrine tumours (P-NETs), this treatment being ineffective in a subset of patients.
E. Vitali, V. Cambiaghi, A. Zerbi, C. Carnaghi, P. Colombo, E. Peverelli, A. Spada, G. Mantovani, A. G. Lania   +8 more
openaire   +3 more sources

Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model.

PLoS ONE, 2020
BackgroundProinflammatory interleukin-33 (IL-33) binds to its receptor ST2L and is involved in inflammation and the malignant behavior of cancer cells.
Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Hiroki Nagase   +3 more
doaj   +1 more source

Prognostic Value of β1 Adrenergic Receptor Autoantibody and Soluble Suppression of Tumorigenicity-2 in Patients With Acutely Decompensated Heart Failure

Frontiers in Cardiovascular Medicine, 2022
BackgroundBoth β1 adrenergic receptor autoantibody (β1-AA) and soluble suppression of tumorigenicity-2 (sST2) take a role in the pathological remodeling of heart failure.
Yanxiang Sun, Li Feng, Bing Hu, Jianting Dong, Liting Zhang, Xuansheng Huang, Yong Yuan   +6 more
doaj   +1 more source

Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy

Medicina, 2022
Background and Objectives: A prognosis for kids with pediatric dilated cardiomyopathy (PDCM) is urgently needed to identify high-risk patients. This study aimed to determine the association of levels and soluble suppression of tumorigenicity 2 (sST2) and
Meng Jiao, Xiaofang Wang, Yongmei Liang, Yifei Yang, Yan Gu, Zhiyuan Wang, Zhenyu Lv, Mei Jin   +7 more
doaj   +1 more source

Predictive Values of Serum IL-33 and sST2 in Endotypes and Postoperative Recurrence of Chronic Rhinosinusitis with Nasal Polyps

Mediators of Inflammation, 2022
Background. Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disease with high heterogeneity and postoperative recidivation. The IL-33/ST2 axis is known to be involved in Th2 immune responses.
Yanni Zhang, Kang Zhu, Jingguo Chen, Cui Xia, Chao Yu, Tianxi Gao, Jing Yan, Bingjie Zhao, Xiaoyong Ren   +8 more
doaj   +1 more source

Reply: Interleukin-1β and sST2.

Journal of the American College of Cardiology, 2020
©2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Accepted version of a Published Work that appeared in final form inJACC: Cardiovascular Imaging.
Pascual Figal, Domingo A., Lax Pérez, Antonio Manuel, Bayes Genis, Antoni   +2 more
openaire   +2 more sources

Conflicting vascular and metabolic impact of the IL-33/sST2 axis [PDF]

Cardiovascular Research, 2018
Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra- and extracellularly to either enhance or resolve the inflammatory response. Intracellular IL-33 acts in the nucleus as a regulator of transcription.
Altara, Raffaele, Ghali, Rana, Mallat, Ziad, Cataliotti, Alessandro, Booz, George W, Zouein, Fouad A   +5 more
openaire   +3 more sources

Soluble Suppression of Tumorigenicity‐2 Predicts Mortality and Right Heart Failure in Patients With a Left Ventricular Assist Device

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Soluble suppression of tumorigenicity‐2 (sST2) predicts mortality in patients with heart failure. The predictive value of sST2 in patients with a left ventricular assist device remains unknown.
Lieke Numan, Emmeke Aarts, Faiz Ramjankhan, Marish I. F. Oerlemans, Manon G. van der Meer, Nicolaas de Jonge, Anne‐Marie Oppelaar, Hans Kemperman, Folkert W. Asselbergs, Linda W. Van Laake   +9 more
doaj   +1 more source

Elevated Serum Levels of Soluble ST2 Are Associated With Plaque Vulnerability in Patients With Non-ST-Elevation Acute Coronary Syndrome

Frontiers in Cardiovascular Medicine, 2021
Background: Recent studies have suggested that soluble suppression of tumorigenicity-2 (sST2), an inflammation-related protein receptor, is associated with atherosclerotic diseases.
Guqing Luo, Yuxuan Qian, Xincheng Sheng, Jiateng Sun, Zhinan Wu, Fei Liao, Qi Feng, Yan Yin, Song Ding, Jun Pu   +9 more
doaj   +1 more source